Essand Lab @EssandLab

We develop novel CAR-T cells, oncolytic viruses and viral vectors to induce bystander immunity and reshape the tumour microenvironment and improve immunotherapy igp.uu.se/research/cance… Uppsala, Sverige Joined August 2023

Tweets

10
Followers

14
Following

72
Likes

9

Mohan @mohanraj9706

3 years ago

Read our recent publication in @CCR_AACR on how characteristics of #CARTcell infusion product influences treatment outcome in #lymphoma patients. Congratulations to authors @tina_saren , @EssandLab from @UU_University at @IgpUu

Clinical Cancer Research @CCR_AACR

3 years ago

A substantial fraction of patients do not have long-term clinical response from CD19 CAR-T cell therapy. Sarén et al identify characteristics of CD8+ CAR-Ts correlating with response that may be indicators for clinical outcome. bit.ly/45ShTGJ @mohanraj9706

0 1 3 1K 0

0 3 3 707 0

View Details

Tina Sarèn @tina_saren

3 years ago

Curious to know the clinical outcome of our study and how characteristics of the CAR-T infusion products may effect? Read our latest publication in @CCR_AACR ! Thank you to everyone involved in this work😍@EssandLab @mohanraj9706 #immunotherapy #CARTcell aacrjournals.org/clincancerres/…

0 3 4 338 0

View Details

Bertrand Delsuc @BertrandBio

3 years ago

I don't know if that's the only root cause of tonic signaling but great work by $ELIC researchers. Makes sense wrt $ACLX eg who don't use scFv's but D-Domains. Complementarity-determining region clustering may cause CAR-T cell dysfunction nature.com/articles/s4146…

1 4 12 3K 2

View Details

Mohan @mohanraj9706

3 years ago

Elicera Therapeutics publishes a scientific article in @NatureComms about the CAR T construct in the ELC-401 program | @EliceraTx, #cartcell, #tcell, #glioma, #cancerResearch, #cancer #celltherapy, #Immunotherapy, @IgpUu, @UU_University. nature.com/articles/s4146…

0 1 1 74 0

View Details

Essand Lab @EssandLab

3 years ago

Tonic signaling should always be considered when designing new CARs. View our paper in @NatureComms to find out how CDR regions of the CAR can effect tonic signaling and how to screen for it. Big congrats to first author @tina_saren and all co-authors.🎉 nature.com/articles/s4146…

0 1 6 141 0

View Details

DimbergLab @DimbergLab

3 years ago

Curious on how we modified blood vessels to boost immunity and treat brain cancer? 💉🧠 Our new publication is out now on @Cancer_Cell ! Big congrats to the first authors of this work, @mohanraj9706 , @AleVaccaro93 & @tiarnevdw , and to the whole team 🥳 cell.com/cancer-cell/fu…

4 21 62 8K 7

View Details

Cancer Cell @Cancer_Cell

3 years ago

Online Now: Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma dlvr.it/Sp6vzN

0 7 31 7K 4

View Details

Elicera Therapeutics @EliceraTx

5 years ago

Are you interested in the clinical use of #CARTcells and learning more about the future potential of research? @SWECARNET, will hold an Educational Day on April 27th, 2022, where our CSO, Professor Magnus Essand, will present. news.cision.com/elicera-therap…

0 1 2 0 0

View Details

Cancer Discovery @CD_AACR

3 years ago

Read this week's #ResearchWatch: AAV-Mediated Gene Delivery of LIGHT Prolongs Survival in #Glioblastoma, summarizing the work of @mohanraj9706, @AleVaccaro93, @tiarnevdw, Magnus Essand, @DimbergLab et al. bit.ly/3q5eQLg @UU_University

0 6 16 3K 1

View Details

STorM SciLifeLab @STorMSciLifeLab

4 years ago

Exciting new work from @MagnusEssand’s group published in Nat Biomed Eng. reporting how arming CAR-T cells with neutrophil-activating protein (NAP) can improve their efficacy in solid tumors Congratulations @ChuanJin @JingMa @mohanraj9706 @DiYu 👏 nature.com/articles/s4155…