The Lab of Adaptive Immunity and Homeostasis @AndersenJT
Jan Terje Andersen, professor ous-research.no/andersen/ Oslo, Norway Joined January 2018-
Tweets1K
-
Followers2K
-
Following3K
-
Likes5K
New study out in @NatureComms! #FcRn biology-guided engineering of long-acting coagulation factor IX. @forskningsradet @Oslounivsykehus @UniOslo_MED nature.com/articles/s4146…
#Boston next week! Reach out to talk science and opportunities. #albumin #IgG #antibodies @AutheraAS @UniOslo @Oslounivsykehus @CoE_PRIMA fc-function-summit.com
Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation: Communications Biology, Published online: 12 June 2025; doi:10.1038/s42003-025-08252-zTwo orthogonal mass spectrometry… nature.com/articles/s4200…
The C-terminal end of #albumin can be cleaved, which reduces binding to #FcRn. As such, the plasma half-life drops from 3 weeks to about only 3-4 days in humans. This biology may have implications for design of the next generation of human albumin based therapeutics. @UniOslo_MED
In this review, we discuss the rise of #FcRn antagonists as a novel therapeutic class. @BioDrugsJournal link.springer.com/article/10.100… @UniOslo_MED @Oslounivsykehus
FcRn protects IgG and albumin from catabolism, transports IgG across the placenta, and regulates IgG function. Blocking or augmenting FcRn can decrease autoimmune antibodies and enhance drug delivery. Learn more in the Review Article “Neonatal Fc Receptor — Biology and Therapeutics” by James B. Bussel, MD, Douglas B. Cines, MD, and Richard S. Blumberg, MD, from @WeillCornell, the Perelman School of Medicine at the University of Pennsylvania, @BrighamWomens, and @harvardmed: nej.md/42gEZYk
New in JBC press: "Scientists' work describes an FcRn-driven mechanistic basis for induction of potent innate immune responses with a rHA-CpG conjugate design." Learn more: jbc.org/article/S0021-…
Torleif Tollefsrud Gjølberg and colleagues describe FcRn biology, and give an overview of the current clinical pipeline of FcRn antagonists in autoimmune diseases. #neonatalFcReceptor #autoimmunedisease #OpenAccess link.springer.com/article/10.100…
Talenter og reisen! Les om Simones vei fra Forskerlinja på Ullern vg skole til @unioslo@unioslo_MED @Oslounivsykehus til CEO i @AutheraAS. @ShareLabOslo @OsloSciencePark @OsloScienceCity skolesamarbeid.oslocancercluster.no/tidligere-ulle…
Listen to Careers in Discovery where @TorleifGj , CSO and co-founder of @AutheraAS takes us through the company's journey from its academic beginnings @UniOslo_MED @UiO_LifeSci and @Oslounivsykehus careers-in-discovery.podbean.com/e/torleif-gj%c…
We welcome Madicken Bildsten as a PhD student in our lab and @CoE_PRIMA🎈She will work on protein engineering strategies targeting cancer. Lab co-supervision by Nikoline Rasmussen and collaboration with the lab of @JOlweus 🔬@forskningsradet @UniOslo_MED @Oslounivsykehus
Thanks to Laura Tran from @TheScientistLLC for highlighting one of the recents scientific articles about #antibodies with pH-dependent antigen binding properties from @CAT4Science at @DTUtweet and @AndersenJT @UniOslo: the-scientist.com/ph-engineered-… Orig Article: cell.com/structure/full…
A warm welcome to our new lab member Lilli Bay! 🎈As a postdoc she will explore protein engineering strategies in the context of two favorite immune receptors; #FcRn and #TRIM21. Funded by @forskningsradet. @CoE_PRIMA @UniOslo_MED @OsloSciencePark @Oslounivsykehus
Proud of @AutheraAS and @SimoneMester_ From master's degree to PhD to CEO in 2022. Simone is one of the winners of @womentecheurope! Thank you for the support. @forskningsradet @OsloSciencePark medwatch.no/nyheter/karrie…
A seminar celebrating 🎈@DrRHatchett's honorary doctorate at @UniOslo_MED! @CEPIvaccines @CoE_PRIMA @Oslounivsykehus @Folkehelseinst @NFdep @Kunnskapsdep
@AaenKH has defended her PhD thesis “Next-generation human #albumin fusion proteins engineered for enhanced plasma half-life and therapeutic efficacy” You FIXed it! 🥊@UniOslo_MED @Oslounivsykehus @forskningsradet @CoE_PRIMA
Last week was fun 🎈 Mark Cragg in Oslo as Visiting Professor of @CoE_PRIMA. Engaging talks and discussions on immunotherapy and how to engineer #antibodies for agonism. @unisouthampton @UniOslo_MED @forskningsradet @NSImmun
On the cover of a magazine! 🎈Great collaboration with @AndreasLaustsen and the team🔬
Cool to see our article "Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling" on the cover of @Structure_CP! cell.com/issue/S0969-21… Read paper here: cell.com/structure/full…
Cool to see our article "Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling" on the cover of @Structure_CP! cell.com/issue/S0969-21… Read paper here: cell.com/structure/full…
GreiffLab 💻🔬�... @victorgreiff
5K Followers 5K Following Computational and Systems Immunology Lab @UniOslo and @Imprintlabs. Immune receptor profiling | Machine learning | Antibody engineering
Helene Knævelsrud @KnVelsrud
838 Followers 484 Following Associate Professor at University of Oslo. Cancer Researcher. Alumni of the Young Academy of Norway.
