Jackson Ridges @JacksonRidges
PhD Student in the Phadnis Lab flygenetics.com Salt Lake City Joined January 2015-
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Meiotic drive has long been considered as a genetic curiosity. Genomic "footprints" suggest otherwise. Check out our new review doi.org/10.1093/molbev…, a cross-taxa synthesis arguing that recurrent drive is a pervasive and underappreciated force in genome evolution.
Check out our new preprint on the D. pseudoobscura SR chromosome!
Drive, suppression, and escape from suppression of a selfish chromosome biorxiv.org/content/10.110… #biorxiv_evobio
Drive, suppression, and escape from suppression of a selfish chromosome biorxiv.org/content/10.110… #biorxiv_evobio
In a new Trends in Genetics piece, @AmLarracuente and I spotlight an amazing work lead by @peiwei_chen uncovering Trailblazer—a regulatory innovation in the in piRNA pathway to suppress the meiotic driver Stellate. Check it out: authors.elsevier.com/c/1ktQOcQbJF8ya
HHMI Investigator Nels Elde (@ElEarlyBird) of @UUtah works at the crossroads of evolutionary genetics and cell biology to study one of the biggest battlefronts in science: host-pathogen interactions. Learn more about the Elde lab’s research: hhmi.news/49MaU4W
New paper led by @Yadirapga! Even though opossums have kids at 0.5 years, they still have typical male-biased mutation (though not quite as high as humans).
Low mutation rate but high male-bias in the germline of a short-lived opossum biorxiv.org/cgi/content/sh… #biorxiv_evobio
Timescales in Cell Biology
@Lewsiferase @LisaKursel @ElEarlyBird Welcome to SLC! Feel free to come visit us while you’re down here, I’d love to meet.
@peiwei_chen Congratulations Peiwei, such an incredible story!
Genome defense requires innovation in specificity factors that recognize emerging selfish genes but does it require other types of innovations? We think so! Happy to share our preprint “Escalation of genome defense capacity enables control of an expanding meiotic driver” 🧵:
Escalation of genome defense capacity enables control of an expanding meiotic driver biorxiv.org/cgi/content/sh… #biorxiv_genetic
@peiwei_chen @Nitin_Phadnis Thank you so much Dr. Chen!
Extremely cool talk by @MayaVoichek (@juliusbrennecke lab): Drosophila retrotransposons encode membrane-associated micropeptide to traffic between somatic and germ cells! #ICTE2024
Congratulations to Julius Brennecke for securing one of this year’s @ERC_Research Advanced Grants! Julius will study the arms race between transposons and host genomes. #ERCAdG More here: oeaw.ac.at/imba/research-…
@saracarioscia Never pick against UConn 😤
unidentified hybrid incompatibility locus between D. melanogaster - D. sechellia. Huge thanks to @Nitin_Phadnis for making it all possible! (2/2)
I’m happy to spend my inaugural science tweet showcasing our labs’ featured article in the current issue of @GeneticsGSA GENETICS academic.oup.com/genetics/artic…! @Jackson_Bladen, @flythecooper, and I use some clever genetics and pooled sequencing to expose a previously (1/2)
Happy to see this paper out! With @AmLarracuente, we review the implications of intragenomic conflicts mediating the co-amplification of gene families on sex chromosomes, and how this process might be fueled by sex-biased mutation. royalsocietypublishing.org/doi/10.1098/rs…
If Darwin's finches were transposons, and the Galapagos islands were the Drosophila ovary, this cool new paper is all about the diversification of their beaks!🦜Congratulations Kirsten, @juliusbrennecke and all co-authors for this tour-de-force! 🥳👏 biorxiv.org/content/10.110…
I'm thrilled to share that our work on dicentric chromosome breakage has been published! If you're interested in DNA damage, chromosome fragility, centromeres, and spindle forces you might find this interesting. I sure do! 😄 academic.oup.com/genetics/advan…
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