David Jacobson @Jacobson_Lab
Islet Electrophysiologist lab.vanderbilt.edu/jacobson-lab/ Vanderbilt University Joined February 2022-
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David Jacobson retweeted
Great new study that reveals a link between a TALK-1 K+ channel mutation (L114P) and maturity-onset diabetes of the young (MODY). Exciting potential for TALK-1 as a target in diabetes treatment! #DiabetesResearch #MODY #GlucoseHomeostasis biorxiv.org/content/10.110…
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Excited to share our study showing that a TALK-1 GOF mutation causes transient neonatal diabetes followed by a MODY-like phenotype. #TALK1 #Diabetes #Islet #KCNK16 #MODY #MonogenicDiabetes #NeonatalDiabetes #BetaCell #AlphaCell #Calcium #IonChannel #Dysglycemia #Insulin #Glucagon
Gi/o protein-coupled receptors inhibit beta-cell calcium entry through Na+/K+ ATPase activation. biorxiv.org/content/10.110…
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