Cristian Coarfa @CCoarfa
Associate Professor, Bioinformatics, Dan L Duncan Cancer Center, Center for Precision Environmental Health, Baylor College of Medicine Houston, Texas Joined October 2019-
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Congratulations, @ARodCastro, @CCoarfa PIs, awarded an R01 grant to advance #research on #LungRegeneration and #PulmonaryFibrosis! @bcmhouston @BCMDeptMedicine @BCMCancerCenter
Reflections on the current state of the art in #RenalMedullaryCarcinoma management and therapeutic targets on our way to improve median survival to 5 years by 2030: tandfonline.com/doi/full/10.10… #EndRMC @renalmedullary #Kidneycancer
Congratulations Dr Powell @hannpowell96 and to her dedicated mentor @Kaochar2 !
Our newly minted Dr. Powell!! @hannpowell96 It has been a true honor to be part of your journey and to watch you grow into the remarkable scientist you are today. Congratulations on this tremendous achievement! #ProudPI I am deeply grateful for our exceptional lab family, whose
Winnie (Ngan Fung) Li et al. reveal how macrophages mount a defense against HuNoV by phagocytosing infected cells — check out our latest findings! 👇 journals.asm.org/doi/10.1128/mb… @NganFungLi @bcmhouston @BCMFromtheLabs @CCoarfa @OrganoidDiva @sash_ramani
.@ARodCastro, @MJSeasock, @CCoarfa et al identified a protein, #Let7, that keeps #pulmonaryFibrosis in check. @bcmhouston @BCMDeptMedicine @NatureComms @BCMGradSchool blogs.bcm.edu/2025/05/20/fro…
Tremendous progress @AlanWaich4 !
🌉 Wrapped up #ATS2025 in SF! Thrilled to present our research on spatially defined transcriptomic signatures in early ILD. Huge thanks to @ivanorosas & our @bcmhouston @BCMDeptMedicine @BCMFromtheLabs team for their support! @ATS_RCMB @atscommunity
.@ARodCastro, @MJSeasock, @CCoarfa et al identified a protein, #Let7, that keeps #pulmonaryFibrosis in check. @bcmhouston @BCMDeptMedicine @NatureComms @BCMGradSchool bcm.edu/news/let-7-is-…
Great study @MJSeasock and @ARodCastro ! Grateful for the opportunity to contribute
(1/n) Our article is out in @NatureComms! We set out to examine the contribution of the Let-7 microRNA over alveolar type 2 (AT2) stem cell plasticity in genesis of pulmonary injury and fibrosis in work led by @MJSeasock and Shafiq in my lab. Paper: rdcu.be/elun3 👇
This is an amazing paper from the groups of @anshulkundaje & Scott Boyd and an example of how AI can be used well in biology. Basically, they are able to predict disease status (e.g. lupus, Covid, HIV, influenza) from BCRseq and TCRseq. I think this has great implications.
Today, in collaboration w/ colleagues at the Institute of Science and Technology Austria (ISTA), we report the first-ever method for using light microscopy to comprehensively map all the neurons & their connections in a block of mouse brain tissue. More →goo.gle/4maUNUs
Thank you @naliphd for this exciting collaboration on inflammasome activation in heart failure. This article, among many strengths, follows up very creatively and convincingly on cell-cell communication alterations inferred using scRNASeq data @BCMFromtheLabs
Better late than never — our paper revealing that fibroblast NLRP3 activation promotes atrial myopathy and diastolic dysfunction is now out in #JACC: Basic to Translational Science! sciencedirect.com/science/articl… 🤝@CCoarfa @StanleyNattel #DobromirDobrev
Impactful work with the @PavlosMsaouel lab, based on epigenomic and transcriptomic integration. We know that science is beautiful, and when editors pick our figures for cover it it further confirms it 🫶
👇The @CCR_AACR cover below is a #RenalMedullaryCarcinoma cell expressing MUC16 (CA-125) in green and actin red with overlapping regions in yellow. Photo taken by Menuka Karki #MsaouelLab and also featured in our art contest led by @ED_PhD_ Full article: aacrjournals.org/clincancerres/…
Highly recommended!
Interested in single cell genomics but need help getting started? Check out my lab's Single Cell Genomics Day on April 25. Talks will feature recent exciting computational and experimental advances and will be live-streamed at satijalab.org/scgd. Please RT/spread the word!
