Applied Biophysics @AppliedBioPhys
Creator of ECIS® 😎 Pioneering impedance-based tools for real-time, label-free cell research and drug discovery. Study cells in vitro with precision and ease. biophysics.com Troy, NY Joined October 2017-
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New 🥳#ECIS research from the @CNSE This study used ECIS to track how NIH 3T3 fibroblasts and bEnd3 endothelial cells respond to SMA nanoparticles in real time. 📖Full study: pubs.acs.org/doi/10.1021/ac… #BiomedicalResearch #Nanotechnology #CellBiology #BarrierFunction #ECIS
Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it. With #ECIS Z-Theta, researchers showed: 🔹 NaCl cut TER 30–69% & slowed migration 🔹 L-carnitine partly rescued TER & repair 📄Full Paper: 10.1016/j.exer.2025.110499
Using #ECIS Z-Theta, researchers tracked how Müller glial EVs affect RPE barrier function: 🔵 Normoxic EVs: Barrier stable ✅ 🟡 Hypoxic EVs: Barrier weakens, TER drops over 72h 💡 #ECIS reveals how hypoxic EVs compromise retinal integrity Full paper: mdpi.com/2079-7737/14/8…
We are saddened to share that our colleague and friend, Dr. Ivar Giaever—Nobel Laureate and co-founder of Applied BioPhysics—passed away peacefully on June 20 at the age of 96. His brilliance, humor, and visionary spirit continue to inspire us. He will be deeply missed. 🕊️💙
🔎 TEERZ doesn’t just give more data—it gives better answers. 📉 Same trend as manual TEER, but with: ✅ Real-time, high-res data ✅ Full 96-well tracking ✅ Zero interruptions Why settle for snapshots when you can see the full story? #TEER #TEERZ #ECIS #CellBiology #Biotech
🧬 New #GPCR insights via #ECIS! UIC researchers show CLIC1/CLIC4 regulate Rac1 in endothelial cells—not through ion channel activity, but via structural domains (C-termini). 📖 Study: lnkd.in/giTdG6h7 🔍 About ECIS TEER: lnkd.in/gEqFH5Bt #BarrierFunction #TEER
Discover how ECIS® evolved from a bold scientific idea into a trusted tool that’s transformed live cell research for over 40 years. ⬇️Link below⬇️#ECIS 🧑🔬tinyurl.com/3kpprc6n
🧬 Calling all cell biologists & bioengineers! Join us at IBCA 2025 – the 6th Int'l Conference on Impedance-Based Cellular Assays! Register now 👇 📃lnkd.in/gi2dUQQu #IBCA2025 #CellBasedAssays #ECIS #ImpedanceAssays #CellBiology
🦠New study from Univ. of Regensburg shows how #ECIS tracks virus-induced cytopathic effects in real time—offering a powerful, non-invasive alternative to traditional neutralization assays. 🔗lnkd.in/gRcFRxcQ #Virology #VirusNeutralization #Biotech #Pseudovirus #Impedance
Want to see what #ECIS can do for your cell research? 🔗 Contact us: lnkd.in/gEqFH5Bt #SepsisResearch #EndothelialCells #BarrierFunction #RealTimeData #LungInjury #CellScience #BiotechTools
🧪 How do you track lung cell injury in real-time—without disturbing the cells? Easy. Use #ECIS. 😉 Researchers at Shanghai Jiao Tong Univ. studied sepsis-induced lung injury 🫁 and the protective power of telocyte-derived exosomes 🧬—focusing on miRNA-146a-5p & caspase-3.
📚 Full Study: lnkd.in/gJu5-JBX
Exciting new paper from Dr. A. Chowdhury & UQ @MDPIOpenAccess 🧪 Real-time venom research with #ECIS 🐍 Viper & cobra venoms cause cell damage 🛡️ DTIs (varespladib + marimastat) offer protection ⚖️ Supports alternatives to animal testing 📄 Full paper: mdpi.com/2072-6651/17/4…
Congratulations to Catherine on graduating from SBA THRIVE 🎉We’re proud of her dedication to leadership, growth, and innovation. Her fresh ideas and strategies inspire our team and drive us forward.🚀Here’s to continued success and impact! #Leadership #Innovation #GrowthMindset
Join us for our upcoming webinar: Barrier Function Assays at 11:00 AM EDT on October 15, 2024 ➡️lnkd.in/gn3qbqSb This webinar will discuss how complex impedance measurements with #ECIS can be used to evaluate the barrier function and #TEER of confluent cells.
Watch 🤩our latest video to learn more about #ECIS and follow our page for updates! If you have any questions, let us know in the comments 👩🔬 ⏩tinyurl.com/yrnnfrwd
Join us for our upcoming webinar: Automated Cell Migration at 11:00 AM EDT on October 1, 2024 ➡ tinyurl.com/4a5dw93u This webinar will discuss how the #ECIS system employs electric signals to both wound and monitor the healing process of cells. #sciencetwitter
Join us for our upcoming webinar: Cell Invasion/Extravasation Assays @ 11:00 AM EDT -September 17, 2024 ➡ tinyurl.com/mtchyfya Topic: Observe the extravasation of cell layers in real-time and record quantitative data regarding the metastatic potential of the cancer cells.
We are excited to announce we have received a 2-year, $1.8M grant from NIH! 🥳 tinyurl.com/mt7ua5cp The SBIR grant will fund the R&D of the #ECIS Cell Assurance Monitor, a new approach to ensure the quality and integrity of cells grown in vitro. 👩🔬🧫
Congrats to our company President, Catherine, for being accepted into the SBA T.H.R.I.V.E. CEO Training Program! She is excited about this opportunity to collaborate with local business owners and learn from business leaders nationwide🥳Huzzah! #smallbiz @ThriveSBA @SBAUpstateNY
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