Daniel Lin, MD @DanielLinMD
GI Medical Oncologist 🐈 🐱 Dad @KimmelCancerCtr @TJUHospital 🏳️🌈 Philadelphia, PA Joined November 2019-
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🔥off the press🔥 Expanding the path to cure - a narrative review on optimizing multimodality sequencing in HCC 👉HCC management is shifting toward a personalized, multimodal continuum, a 🇨🇦 perspective 👇my author link authors.elsevier.com/c/1nURW15X3~m1… @myESMO @ASCO
It's out in print! The COMPETE phase III trial of patients with GEPNETs. Mostly (83-86%) pre-treated patients with GEPNETs (pancreas 57-58%, small bowel (24-26%). 2:1 randomization to 177Lu-DOTATOC vs. everolimus. The primary endpoint, PFS, strongly favors Lu-177 DOTATOC, 23.9 vs. 14.1 months. No difference in OS but data not mature and as always, it is difficult to evaluate OS as many patients will ultimately get PRRT outside of a trial. Therefore, OS is not a suitable endpoint for NET trials. This is very important new data on sequencing of systemic therapy beyond first line. No new safety signals. Bravo to the COMPETE team including @Ja_Capdevila @GCarboneroLab @JHernando3 @drdelolmo_mbel sciencedirect.com/science/articl…
Great overview of the latest updates on #NETs at @myESMO #ESMOGI26 🆕Belzutifan in VHL ☢️Advances in #PRRT 💊Summary of approved drugs #ESMOAmbassadors @GCarboneroLab @GrupoGetne @ENETS_ORG
Selecting appropriate strategy #HCC @ma5RN giving fabulous BCLC overview- navigating early/intermediate ➡️combos no OS benefit to date ➡️Using CUSE & available evidence to help select tools at MDT ➡️noting the ‘real world’ patient & the patient preference #ESMOGI26 @OncoAlert
🔥RAS inhibition in #PDAC #ESMOGI26 ➡️Daraxonrasib as new 2nd line std 1st-line data as mono or in combo GnP ➡️G12Di in combo with chemo ➡️multiple new drugs & some falling off further dvpt ➡️optimal sequences/combos to come ⭐️all patients need access asap! @myESMO @OncoAlert
🗞️Here it is, our latest paper on #adjuvant treatment in #BiliaryMalignancies 😬Improvement is much needed 🧐Will #IO be the answer? 🧐Shall we move to #neoadjuvant? tandfonline.com/doi/figure/10.… @Alex_MedOnc @Hospital_FJD
Day 5 #ASCO26 highlights: 1. #HER2CLIMB05: Tucatinib maintenance in HER2 metastatic breast cancer 2. ADC in 1L mTNBC 3. #SERENA6: Camizestrant in HR+ Breast Ca 4. #VIKTORIA1: Gedatolisib in HR+ Breast Ca 5. #REDUSE: DeEscalation BMA #OncTwitter @ASCO @OncoAlert 1/6🙏🏽
🔥 More is not always the best REDUCE trial demonstrated that every 12 weeks denosumab is not inferior to standard every 4 weeks ✅ Non inferior efficacy ✅ Improved safety profile ✅ Reduce cost I love this type of trials! Congratulations to all investigators
Day 3 & 4 #ASCO26 highlights: 1. #evERA: Giredestrant in mHR+ BC 2. #ASCENT03/04: Saci 1L mTNBC 3. #CIRCULATE: ctDNA in CRC 4. #EPISODE3: Adj Aspirin in CRC 5. #EMERALD3: STRIDE + TACE + Len in HCC 6. #DeLLphi304: Tarla in SCLC @ASCO #OncTwitter @OncoAlert 1/7
#ASCO2026 - Advanced Gastric cancer Abstract 4007 - Adding oral EP4 antagonist ONO-4578 to chemo + IO in Stage IV gastric cancer. - Median PFS was significantly longer with ONO-4578 vs placebo 9.0 vs 6.9 months; HR 0.67; 90% CI 0.48–0.92; P=0.040. - Median OS favored ONO-4578 (not reached vs 12.7 months; HR 0.60; 95% CI 0.37–0.96). - ORR was higher in the ONO-4578 group (62.0% vs 48.7%). Serious TEAEs occurred in 53.7% vs 42.7%. IMPORTANT: Results were better for PD-L1 positive tumors. This Phase II RCT shows that adding the EP4 antagonist ONO-4578 to standard nivo + chemo improves PFS and trends toward OS benefit in 1L HER2-negative gastric/GEJ cancer. Although OS data are immature and this is a Phase II trial, this is a first demonstration that PGE2-EP4 pathway inhibition can enhance immunotherapy efficacy in this setting - warranting Phase III confirmation. #GIonc #StomachCancer @MoffittNews