Congratulations to our #GIresearch symposium poster contest winners! 🥇 Luqiong Wang, @bcmhouston 🥈 Lauren Lynch, Baylor College of Medicine 🥉 Sohini Banerjee, Baylor College of Medicine It was close competition! We're lucky to have so many scientists at our institutions 🤠
CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation out on Clinical Cancer Research aacrjournals.org/clincancerres/… This study explores potential biomarkers 🧬for early detection and disease monitoring of renal medullary carcinoma (RMC), a highly aggressive cancer primarily affecting young individuals of African descent with sickle cell trait🔬. Researchers performed integrated profiling of RMC tumor tissues and identified MUC16, the gene encoding cancer antigen 125 (CA-125), as significantly upregulated in RMC. Elevated serum CA-125 levels were observed in 66% of RMC patients and correlated with metastatic tumor burden. Functional studies demonstrated that restoring SMARCB1, a key tumor suppressor lost in RMC, reduced MUC16 expression. These findings suggest that CA-125 could be a valuable biomarker for disease monitoring and treatment targeting in RMC. #KidneyCancer @KyleBlumMD @JPBertok @DurgaNandTripat @JustinLebenthal @rahulshethmd @priyaraomd @LabGenovese @lazcano_rossana @ALazarMDPhD @CCoarfa @PavlosMsaouel @OncoAlert 🚨
Very grateful to see this study published, and also grateful for our collaboration with @PavlosMsaouel lab ! Next, an even deeper dive into the epigenetics of RMC
@OncHahn @andrewjohnsmd @ERPlimackMD @crisbergerot @NazliDizman @BradMcG04 @IamLinghua @rahulshethmd @MikeSerzanMD @kaydaustin @LabGenovese @OAlhalabiMD @perelli_luigi @DrJeffreyGraham @ChadTangMD @salvolarosa @TiansterZhang @d_shapiro1 @QingZhangLab @Daniel_J_George @priyaraomd @UroDocAsh @ChapinMD @drmehrarohit @LisaHenske @DrDanielHeng @ED_PhD_ @DanielFrigo @rovingatuscap @katy_beckermann 5/5 This study establishes CA-125 as a clinically relevant biomarker for RMC, enabling non-invasive disease monitoring. Future directions include exploring MUC16-targeted therapies, and combiningCA-125 with ctDNA for precision tracking. #endRMC #CancerBreakthroughs
@OncHahn @andrewjohnsmd @ERPlimackMD @crisbergerot @NazliDizman @BradMcG04 @GGiannarini @mjmoussa_ @PauloBergerot @SGoswamiMDPhD @LabGenovese @OAlhalabiMD @ZiadBakouny @DrJeffreyGraham @ChadTangMD @salvolarosa @TiansterZhang @d_shapiro1 @QingZhangLab @DrDanielHeng @priyaraomd @UroDocAsh @ChapinMD @drmehrarohit @LisaHenske @ED_PhD_ @DanielFrigo @rovingatuscap @katy_beckermann @HindRafei 5/5 All figure data are available in the manuscript page & the scRNA sequencing at the GEO webpage: ncbi.nlm.nih.gov/geo/query/acc.… Visualization and real-time interrogation will be made available in the coming months through our Single Cell Research Portal: singlecell.mdanderson.org
Great stuff @AyeshaShafi_PhD 👏
Elevated CBP/p300 expression linked to poor outcomes in advanced #ProstateCancer. @AyeshaShafi_PhD @CPDR_Labs joins @AndreaMiyahira @PCFnews to discuss AR coactivators CBP/p300 in prostate cancer and research revealing that CBP/p300 expression increases as prostate cancer
From the Labs at Bayl... @BCMFromtheLabs
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BCM Department of Med... @BCMDeptMedicine
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Acquired Resistance t... @NCIARTNet
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AntonyRod. (microRNA ... @ARodCastro
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TMC Digestive Disease... @tmcddc
210 Followers 392 Following Official account of the Texas Medical Center Digestive Diseases Center Core. Federally funded (P30DK056338), supporting digestive diseases research in the TMC!
Texas Region Biotech ... @TXBionetworks
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Enrico R. Barrozo @BarrozoPhD
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46 Followers 309 Following Brain Cancer Researcher at MD Anderson Cancer Center, Houston, USA Native, Morena, MP, India https://t.co/RvyZiMKhFu
From the Labs at Bayl... @BCMFromtheLabs
6K Followers 6K Following From the Labs at Baylor College of Medicine spotlights the newest and most interesting research information from the bench at the College.
