Flaherty Lab @FlahertyLab
Lab of Daniel Flaherty, Ph.D. Associate Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University. flahertylab.com West Lafayette, IN Joined August 2015-
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New paper out today from @Katrina_Holly98 and Prabhakara Rao Tharra on their work on development of bacterial carbonic anhydrase inhibitors against vancomycin-resistant Enterococci. They produced an analog with oral efficacy rescuing mice in a septicemic peritonitis model.
Bacterial carbonic anhydrase inhibitors with improved PK and efficacy in VRE septicemia mouse model. #JMedChem @flahertylab @DrugDiscoveryPU @Purdue_MCMP go.acs.org/d4V
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This project in collab with Dr. Val Watts and @Purdue_MCMP grad student @tiffany_summerr has gone from hit identification to through two manuscripts. The current scaffold had solubility liabilities and we took an approach to break up the molecular planarity to improve solubility
Flaherty Lab retweeted
New ethoxzolamide analogs from @FlahertyLab show improved PK properties and efficacy in mouse model for gonococcal infection. #JMedChem go.acs.org/aDw
@Hopkins_Lab @Super70sSports Used this pen during O-chem in college. The prof would switch between dry erase marker colors and you would hear the whole class click the pens to switch colors 😂
Flaherty Lab retweeted
Covalent UCHL1 inhibitor with crystal structure and anti-metastatic properties from @FlahertyLab @WendtLab_Cancer @KesslerlabOx Read in #JMedChem here ➡ go.acs.org/8LT
@DuerfeldtLabs Awesome job to the team!
@TheRileyLab Congrats Andrew! Great news.
@AubeLabUNC Thank you Jeff. A lot of folks have supported me on this path including yourself. It means a lot.
@DuerfeldtLabs Thanks Adam! Means a lot.
I am honored to receive this title. Thank you to Chip and Jane Rutledge and to @purduepharmacy for the support!
Chip and Jane Rutledge have a history of impactful service to Purdue. The duo shares a passion for supporting early career faculty that inspired them to endow a new professorship. Daniel Flaherty is the inaugural recipient. Full story: loom.ly/kLB-aqY #pharmacysgiantleap
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