EMERALD-1, EMERALD-3, CARES-005, LEAP-012, (and maybe Imbrave 050, although for post-resection or ablation; and EMERALD-Y90 for post-Y90) all test a similar idea: will adjuvant systemic therapy improve outcomes after local regional therapy? PFS benefits are seen across all studies (except 050). But OS are all immature. Are we just giving systemic therapy earlier for these patients who would eventually have more advanced disease? Without final OS, post-TACE systemic therapy is probably not given universally as of today. Hopefully we will have the data soon. But for some high risk patients, there might be benefits. We need to investigate who in the control arm “have no chance” to receive systemic therapy upon progression. Those are the patients we want to consider treating earlier. And the debates continue…
@GABOUALFA PhIII EMERALD-3 trial of TACE + durva/treme + len (Arm A) vs TACE + STRIDE (B) vs TACE (C) in #HCC not amenable to #LRT ➡️ median PFS 13.0 vs 9.8 mos & OS 39.5 vs 34.7 mos (HR 0.84, 40% mature) (Arm A vs C), equivalency for Arm A vs B outcomes no #ASCO26 @OncoAlert
Dr. Marlana Orloff presented results from the OptimUM-02 trial of darovasertib + crizotinib in metastatic uveal melanoma at #ASCO26 ➡️ asco.org/abstracts-pres…
Important study re: ctDNA for non-op surveillance in rectal ca. Pos ctDNA associated w regrowth (60%) & distant mets (60%), but neg ctDNA doesn't exclude local regrowth (sensitivity only 41%) ctDNA good for risk stratification but not surveillance replacement #ASCO26 @OncoAlert
Day 3 #ASCO26 5 plenary highlights: 1. #PROTEUS: PeriOp/PostOp Apa in Prostate Ca 2. #SARC041: Adj Abema in dediff liposarcoma 3. #LIBRETTO432 : Adj Selpercatinib in NSCLC 4. #HARMONi6: 1L Ivonescimab in Sq mNSCLC 5. #RASolute302: 2L Daraxonrasib in Panc Ca @ASCO 1/6
Nilvanstomig, an anti- PD-1/TIGIT bispecific, plus beva vs. sintilimab plus beva biosimilar as 1L for advanced HCC: A randomized, multi-center, phase II trial #ASCO26ORR 👉ORR 54 vs 50 vs 34% 👉mPFS NR vs NR vs 5.8 🧐Interesting data, supports targeting TIGIT in HCC @myesmo @ASCOPost
“X % of patients found the side effects acceptable” strikes me as far more authentic than “manageable toxicity”, and acknowledges who’s actually experiencing the AEs! When the patient & oncologist meet, there are 2 experts in the room: one embodied & one necessarily removed
The most important paper of #ASCO26 just dropped in Nature Med! Or any other @ASCO or @myESMO meetings to be honest. When you hear someone present “the toxicities were acceptable”, please respond “downplaying toxicities is not acceptable”. Thank you @NatureMedicine for publishing
#ASCO26 @ASCO FIGHT-302 @GIcancerDoc 1L Pemigatinib vs gem/cis in FGFR2-rearranged advanced cholangiocarcinoma Closed early d/t change in 1L SOC, n=167 (4563 screened, <4% positivity rate) - ORR 47% vs 15% - PFS 8.3m vs 6.8m - no diff in OS with 50% crossover (mOS 24.4m vs 25m) Kudos for this effort 👏 Simultaneous @JCO_ASCO publication @OncoAlert #BTCsm
Mark Lewis, MD, FASCO @marklewismd
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ASCO @ASCO
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Blood Research @Blood_Res
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academic_young_oncolo... @Agoder_academia
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Galip Can Uyar @uyargalip
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Roupen Odabashian @RoupenMD
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Nancy Q @ersinkaygusuz11
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Grace @Grace455940
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1104Health @1104_Health
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Annals of Laboratory ... @AnnLabMed
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OncoNexus @Onco_Nexus
162 Followers 541 Following Oncology Nexus is a real-world oncology insights platform led by multidisciplinary physicians delivering multimedia to an audience of oncology specialists.
