David Penton @DavidPentonR
Physiologist and a lot more e-phac.uzh.ch/en.html Zurich; Switzerland Joined April 2018-
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David Penton retweeted
Congrats @bakhta_f for this amazing work that I have the pleasure to present today! Our new models of Primary Aldosteronism will be useful tools to better understand the disease and to test new therapeutic approaches in the future! @ENSAT_news @goharmonisation @AldolabZ
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David Penton retweeted
We are delighted to announce that it is now possible to assess the functional properties of neurons (IPSC-derived, primary, organoids) using HD-MEAs at the Electrophysiology Facility of UZH. Check out our summary of the services we can offer using this technique. The e-phac team
David Penton retweeted
Hamburg news: Bridging patient observation to molecular understanding in our molecular disease board: Here revealing a multi-hit model for FSGS by Jan Czogalla @PuellesVictor and team. @HCKH_Hamburg @UKEHamburg @unihh kidney-international.org/article/S0085-…
David Penton retweeted
These kind of measurements allow us to follow network dynamics of #iPSC-derived #neurons, #cardiomyocytes, #brain #organoids, primary neuronal cultures and more. Furthermore, the high-density of electrodes provide information about action potential propagation along neurites
David Penton retweeted
First data from our HD-MEA setup at #EPHAC! Watch how primary cortical neurons (kindly provided by @SchrattL) fire synchronized bursts of action potentials as soon as at DIV9. Get in touch if you are interested in using this system with your cells. @mxwbio #neuroscience
@PAWellingMD @RickGrimmPhD Congrats Paul for this excellent work
David Penton retweeted
Automated patch clamp was originally developed for the pharmaceutical industry, but Thompson et al. repurpose it to investigate functional properties of several sodium channel variants associated with neurodevelopmental disorders bit.ly/47xrSCz #SCN2A #epilepsy
David Penton retweeted
Calcineurin regulates aldosterone production via dephosphorylation of NFATC4: buff.ly/3KaB6uu #Endocrinology #Metabolism
David Penton retweeted
Out now: Calcineurin regulates aldosterone production via dephosphorylation of NFATc4 insight.jci.org/articles/view/… @DavidPentonR @UZH_en @UniBasel_en
David Penton retweeted
#aldosterone #potassium #hyperkalemia #adrenalgland
New mechanisms to regulate aldosterone production - great work by David Penton and associates! Calcineurin regulates aldosterone production via dephosphorylation of NFATc4 asci.altmetric.com/details/150023…
@FBeuschlein Thanks @FBeuschlein. Also for your support in this journey
David Penton retweeted
New mechanisms to regulate aldosterone production - great work by David Penton and associates! Calcineurin regulates aldosterone production via dephosphorylation of NFATc4 asci.altmetric.com/details/150023…
David Penton retweeted
Why do hyperkalemic kidney transplant recipients on CNI show no aldosterone response -a question open since a 1983 Lancet paper-seems to have been mechanistically explained. Congrats, @DavidPentonR ! insight.jci.org/articles/view/… 1983 Lancet paper: thelancet.com/journals/lance…
Calcineurin inhibitors and hyperkalemia linkedin.com/posts/davidpen…
David Penton retweeted
JASN is proud to announce that applications for the 2023–2025 Editorial Fellowship Program are now open! Early career researchers with interest in basic or clinical research are encouraged to apply. For more information, visit bit.ly/JASNEditorialF… #jnltrain
David Penton retweeted
Impressive throughput from the automated patchclamp @NanionTech presented at #LS2AM23 @LS2_ICMT @LS2Switzerland And there is one just next door in Zurich! Contact the electrophysiology facility @e_phac from University of Zurich for more information.
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