Salma Kaochar @Kaochar2
2K Followers 2K Following Assistant Professor in Houston, TX. Interested in cancer biology, drug development, biomarkers. My views are my own. Also at https://t.co/THsDnOWQ4l
EllisLab_ @EllisLab_
4K Followers 4K Following Center for Prostate Disease Research @cpdr_labs @nciccr_gmb - trying to learn something new everyday - tweets=mine 🇦🇺
Peggy Goodell @Goodell_Lab
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Prostate Cancer Found... @PCFnews
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Oded Rechavi @OdedRechavi
146K Followers 1K Following Transgenerational inheritance, q.e.d: @qedscience https://t.co/tKNk6qiSlZ TED: https://t.co/rcOm9TSTf5 Huberman Lab Podcast: https://t.co/xZTNlx9nbi
PCF Science @PCF_Science
5K Followers 647 Following The official Twitter account for scientific news from the Prostate Cancer Foundation. Follow us at @PCFNews @ https://t.co/CB3q1YYabC
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Keiran Smalley @LabSmalley
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48K Followers 0 Following Automatically tweets new posts from https://t.co/A8uFi473gj Please respond in the comment section of the blog. Old posts spool at https://t.co/HLEEe8oMCd
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Emily @aelahsarcino
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352 Followers 758 Following Bioinformatician by profession. Geek by nature. Passionate about programming and linux.
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BCM Department of Mol... @bcmgenetics
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443 Followers 462 Following Assistant Professor starting at the Center for Advanced Biotechnology and Medicine at Rutgers. @dirienzilab
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265 Followers 369 Following Immunology PhD student @UMBaltimore. Views are my own. Interest include global health, science, statistics & languages. RPCV Ghana 16-18, TCK Mexico 96-11.
Rose Albert @rosemalb
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Taotao Tan @doubleTaoTan
129 Followers 505 Following bioinformatics & statistics. interested in multi-omics and genetics. 3rd year grad student @bcmhouston
Francesca Polverino @FrancyPolverino
1K Followers 185 Following MD, PhD | COPD Researcher & Advocate 🫁 | American Lung Association Spokesperson | Fitness Enthusiast | Views are my own.
Leo Schalkwyk @leo_schalkwyk
292 Followers 466 Following
Albert Vilella @AlbertVilella
24K Followers 23K Following Next-Generation Sequencing, Single-Cell and Spatial Biology, Next-Generation Proteomics, Synthetic Biology, Liquid Biopsy, Accelerated Compute in Biotech.
Patrick Maclean @maclean_pat
57 Followers 860 Following Junior doctor spending time in the lab Oxford / Melbourne
Shalek Lab @shaleklab
3K Followers 120 Following Alex K. Shalek Lab @MIT/@ragoninstitute/@broadinstitute/@harvardmed/@MGH_RI. Genomics, immunology, systems biology.
Peng Gao @penggaos
788 Followers 539 Following Assistant Professor @HarvardChanSPH. Interested in the #Exposome and #Multiomics. 🏳️🌈
Olorunfemi Ayeotan �... @Ayeotanfemi
484 Followers 5K Following PhD Student @katztemplemed| Cancer Researcher | Writer | Pianist | Medical Laboratory Scientist. #CRC #DNA methylation, #Disparity, #OMPs
Mayar Al Mohajer, MD ... @MayarAlmohajer
1K Followers 2K Following Professor @BCMHouston; Chief of ID @StLukesHealthTX. Passionate about IP/AS/QI (he/him)
Santiago Carrero MD @carrero95
137 Followers 1K Following I'm a physician-scientist ,passionate about Global Health and ID, love technology and Science.
Mihalis Lionakis @LionakisLab
1K Followers 514 Following Physician-scientist #NIAID @NIH | #Immunology | #innate immunity | #Immunodeficiency | #Fungi | #Infection | Father | 🇬🇷🇺🇸 | Views are mine, not of US govt
Kevin Pruitt, Ph.D. @Dr_Kevin_Pruitt
734 Followers 247 Following Associate Professor | UNC Chapel Hill | Lineberger Comprehensive Cancer Center | Pharmacology Department | UT-Austin, UNC, & Johns Hopkins alumnus.You might like