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CancerNetwork® @CancerNetwrk
30K Followers 762 Following Home of the journal ONCOLOGY®, CancerNetwork® offers different perspectives on oncology/hematology through review articles, news, podcasts, blogs, and more.
Juan OConnor @Juanmaoconnor
958 Followers 555 Following Buenos Aires, Argentina, Head of GI oncology, @IAF. papa y futbol fan ⚽️
✝️Pope Saint John... @pp2chome
2K Followers 7K Following ✝️🙏PAX VOBISCUM |Pray the Rosary|Bible|Orphans|Widows|Special needs|Refugees|We are a 400+ PROLIFE,TLM,100%Roman Catholic Church founded Orphanage and Sch.🙏✝️
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96K Followers 35K Following Director, GI Oncology, @Intermountain. Interests: neuroendocrine tumors, cancer syndromes, empathy (even had a Whipple myself). Tweets my own.
Pashtoon Kasi MD, MS @pashtoonkasi
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Anwaar Saeed @AnwaarSaeed3
3K Followers 1K Following Associate Professor & Chief of Gastrointestinal Oncology @PittTweet @UPMCnews @UPMCHillmanCC
Vivek Subbiah, MD @VivekSubbiah
41K Followers 2K Following Drug Development| Precision Oncology| Tissue-Agnostic Precision Medicine #Oncologist, #Phase1trials, #PrecisionMedicine. Tweets=My own.
Sam Klempner @KlempnerSam
5K Followers 681 Following GI medical oncologist focusing on stomach and esophageal cancer research at Massachusetts General Hospital, Harvard Medical School
Anirban Maitra @Aiims1742
34K Followers 3K Following Pancreatic cancer researcher, GI pathologist, husband, dad. Striving to improve the lives of patients with cancer. 🇺🇸 🇮🇳
Thor Halfdanarson @OncoThor
6K Followers 2K Following 🇮🇸Medical Oncologist/Educator, NET/GI/CUP enthusiast. Husband/dadx4 (bad dad jokes). Cyclist. Avant gardener. Professor of Oncology, Mayo Clinic. Tweets mine.
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6K Followers 3K Following @mayoclinic AZ #Pancreaticcancer #Colorectalcancer #cholangiocarcinoma #Livercancer #Lebanon #Freedom Retweets/Follows not endorsements. Views my own.
Paolo Tarantino @PTarantinoMD
32K Followers 800 Following MD, PhD, Medical Oncologist | Clinical Fellow @DanaFarber | @Harvard. Associate Editor @ESMO_Open. Interested in breast oncology, HER2, ADCs and good music.
Shaalan Beg MD MBA FA... @ShaalanBeg
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12K Followers 5K Following VICC Assoc Director, Strategic Relations and Research Partnerships, Exec Director, Young Adult Cancers Program; Co-Chair, NCI GI Steering Committee
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Ibrahim Halil SAHIN, ... @IbrahimSahinMD1
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ASCO @ASCO
152K Followers 2K Following Account of the American Society of Clinical Oncology & its affiliate the Association for Clinical Oncology. Assoc tweets labeled #ASCOAdvocacy. RTs ≠ endorse.
