Martin Jonikas @JonikasLab
@mjonikas.bsky.social I'm a scientist studying enhanced photosynthetic CO2 assimilation! Opinions are my own and do not reflect those of my employer. jonikaslab.princeton.edu Princeton, NJ Joined May 2015-
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Congratulations to Aastha Garde and Haoyu Wu! Grateful for support from @gatesfoundation, @FCDOGovUK, @NIH, @NSF, @hhmi_science, and @PrincetonMolBio.
Pyrenoid tubules are essential for supercharging CO₂ fixation, but they're hard to resolve by microscopy. So, we physically expanded cells to see where different proteins go (3 examples below). The central region appears specialized for CO₂ delivery! biorxiv.org/content/10.648…
Grateful to our funders @gatesfoundation, @FCDOGovUK, @NSF, @hhmi_science, and @PrincetonMolBio!
Congratulations to Sabrina Ergun, Claire Dignazio, Jonathan Bouvette, Haoyu Wu, Eric Franklin, and Claire McWhite!
The algal pyrenoid fixes ~1/3 of global carbon, relying on a unique membrane-within-condensate architecture. How is this architecture built? We discovered that the protein MITH1 draws membranes into the pyrenoid condensate by promoting wetting! 🌿💧biorxiv.org/content/10.648…
The US National Science Foundation (NSF) — a major funder of basic research — has restricted the flow of new research grants to a group of elite universities, Nature has learnt. go.nature.com/4uMeoxS
Now published @PNASNews! SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardtii pnas.org/doi/10.1073/pn…
We genetically disconnected starch from the matrix in the algal pyrenoid! A saga1;saga2 double mutant lacks a pyrenoid starch sheath! Our model: SAGA1 & SAGA2 locally initiate starch on the pyrenoid surface by enriching starch precursors. 🌞🦠🔬🔌👀 biorxiv.org/content/10.6..…
To all scientists immigrants: This is an amazing opportunity. The Vilcek family is super generous and has rewarded many immigrant scientists including Nobel Laureate @kkariko. Hope everyone eligible applies !
@hhmi_science's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, + salary & benefits. Postdocs can apply too. Opens 11/3! hhmi.org/programs/freem…
Congrats, Alex!! Well deserved!
Alexander Ploss, Princeton’s Harry C. Wiess Professor of Life Sciences and Molecular Biology, and the co-director of the Global Health Program, was awarded a 2026 Guggenheim Fellowship in the field of medicine and health. 🥂 princeton.edu/news/2026/04/2…
Congrats, @Shan_He_lab and Linnea Lemma!
Today in Nature Cell Biology, a collaborative effort across labs (Jonikas, Wingreen, Brangwynne) at Princeton discovers the key to regulating a biomolecular condensate. Congrats to first authors Shan He and Linnea Lemma! molbio.princeton.edu/news/2026/key1…
Now published @NatureCellBio! Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions nature.com/articles/s4155…
Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis biorxiv.org/content/10.110…
Congrats to Tori, Micah, Aastha, and @LianyongW! Grateful to @hhmi_science, @NIH, @NSF, @gatesfoundation, and @FCDOGovUK for supporting the work.
We genetically disconnected starch from the matrix in the algal pyrenoid! A saga1;saga2 double mutant lacks a pyrenoid starch sheath! Our model: SAGA1 & SAGA2 locally initiate starch on the pyrenoid surface by enriching starch precursors. 🌞🦠🔬🔌👀 biorxiv.org/content/10.6..…
We genetically disconnected starch from the matrix in the algal pyrenoid! A saga1;saga2 double mutant lacks a pyrenoid starch sheath! Our model: SAGA1 & SAGA2 locally initiate starch on the pyrenoid surface by enriching starch precursors. 🌞🦠🔬🔌👀 biorxiv.org/content/10.6..…
Nice examples of key discoveries that created industries and were only possible by funding basic exploratory research. nature.com/articles/d4158…
Now published @PlantPhys nph.onlinelibrary.wiley.com/doi/10.1111/np…
Excited to share our latest preprint! Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components biorxiv.org/content/10.110…
Congrats to the team including @Shanhe_PU, @lsquared64, @almcalvo, @lianyongw, @Ashwani_Rai1, @brangwynnelab, and Ned Wingreen! Grateful to @HHMINEWS , @NSF, @DOEScience, @NIH, and @HFSP for supporting this interdisciplinary project.
Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis biorxiv.org/content/10.110…
How did the US become the global leader in science and technology? Answer: decades of federal investment in basic research, including through the National Science Foundation and Department of Energy. aps.org/apsnews/2025/1…
Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis biorxiv.org/content/10.110…
Exciting new study from @aburlacot and @Yeh_Lab ! A genome-wide CRISPR screen in diatoms!
📣 📣 Wondering what allow diatoms to grow in the ever-changing environment 🌦️of the ocean🌊? Check out or latest work where we develop genome-wide CRISPR screen to unravel the genes🧬 critical for diatoms under dynamic light conditions☀️🌥️👇 Spoiler alert: it is
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