Journal of Pharmaceutical Analysis @JPharmAnalysis
With an #impactfactor of 8.9, Journal of #Pharmaceutical Analysis is the right home for your #cuttingedge #research on any aspect of #pharmaceuticalanalysis. sciencedirect.com/journal/journa… Joined March 2023-
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Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma Scientists revealed #naringenin, a natural citrus #flavonoid, inhibiting #angiogenesis and boosting anti-tumor immunity in liver cancer. doi.org/10.1016/j.jpha…
Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma Scientists revealed #naringenin, a natural citrus #flavonoid which inhibits #angiogenesis and boosts anti-tumor immunity in liver cancer. doi.org/10.1016/j.jpha…
Targeting Atf4 for enhanced neuroprotection: Role of quercetin-loaded EVs in ischemic stroke Scientists demonstrated #extracellular vesicles loaded with quercetin (#QG-EVs) offer significant #neuroprotection in stroke. #Neuroscience #Stroke research. doi.org/10.1016/j.jpha…
Trace component fishing strategy based on offline two-dimensional liquid chromatography combined with PRDX3-surface plasmon resonance for Uncaria alkaloids Scientists uncovered an innovative strategy to uncover hidden trace active compounds in #TCM. doi.org/10.1016/j.jpha…
ZFP36 promotes ferroptosis and mitochondrial dysfunction and inhibits malignant progression in osteosarcoma by regulating the E2F1/ATF4 axis Scientists revealed that #ZFP36 is downregulated in #Osteosarcoma. Overexpression inhibits tumor growth.#Cancer doi.org/10.1016/j.jpha…
Large-scale evaluation of HIV-1 DNA drug resistance testing as a robust tool for clinical decision-making: A nationwide study in China Large-scale study in China shows HIV-1 DNA genotyping is a reliable alternative to RNA testing. #HIVResearch #Virology doi.org/10.1016/j.jpha…
Validation of breast cancer as a risk factor for anxiety and depression: Insights from Mendelian randomization analysis Scientists confirmed the #breast cancer to #mental health link via #Mendelian randomization. #Neuroscience #Oncology doi.org/10.1016/j.jpha…
Mechanistic insights into honey-boiled detoxification of ChuanWu: A study on alkaloid transformation and supramolecular aggregation Scientists revealed the detoxification mechanism of honey-fried #ChuanWu. #NaturalProducts #Pharmaceutical doi.org/10.1016/j.jpha…
Real-time monitoring and in vivo visualization of acetylcholinesterase activity with a near-infrared fluorescent probe Scientists introduced #DCM-N, a near-infrared "off-on" fluorescence probe for real-time monitoring of #acetylcholinesterase activity. doi.org/10.1016/j.jpha…
RCAN-DDI: Relation-aware cross adversarial network for drug-drug interaction prediction Scientists uncovered #RCAN-DDI model using a relation-aware cross-adversarial network for #DDI prediction. #Drug safety and #Pharmaceutical doi.org/10.1016/j.jpha…
Lipidome atlas of human myometrium reveals distinctive lipid signatures associated with adenomyosis: Combination of high-coverage lipidomics and mass spectrometry imaging Scientists mapped the first lipidome of human myometrium. #Pharmaceutical doi.org/10.1016/j.jpha…
A cascade reaction nanoplatform with magnetic resonance imaging capability for combined photothermal/chemodynamic/gas cancer therapy Scientists introduced the PB@SiO₂@MnO₂@P-Arg which uses #TME triggered cascade reactions for synergistic cancer therapy. doi.org/10.1016/j.jpha…
Advanced bioanalytical techniques for pharmacokinetic studies of nanocarrier drug delivery systems Scientists analyzed the bioanalytical methods employed in the pharmacokinetics of anticancer organic nanocarrier drug delivery systems. #Pharmacokinetics doi.org/10.1016/j.jpha…
A gene set enrichment analysis for cancer hallmarks Scientists established a consensus #cancer hallmarks gene set. Analysis of 12 solid tumors reveals unique hallmark enrichment patterns, with implications for #precision medicine. doi.org/10.1016/j.jpha…
A review on the screening methods for the discovery of natural antimicrobial peptides Scientists explored how natural antimicrobial peptides (#AMPs) fight pathogens, providing a comprehensive framework for identifying AMPs. #Antimicrobial #DrugDiscovery. doi.org/10.1016/j.jpha…
A review of transformer models in drug discovery and beyond Scientists reviewed the revolution that transformers have brought in protein design, drug target identification, virtual screening, lead optimization, and single-cell data analysis.#Pharmaceutical doi.org/10.1016/j.jpha…
Repurposing drugs for the human dopamine transporter through WHALES descriptors-based virtual screening and bioactivity evaluation Scientists proposed a workflow combining #Machine Learning and virtual screening to repurpose drugs targeting the #hDAT. doi.org/10.1016/j.jpha…
An inductive learning-based method for predicting drug-gene interactions using a multi-relational drug-disease-gene graph Scientists uncovered a novel inductive learning model for predicting unseen drug-gene interactions (#DGIs). #Pharmaceutical doi.org/10.1016/j.jpha…
Quantifying compatibility mechanisms in traditional Chinese medicine with interpretable graph neural networks Scientists presented an interpretable #GraphAI framework to decode the complex mechanisms of Chinese herbal formulas. #Pharmaceutical lnkd.in/eG_tcD4x
HyPepTox-Fuse: An interpretable hybrid framework for accurate peptide toxicity prediction fusing protein language model-based embeddings with conventional descriptors Scientists introduced HyPepTox-Fuse: an #AI tool for accurate peptide toxicity prediction.doi.org/10.1016/j.jpha…
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