Ceron Lab @CeronLab
Using the nematode C. elegans to investigate human diseases and enjoy science. Tweets all come from Julián Cerón, PI of the group. Also🎙 in @raticosde100cia ceronlab.com Barcelona, España Joined September 2017-
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Ceron Lab retweeted
🏳️🌈Una bandera que reflejamos en cada laboratorio, en cada proyecto y en cada persona… ¡𝘆 𝗰𝗼𝗻 𝗺𝘂𝗰𝗵𝗼 𝗼𝗿𝗴𝘂𝗹𝗹𝗼! En el @IBV_CSIC trabajamos cada día por una ciencia diversa, inclusiva y libre💙 #IBVCSIC #Orgullo2026 #CienciaInclusiva
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Meritocracia 🙏
Pablo Jarillo-Herrero, físico del MIT y Premio Fronteras del Conocimiento en Ciencias Básicas de la Fundación BBVA, explica cómo España puede atraer talento internacional 📹 Alberto Di Lolli
This work is the result of a grant from @PpccSalud with the fantastic collaboration of teams led by @nstroustrup1 at @CRGenomica, Rafael Pulido at @biocrucesHRI, @Olmedo_lab at @unisevilla, Victor J. Cid at @unicomplutense and @MfPez at @IBMB_CSIC @gusaneros1
(3/4) 🪢 The functional impact of secondary mutations on PTEN variant outcomes (4/4) 👩 🧔♂️ 👱♀️ 🧑🦰 Inter-individual variability among isogenic animals with identical mutational landscapes, studied using single-worm RNA-seq
🔥New Preprint from our lab @idibell_cat @IBV_CSIC 📢In vivo functional classification of PTEN variants reveals context-dependent oncogenicity and interindividual variability biorxiv.org/content/10.648…
Ceron Lab retweeted
Nice overview of one of the most amazing animals on Earth! @gusaneros1 @annajuanroch @AMV_REDOX @raticosde100cia @IISLaFe From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS pnas.org/doi/10.1073/pn…
Ceron Lab retweeted
Time to get ready for the Spanish Worm Meeting!! swm2026.com
We are geting closer to the deadline!! swm2026.com Register yourself, guys! Worms are one of the coolest creatures on Earth @ehuntingtones @AsociacionAVAEH @FEDER_ONG @LluisMontoliu
Ceron Lab retweeted
El pasado lunes recibimos a Gary Ruvkun, Premio Nobel de Medicina 2024, invitado por @PremiosReiJaume en el @IBV_CSIC Conoció a personal, IPs y estudiantes, compartiendo experiencias y consejos científicos. ¡Gracias a todos los participantes! 💙 #IBVCSIC #Ciencia #Nobel
Ceron Lab retweeted
We are geting closer to the deadline!! swm2026.com Register yourself, guys! Worms are one of the coolest creatures on Earth @ehuntingtones @AsociacionAVAEH @FEDER_ONG @LluisMontoliu
Ceron Lab retweeted
Come on guys and girls! We're getting closer to the deadline for the one and only, awesome, incredible, and amazing X Spanish Worm Meeting in the lovely city of Valencia! swm2026.com
Pues así sigue el asunto. Proyecto de tecnologías #CRISPR parado 4 meses porque van muy liados. Esta es la triste realidad @DianaMorantR . La burocracia son plomos atados al cuerpo que nos dificultan mucho producir y competir, aunque sea con mucho menos presupuesto. Agotador 🥵
Solicitado a principio de Febrero a la @AgEInves el cambio de los fondos de un proyecto del @CienciaGob de un centro a otro por mudanza del laboratorio, y aún estamos esperando contestación. 4 meses con el proyecto parado por una burocracia y administración que no se entiende.
Ceron Lab retweeted
🧬 Compact CRISPR nucleases are small — but often slow to activate. A new strategy just fixed that. New preprint from Liu Junjie lab (Tsinghua): fusing ATPase DnaA to PlmCas12e (CasX) via a rigid N-terminal linker overcomes the conformational activation barrier. ⚡ 1.34× average editing boost across 7 endogenous loci in HEK293T 📈 More effective genome targets detected by GenomePAM/GUIDE-seq 🔬 MD simulation: single free-energy basin vs. rugged landscape in WT ❌ ATP hydrolysis mutant: activity drops below wild-type — mechanism confirmed Liu lab, Tsinghua | Preprint doi.org/10.65215/LTSpr… #CRISPR #Cas12e #CasX #ProteinEngineering #GeneEditing
Ceron Lab retweeted
📢 ¡𝗢𝗽𝗼𝗿𝘁𝘂𝗻𝗶𝗱𝗮𝗱 𝗽𝗿𝗼𝗳𝗲𝘀𝗶𝗼𝗻𝗮𝗹 𝗲𝗻 𝗜𝗕𝗩-𝗖𝗦𝗜𝗖! Vacante para Investigador Distinguido en inmunología, identidad celular y biología computacional con IA. 🔒Posición permanente y start-up package. 👉Más Info en: call.valer-f.es #ibvcsic
Ceron Lab retweeted
🧬 CRISPR evolution — directly inside human cells — for the first time. PNAS: CRISPR-MACE uses adenovirus replication to continuously mutate, select, and amplify Cas9 variants in human cells, bypassing bacterial evolution limitations. Key results: 🔑 "Gatekeeper" G12D mutation: 3× higher DNA affinity 💪 DVKIH 5-mutant variant: ~1000× anti-CRISPR resistance ✅ Validated in CASFISH imaging — brighter, stronger signal Shoulders & Choudhary labs, Broad Institute | PNAS doi.org/10.1073/pnas.2… #CRISPR #DirectedEvolution #Cas9 #GeneTherapy #Broadinstitute
Ceron Lab retweeted
@CeronLab @AgEInves @CienciaGob La burocracia es una lacra en todos los aspectos. Pero en el campo de la ciencia, va a acabar con ella...
Ceron Lab retweeted
The round table featuring all speakers and moderated by Francisco Martin and Marcello Maresca was a great brochure for the session on the novel Gene Editing Tools. @GeneHumdi #Granada2026 #AnnualMeeting @genyo_pts
Ceron Lab retweeted
We are back at @GeneHumdi #Granada2026 #AnnualMeeting with a session focussed on new tools for the advancement of #GenomeEditing at @genyo_pts with support of @FProgresoysalud
Ceron Lab retweeted
@GeneHumdi @CeronLab Closing the session, two short talks: First Araceli Aguilar @genyo_pts presents "A novel dual-guide CRISPR–Cas13 strategy for enhanced SNV detection" with clear implications to improve diagnostic use of CRISPR tools.
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