Everton G Capote Ferreira @toongo
Postdoc Scientist at 2Blades Group - The Sainsbury Laboratory. Combining data science and biology to explore how plants and microbes interact. Norwich - UK Joined January 2010-
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Everton G Capote Ferreira retweeted
1/10 🚨Preprint! One RING to rule them all (phages)👑💍⚔️ Bacteria build giant DNA-scaffolded RNase rings (larger than the ribosome!) to shut down viral infection🧬🧵👇 🔗biorxiv.org/content/10.648…
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Everton G Capote Ferreira retweeted
🧬 Thrilled to share our latest @biorxiv_micrbio preprint! Here we find that Retron-IX build crazy supramolecular rings scaffolded by DNA molecules that sense phage infection!🤯 biorxiv.org/content/10.648… Read more below🧵! (1/16)
Everton G Capote Ferreira retweeted
AF-CALVADOS: AlphaFold-guided simulations of multi-domain proteins at the proteome level onlinelibrary.wiley.com/doi/10.1002/pr…
Everton G Capote Ferreira retweeted
Potato StRWA2 recruits StSNIPER2 to destabilize NLRs, exposing a susceptibility module in late blight infection #PotatoLateBlight #NLRImmunity #DiseaseResistance @OxfordJournals Details: doi.org/10.1093/hr/uha…
Everton G Capote Ferreira retweeted
New Article: "Epigenetic regulation of TaFIP phytocytokine clusters confers basal resistance via receptor kinase TaFIPR in wheat" rdcu.be/ftehA Epigenetically regulated expression of FIP peptides upon pathogen challenge enables their perception by the receptor FIPR.
Everton G Capote Ferreira retweeted
De novo designed bifunctional proteins for targeted protein degradation biorxiv.org/content/10.648…
Everton G Capote Ferreira retweeted
Two atypical resistance proteins confer plant resistance to Melanaphis sorghi in sorghum #research #PlantCommunications cell.com/plant-communic…
Everton G Capote Ferreira retweeted
AlphaFold-based modelling lets us visualise these N-terminal “safety caps” and predict how they interfere with formation of the pore-forming resistosome. science.org/eprint/ZRZJZCE…
These N-terminal caps could be quite handy to prevent/dampen NLR autoactivity when engineering new immune receptors. Great collaboration with Suomeng Dong's lab (Nanjing) and @amiralito_ (TSL), @EnochYuen @TarhanEI @Freddie_King00 @Nickeilmann (ICL)
Everton G Capote Ferreira retweeted
VAR review complete. Egypt’s goal is disallowed because of this foul. ⚽️
Everton G Capote Ferreira retweeted
Membrane protein solubilization and structure determination using de novo–designed proteins | Science science.org/doi/10.1126/sc…
Everton G Capote Ferreira retweeted
🧬 Two new ways to explore PPI screens in LIVIA: • cLIP — which residues each partner uses • PPI Network Builder — your interactome as an interactive map 🧵👇
🚀 New tool out! LIVIA (Local Interaction Visualization and Analysis) — a browser-based tool for assessing and visualizing predicted protein-protein interactions. Drop in a prediction from AlphaFold-Multimer, AF3, ColabFold, Boltz-1/2, Chai-1, or OpenFold3 (ZIP or folder,
Everton G Capote Ferreira retweeted
New preprint! Do all kinase domains have similar activation mechanisms? We steer AlphaFold2 using "transfer seeding" of known kinases to sample 8.3 ms of MD simulations via Folding@home. We find that the pathways are different and kinase-specific! Link: doi.org/10.64898/2026.…
Everton G Capote Ferreira retweeted
Oligomer disassembly activates an HEPN-containing bacterial defense system dlvr.it/TTNRz6
Everton G Capote Ferreira retweeted
BoltzMol-1: Towards Reliable Virtual Screening for Fast and Cost-Effective Hit Discovery biorxiv.org/content/10.648…
Everton G Capote Ferreira retweeted
植物のV-ATPase構造。たぶん初 Cryo-EM structure of the Arabidopsis thaliana V-type ATPase biorxiv.org/content/10.648…
Everton G Capote Ferreira retweeted
PhD position in my group for entry in October 2026. Round 3 of the @NRPBIODTP BBSRC competition. Please RT👇 biodtp.norwichresearchpark.ac.uk/projects/vanis…
Everton G Capote Ferreira retweeted
Science is retracting the September 2025 Research Article “Kinetic organization of the genome revealed by ultraresolution multiscale live imaging,” based on discrepancies between the study’s data and conclusions. All authors approved this Retraction. scim.ag/4fhtDtm
Everton G Capote Ferreira retweeted
Surface immune signaling unlocks NLR activation through mRNA alternative splicing | Science science.org/eprint/ZRZJZCE…
Everton G Capote Ferreira retweeted
Our new paper is out: surface immune signalling can unlock an NLR immune receptor through alternative splicing. In potato Rpi-vnt1.1, splicing removes an N-terminal “safety cap”, priming the receptor for resistosome assembly and defence.
Surface immune signaling unlocks NLR activation through mRNA alternative splicing | Science science.org/eprint/ZRZJZCE…
Everton G Capote Ferreira retweeted
Surface immune signaling unlocks NLR activation through mRNA alternative splicing science.org/doi/10.1126/sc…
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