Kjetil Tasken @KjetilTasken
2K Followers 559 Following Director, Institute for Cancer Research, Oslo University Hospital; Group Leader, Dept. of Cancer Immunol; Professor, Inst. Clinical Medicine, University of Oslo
Geir Kjetil Sandve @SandveGeir
786 Followers 101 Following Professor in bioinformatics/machine learning at University of Oslo, Norway. Follow me at @[email protected] or at @[email protected]
Florian Krammer @florian_krammer
349K Followers 1K Following Viruses, viruses, viruses and vaccines. V5=3xancestral+1x bivalent+1xXBB Professor at the Department of Microbiology Icahn School of Medicine at Mount Sinai
Centre for Cancer Cel... @CanCell_UiO
899 Followers 230 Following Norwegian Centre of Excellence within @UniOslo and @Oslounivsykehus aiming to uncover and exploit the Achilles' heels of cancer.
Norges forskningsråd @forskningsradet
43K Followers 30K Following Forskningsrådet gjør grensesprengende forskning og radikal innovasjon mulig. Vi jobber for et samfunn der forskning brukes og deles. Idékraft verden trenger.
UiO - Det medisinske ... @UniOslo_MED
5K Followers 1K Following Det medisinske fakultet, UiO. Medisinsk og helsefaglig forskning, utdanning og formidling til pasientens og samfunnets beste.
Mariike Kuijjer @mkuijjer
1K Followers 714 Following Computational biology & cancer research. Associate Prof, iCAN University of Helsinki, Group Leader NCMM, University of Oslo. Find me on 🦋 https://t.co/CYJ5VJwqsH
Leo James' Lab @JamesLab9
961 Followers 230 Following Leo James' lab at MRC LMB in Cambridge, UK. Host-pathogen interactions, immunity to viruses, TRIM proteins and HIV. Account run by lab members.
Kyte Group @GroupKyte
192 Followers 63 Following
Anthony Mathelier @AMathelier
2K Followers 640 Following Computational biologist interested in gene expression regulation. Associate Director and Group Leader @NCMMnews. Follow me at @amathelier.bsky.social
Adrian Liston @LabListon
12K Followers 5K Following 🇦🇺🇧🇪🇬🇧👨🔬🌈 Professor of Pathology at @CamPathology @Cambridge_Uni. @ImmunolCellBiol Editor-in-Chief. Daddy
VignuzziLab @VignuzziLab
16K Followers 8K Following Mostly post about fitness and food in 🇸🇬 Singapore. some science lab stuff too.
Philippe A. Robert @PRobertImmodels
1K Followers 1K Following Computational Immunologist + Real-World QSP modeller
Akademiet for yngre f... @yngreforskere
3K Followers 579 Following Akademiet for yngre forskere /Young Academy of Norway - en tverrfaglig møteplass og forskningspolitisk plattform for yngre forskere. Tweets in Norwegian/English
Line Bjørge @DrLB
778 Followers 969 Following Professor in Gyn & Obst, co-director and PI in CCBIO, UiB @CCBIO_UiB INOvA @reachoutinova Medical Director, Gynecologic Oncology, Haukeland University hospital
Steven Kleinstein �... @skleinstein
2K Followers 1K Following Computational immunologist @YaleMed; B cell receptor sequencing analysis, https://t.co/IDRWEUaBIA + multi-omics signatures of infection, vaccination, autoimmunity
TaskenLab @TaskenLab
477 Followers 142 Following Tasken lab was established in 1997 at University of Oslo. Now located at Dept. of Cancer Immunology, Institute of Cancer Research, Norwegian Radium Hospital.
Åslaug Helland @HellandAslaug
359 Followers 172 Following
NAITbabies.org @naitbabies
552 Followers 436 Following #FNAIT Life threatening bleeding disorder caused by the maternal immune response against fetal platelets.
Sofia Moragues @sofiamilabs_
0 Followers 46 Following Biotechnologist, App Specialist Bridging the gap between complex NGS data and Ab discovery at @MiLaboratories
Antibody News @antibodynewshq
255 Followers 5K Following
Wjennings @Wjennings6
10 Followers 472 Following
Daniel Obinna @DanielObin23850
347 Followers 3K Following SERVING GOD PAYS THE MOST, #JESUS CHRIST IS LORD, #Auto technician, Forklift operator, Welder , Butcher. Follow me on facebook for more of God's w @danielobi555
Maria Clara Resende @mclara_resende
91 Followers 748 Following Brazilian scientist, doing my masters in Neuroscience at the Neuropharmacology lab at the University of Brasilia, Brazil.
