Brain-Immune Communication Lab @AleksDeLab
Deczkowska (@ADeczk) Lab for Brain-Immune Communication at Institut Pasteur. Untangling how body instructs the brain (choroid plexus FTW). aleksdelab.com Joined May 2020-
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Very happy to share this recent @AleksDeLab production!
Excited to share our new preprint: “Local B cell maturation and mast cell regulation of choroid plexus function in early life” biorxiv.org/content/10.110… initiated in the lab by @LaetitiaTravier and led by the one and only @Ali_MoussaSamir
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Brain-Immune Communication Lab retweeted
A massive global review just confirmed it. Clinical trials + real-world data from 132 million people across the globe. The HPV vaccine doesn’t just reduce cervical cancer. It almost eliminates it. Yes, you read that right. Girls vaccinated before 16 have an 80% lower risk of cervical cancer. Not a small reduction. Not “maybe.” Eighty percent. The protection isn’t only for the cervix. HPV causes cancers of the anus, penis, vagina, vulva, mouth, throat - the vaccine blocks the virus before the damage ever starts. This isn’t one study. It’s Cochrane, the gold standard of independent science. They analyzed clinical trials + real-world data from 132 million people across the globe. Not pharma PR. Not a lab press release. Global. Independent. Verified. The #1 fear? Side effects. Here’s what the data says: Arm soreness? Sure. Serious complications? No evidence. Rare side effects? Same rate as unvaccinated people. Translation: social media invented the danger. Cochrane couldn’t find it. Lawsuits against HPV vaccines? Courts dismissed claims as “speculative inferences.” Translation: conspiracy theories don’t hold up under evidence. Meanwhile, cervical cancer kills 350,000 women every year. Mostly young women. Mostly preventable. We don’t need more fear. We need more vaccination. And yes - boys should get the vaccine too. HPV doesn’t only cause cancer in women. Vaccinating boys protects everyone. Some countries are on track to eliminate HPV cancers entirely. Others are falling behind because misinformation spreads faster than vaccines. That shouldn’t be our legacy. We already have the tool to end cervical cancer. Not reduce it. End it. The only thing standing in the way is fear. Science isn’t asking for blind trust. It’s showing its receipts. Stop sharing rumors. Start preventing cancer.
Brain-Immune Communication Lab retweeted
Australia just recorded zero cervical cancer cases in women under 25 - for the first time since records began in 1982. This is what happens when a country commits to HPV vaccination and screening. We protect our girls and save lives.
Brain-Immune Communication Lab retweeted
Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity: @CellCellPress cell.com/cell/fulltext/…
Brain-Immune Communication Lab retweeted
Granzyme K+ CD8 T cells slow tauopathy progression by targeting microglia nature.com/articles/s4159…
Brain-Immune Communication Lab retweeted
It’s no secret that we do our best work when it's less like work and more like a joy. That’s what we have in mind for Woodstock Night Science. The idea is to have the most fun conference possible so that good ideas flow and we all get inspired. That's needed now more than ever!
Brain-Immune Communication Lab retweeted
Pyrolysis gas chromatography-mass spectrometry reveals the presence of micro- and nanoplastics in human kidney, liver, and brain tissue samples from 2016 and 2024, with higher proportions found in the brain nature.com/articles/s4159…
Brain-Immune Communication Lab retweeted
#WeekendRead! #LipidPower! Hugues &co show @NatureComms that lymphatic endothelial cells modify cholesterol into oxysterols, blocking PPARg in intratumor macrophages & monocytes, making them more inflammatory thus potentiating anti-tumor T cell responses!! nature.com/articles/s4146…
and here is another way of explaining immune contribution to brain physiology throughout life: x.com/Ali_MoussaSami…
This is a developing brain, very spongy, soaks up immune stimuli which can promote its development in physiology but also makes it more susceptible to infections
And discuss how these routes are used for development and maintenance but become hijacked or modified in aging and pathology. Hope You enjoy it!
And it's out! The BIC lab presents our new perspective article on "Immune Control of Brain Physiology" - fresh off the press at @NatRevImmunol nature.com/articles/s4157… wonderful synergy @_marikovacs @Ali_MoussaSamir and twitterless Amaia Dominguez-Belloso.
@institutpasteur Congratulations!!!!
@PatriziLab @ccortical wow! congratulations!
Brain-Immune Communication Lab retweeted
Our latest paper on neuronal resilience. The apoptotic pathway is activated as a transient pulse in neurons even with continuous apoptotic stimulus. Neurons prepare for survival even when they activate apoptotic signaling. Congrats Keeley and others!! nature.com/articles/s4141…
Brain-Immune Communication Lab retweeted
❇️ Ce 22 octobre, l’Institut illumine ses bâtiments en vert pour soutenir le syndrome Phelan-McDermid (PMS), un trouble génétique associé à un retard du développement et à l’autisme. Les recherches sur SHANK3 ouvrent la voie à des essais cliniques prometteurs. 💚 #ShineGreen
Brain-Immune Communication Lab retweeted
Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!
Brain-Immune Communication Lab retweeted
Neuropeptide signalling orchestrates T cell differentiation @Nature nature.com/articles/s4158…
Aleks Deczkowska @ADeczk
1K Followers 594 Following Busy @AleksDeLab at Institut Pasteur || single cells and neuro-immune stuff II #newPI #firstgen #ally🏳️🌈🏳️⚧️
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