Stephen V Liu, MD @StephenVLiu
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Binaytara @binaytara
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Nicholas Hornstein @GIMedOnc
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457 Followers 1K Following GU Onc RF @DanaFarber | Applicant IM MATCH 2027 🇺🇸 | M.D. ’24 @LebaneseUni | Prev RA @aubmc Oncology, germline genetics, immunotherapy
COLONTOWN @colontown
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Dr. Thomas Ichim @exosome
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Richard Zheng @RZheng8
475 Followers 453 Following HPB surgical oncologist at @JeffersonSurgery by way of @HopkinsSurgery, @StonyBrookMed. Proud Chinese-American, dog dad, Knicks fan, in no particular order.
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744 Followers 1K Following Director of the Cancer Center - Prof. of Medical Oncology at CHA Bundang Medical Center; specializing in #HPB #LiverCancer #Cholangiocarcinoma #Immunotherapy
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Jefferson @WeAreJefferson
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OLN Great Debates in ... @OLNGreatDebates
652 Followers 252 Following The Meeting Where Oncology Professionals Don’t Just Learn... They Debate
Nicole Baranda Balmac... @NBalmacedaMD
180 Followers 320 Following GI Oncologist at UT MD Anderson | Conquering Cancer with novel therapies and ctDNA 🧪 in pancreatic cancer | PDAC and CRC research | Millennial dog mom to Nivo
Genes & Diseases Jour... @GenesNDiseases
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Margaret Wheless, MD @MargaretWheless
105 Followers 152 Following PGY6 heme onc fellow with a GI onc interest 🩺 and outdoor enthusiast 🏔️ @UTHSCMedicine @VUMCMedicineRes @lipscomb tweets are my own
Dr. Hamamoto Laborato... @HamamotoLab
616 Followers 585 Following NCC Japan Official Account approved in Dec. 2025. Dr. Hamamoto: Division Chief (NCC)/Team Director (RIKEN)/Professor of NCC Medical Science (Science Tokyo).
OncoDaily @oncodaily
10K Followers 9K Following Where the global cancer community meets - daily news, trial breakdowns. KOL interviews, live from major cancer congresses OncoDaily - The Voice of Oncology
Wagner Eduardo Cruz D... @educruzdiaz12
43 Followers 206 Following Médico Oncólogo Instituto Nacional de enfermedades Neoplásicas
OncUpdates @OncUpdates
912 Followers 736 Following Latest oncology insights for medical professionals and patients| Curating the latest in research, trials & treatment advances| Own Views| Not medical advice
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342 Followers 274 Following Chief GI Onc ; Director of clinical trials and clinical research solid tumors @Christianacare. Working to improve research in EOCRC. founding member @gutonclab
Mary Feng @MaryFengMD
874 Followers 284 Following Radiation doctor, oncologist, liver cancer specialist
Sukeshi Arora MD @DrSukeshiArora
1K Followers 631 Following Yogi, medical oncologist caring for patients with GI cancers, she/her. Views are my own. insta: @yogaoncology
Enrique Grande @drenriquegrande
13K Followers 9K Following Medical Oncology Department Director at Quironsalud Madrid. Opinions are my own. https://t.co/DrJu4J331O
Renata D'Alpino @RenataDAlpino
391 Followers 308 Following Oncologist - Gastrointestinal and Neuroendocrine Tumors Centro Paulista de Oncologia
Nieves Martinez Lago ... @DraMartinezLago
3K Followers 3K Following Medical Oncologist & Clinical Researcher | Gastrointestinal Oncology · Neuroendocrine Tumors · Sarcomas | Real-World & Translational Research | @oncomet_
NET CONNECT powered b... @net_connectinfo
1K Followers 559 Following COR2ED brings you Independent Medical Education developed by NET CONNECT, international experts in neuroendocrine tumours.https://t.co/X1u06YqRt7
Lisa Yen @lisayentwin
817 Followers 613 Following Director of Programs/Outreach, Neuroendocrine Cancer Foundation @NCFCancer (formerly @LACNETS); NP Hospitalist turned NET caregiver+pt advocate. Tweets mine
Cure GI Cancers @RueschCenter
4K Followers 3K Following Fighting a Smarter War on Cancer at the Otto J. Ruesch Center for the Cure of Gastrointestinal Cancers at Georgetown Lombardi Comprehensive Cancer Center.
