Beckmann Lab @BeckmannLab

No longer updating this account. Find us @beckmannlab.🦋.social genzentrum.uni-muenchen.de/research-group… München, Bayern Joined April 2018

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Antonio J. Pierik @AJPierik

a year ago

Read Rosales-Hernandez et al. doi.org/10.1038/s44318… and Zerbes/Colina-Tenorio et al. doi.org/10.1038/s44319… to find out about delivery of the Rieske protein after Bcs1 transport to Mar26 and MICOS for bc1 complex assembly.

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Beckmann Lab @BeckmannLab

2 years ago

Our results finally explain the essential role of snR30 snoRNA! Check out the details in our preprint to find out more 👉👉👉 biorxiv.org/content/10.110… #ribosome #cryoEM #RNA

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Beckmann Lab @BeckmannLab

2 years ago

First structure of a H/ACA snoRNP acting in ribosome synthesis. In a great collaboration with the Hurt lab, we provide a detailed structural and biochemical view of the snR30 snoRNP guiding local 18S rRNA subdomain folding. 👇👇👇

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Nature Communications @NatureComms

2 years ago

Authors including @jingdongcheng report cryo-EM structures revealing how antibiotic tigecycline can also target human mitoribosome. nature.com/articles/s4146…

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Beckmann Lab @BeckmannLab

3 years ago

Also check out the paper by @zeqiraj and @YKulathu: nature.com/articles/s4158…

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Beckmann Lab @BeckmannLab

3 years ago

Check out the the full story here: nature.com/articles/s4158…

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Beckmann Lab @BeckmannLab

3 years ago

Fresh out of the oven, our collaboration with the Kopito Lab - UFL1(E3) modifies, binds to, and dissociates the 60S subunit from the Sec61 translocon! #ribosome #cryoEM

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Beckmann Lab @BeckmannLab

3 years ago

@IsraelF96135088 Negroni?

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Beckmann Lab @BeckmannLab

3 years ago

@petesoi1 @ERC_Research @CEITEC_Brno Congratulations Petr, all the best!

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Beckmann Lab @BeckmannLab

3 years ago

For a more detailed look, check out the paper now👉 nature.com/articles/s4146…

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Beckmann Lab @BeckmannLab

3 years ago

Otu2 can bind to 40S during cytoplasmic ribosome biogenesis and all stages between ribosome recycling and start-codon recognition, but becomes a highly specific enzyme for translational reset during recycling/(re)initiation by removing mono-ubiquitin present on eS7.

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Beckmann Lab @BeckmannLab

3 years ago

🎉We are thrilled to share our exciting new collaboration with @inada_lab and @jingdongcheng on how Otu2 recognizes and deubiquitinates 40S ribosomes after translation. Here is a thread with the most interesting findings:👇 #ribosome #ubiquitin #cryoEM

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Green Lab @GreenLabJHMI

3 years ago

Turns out MutS2 just doesn’t cut it ✂️ despite it having an SMR domain! Our latest collaboration with the @BeckmannLab characterizing the role of MutS2 in splitting stalled ribosomes in B. subtilis. biorxiv.org/content/10.110…

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Jingdong Cheng @jingdongcheng

3 years ago

Let's rotate! Thanks to the great Hurt lab and @BeckmannLab, our story on the 60S ribosome biogenesis is finally out in EMBO reports. We find the 5S RNP in a new rotate conformation when stably incorporate into the nucleolar pre-60S. #cryoEM #ribosome doi.org/10.15252/embr.…

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QMB Munich @MunichQbm

4 years ago

Its online:🥳🎊🎉 Check out the @MathWorksAI user story🍻 de.mathworks.com/company/user_s… about our (@BeckmannLab, @hopfnerlab) DL based Cryo-EM image analysis tool (nature.com/articles/s4159…). Thank you @MathWorks for the great support!👍👍

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Beckmann Lab @BeckmannLab

4 years ago

Check the full story here 👉🏻👉🏻👉🏻nature.com/articles/s4146…

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Beckmann Lab @BeckmannLab

4 years ago

The Ski2-like helicase 1 subunit applies a pulling force on the mRNA which causes RQT to swivel between two conformations. This leads to the destabilization of the 40S subunit, resulting in subunit dissociation of the leading ribosome.

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Beckmann Lab @BeckmannLab

4 years ago

Keeping up the momentum, we're excited to share the final version of our story about RQT-driven ribosomal splitting 🎉 🎉 Shout out to @KaBe__01, @ThomasB08006066, @inada_lab and everyone involved! Read on to learn more👇🏻👇🏻👇🏻 #cryoEM #ribosome #RQT

Beckmann Lab @BeckmannLab

5 years ago

Pull the ripcord to clear the traffic jam: RQT splits collided #ribosomes by engaging the emerging mRNA. Check out our new story at #bioRxiv: biorxiv.org/content/10.110…