Elisa Glomset Kjersem @Elisaglomset
1 Followers 83 Following
Razelle Kurzrock, MD @Dr_R_Kurzrock
9K Followers 7K Following Momx7 (4 children; 3 dogs); wife; Director, Center, Precision Oncology/Rare Cancers; CMO WIN; physician, not provider; CureMatch (cofounder); opinions mine
Alejosson @alejosson
0 Followers 15 Following
Mona Yazdani @mona_yazdani
8 Followers 381 Following Ph.D. of Cell Therapy, Postdoctoral Reseach Fellow @CCI_UoS, Postdoc alumni @MDAndersonNews (tweets are my own)
Archisman Bhunia @archi_741
200 Followers 6K Following #SCIENCE...the study of exceptions... adopt it...before it adapt u🧬
Bryan MCMINN @LifeofBryan4u2
293 Followers 3K Following Nearly all men can stand adversity, but if you want to test a man's character, give him power. Abraham Lincoln Semper Fidelis
Lasagna Marianela @MarianelaLasag
46 Followers 824 Following Mamá de Martu Doctora @UBA Médica Clínica @UNR Docente @FFyB
wewety33 @wewety33
7 Followers 537 Following
Susanne Stuffers @SanneStuff
241 Followers 152 Following MD PhD -- Healthcare investments, mostly early stage, with a passion for cutting edge biotech.
Cathrin DeNooyer @CathyDZen
211 Followers 8K Following
lena midtsian @MidtsianLena
58 Followers 598 Following
Serpil Özgüven @serpil_ozguven
252 Followers 3K Following
Elise Biopharma @elisebiopharma
106 Followers 2K Following CDMO | Biologics | Microbial | Mammalian | cGMP
InflationTrade🇺�... @Prouhal423
55 Followers 2K Following 15-30% Monthly | 2 High-Conviction Stocks.Short-Term Gains: 15-20% in Days/Weeks.DM "JOIN" for WhatsApp Alerts. Live Trade Signals • Market Analysis
sharan prakash @sharansherry
40 Followers 2K Following
Margarida @margaridaama
654 Followers 1K Following
Bharti From India @Bharti97528782
5 Followers 61 Following Bioinformatician: Antibody Discovery Program for vaccine development
Robin @robininge
71 Followers 229 Following
Journalases @journalases
23 Followers 575 Following Official account of ASES academic journals. Peer-reviewed, open access, multidisciplinary publications and calls for papers. Publishing in 7 fields
SOMSUBHRA GOSWAMI @SOMSUBHRAG24965
15 Followers 253 Following Ph.D Scholar, Tissue Restoration Laboratory, BSBE-MFCEM, IIT Kanpur. Master's in Chemical and Molecular Biology, IIT Kharagpur-IACS Kolkata. Ag(Hons.)BCKV,WB
william L @heny_jason
12 Followers 199 Following
Bjørn Tore Gjertsen @gjertsenbt
9 Followers 43 Following
Meriem Belhadj @meriem07belhadj
119 Followers 4K Following
Ahmed Gehad @ge58502263
6 Followers 314 Following
Johannes Beyene @beyene_joh48682
52 Followers 755 Following
Bente Halvorsen @BenteHalvo84025
20 Followers 138 Following
julia @juliagreissl
3 Followers 84 Following
Jobrigt @jospal
75 Followers 611 Following Nerdy genX parent. Enjoys ice bathing, singing and politically incorrect comedy
Forskningspolitikk @Fpolitikk
2K Followers 3K Following Nordisk tidsskrift for forsknings- og innovasjonspolitikk. Utgis av NIFU. (Nordic magazine for research and innovation policy.)
Fridrik Bertelsen @FridrikB15624
1 Followers 188 Following
Cognitive Dissident @cogdissident2
1K Followers 7K Following Subvert the repressive materialist paradigm, affirm the spiritual. I love trees. ET disclosure: Wilson/Davis notes, craft “not made by man - not by human hands”
MD. Arafat Hossain @mdarafat21729
7 Followers 364 Following Department of pharmacy at Gopalgonj science and Technology University
vaccine_clint @ClintVaccine
50 Followers 181 Following Ph.D. Student in Ivelin Georgiev's lab at the Vanderbilt Vaccine Center
Abdallh Adam @AbdallhAda4897
0 Followers 17 Following
Adam Woolfe @WoolfieParis
170 Followers 835 Following Computational biologist, long suffering resident of Paris and part time Mossad agent.
Surendra Singh @Surendr87325240
497 Followers 7K Following S/o Rajendra Singh & Grand son of #DrRamBuxSingh (Renowned and Considered as a Revered Father of Bio-gas)
Vicente Dietrich @VicenteDie55852
62 Followers 3K Following
varnali @varnali_059
87 Followers 3K Following
OncoDaily GI @OncoDailyGI
2K Followers 7K Following Your daily source for the latest updates, insights, and news in gastrointestinal oncology. #OncoDailyGI #OncoDaily #GIOncology
knut roger glesne @KnutGlesne
6 Followers 108 FollowingYou might like