Akshit Chitkara, MD @chitkaramd
187 Followers 234 Following Hematolgy-Oncology🦀Fellow at @KimmelCancerCtr TJU 2024-27 Former IM Chief Resident @UCRiverside Former California Med. Asso., Resident & Fellow Delegate
SignifyMD @SignifyMD
172 Followers 603 Following SignifyMD makes expert medical insights accessible and actionable for today’s oncologists and HCPs. #Oncology #Cancer #MedTwitter
ALFONSO DUEÑAS GONZA... @duenas_gon28
2K Followers 7K Following Oncólogo Clínico e Investigador en Cáncer | Clinical Oncologist & Cancer Researcher Enfoque en Oncología Integrativa | Focus on Integrative Oncology Oncología
Jodi Perez @PerezJodi2
50 Followers 273 Following Pfizer, US Vice President Precision Medicine/Lung Franchise, wife, mother, veteran.. working to bring breakthroughs to change cancer patients’ lives
Jinesh Gheeya, MD, Ph... @JineshGheeya
1K Followers 2K Following Thoracic medical oncologist @OSUCCC_James | clinical trialist | ICI and cell therapy | s/p @UCDavis @NIH @RWJMS @UTHIMRES
Erin Stella Sullivan ... @ErinSullivanRD
1K Followers 3K Following Lecturer in Nutritional Sciences @ KCL - Oncology & Body Composition Researcher - HCPC/CORU Registered Dietitian - Former IRC EPS Postdoc Fellow *Views my own*
Cardinale B. Smith @cardismith
1K Followers 493 Following Medical oncologist, palliative medicine physician, health services researcher. Working to improve the quality of care for patients with cancer.
Zunairah Shah @ZunairahShah
2K Followers 3K Following Hem/Onc fellow @Roswellpark, @UBuffalo 🦬| Works in @Kabrajilab 👩🏻🔬🔬| Former Chief Resident |Breast Oncology| Kindness 🌸
Arif Akyildiz @Arif_Akyildiz_
323 Followers 574 Following MD, Medical Oncologist I Research Fellow @MDAndersonnews @Hacettepe University Cancer Institute. @MD Anderson Cancer Center
Ana M. Walton, ODS-C @AnaWaltonODS
611 Followers 1K Following Oncology Data Specialist-Certified | Cancer Registry Data | AI KACI NeuralFrame | METRIQ | CRStar | Epic | Cerner | ATHENA | ONCOLOG | CNExT
Hans Rueffert @hanscooks
853 Followers 2K Following Chef with no stomach, gastric cancer survivor/advocate, half-kraut, keeper of random facts, host of the But I Digest podcast. Always happy to help
WeTrials @WeTrialshub
2K Followers 2K Following Simplify your clinical trials journey with WeTrials. Get tailored matches, expert support, and advanced treatments. Download the app to enroll today!
Amit Chowdhry, MD, Ph... @amit_chowdhry
694 Followers 1K Following GI/CNS Radiation Oncologist @AdventHealth Orlando. @RocMSTP Grad w/ PhD in Statistics from @statsROC. Research: Clinical Trials, Meta-Analysis, AI
Triage Cancer @TriageCancer
2K Followers 2K Following Non-profit dedicated to providing quality info on all cancer survivorship issues & helping people triage those issues! Run by @CancerRights & @CancerAttorney
Erman Akkus @Erman_Akkus
7K Followers 926 Following MD, medical #oncology, internal #medicine, @AnkaraUni, Sharing & discussing on #cancer 💊 🧬 #GI oncology
Thomas LeBlanc, MD, M... @tomleblancMD
5K Followers 2K Following Patient experience & cancer outcomes researcher | Leukemia & palliative care doc | Chief PX and Safety Officer @DukeCancer | Tweets are mine alone.
Reetu Mukherji, MD @ReetuMukherjiMD
280 Followers 211 Following GI Medical Oncologist, Assistant Professor, Medstar Georgetown University Hospital
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