Waggoner Lab @LabWaggoner
Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social Cincinnati, OH Joined August 2018-
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Based on a new NOA recieved this month, we are looking for a postdoctoral fellow with solid foundation of molecular skills, creativity, and translational passion to help us develop innovative CARs for targeting discrete subsets of T cells. DM or email me if interested
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Reversible suppression of autophagy in a mouse model reveals neuronal resilience @ScienceMagazine science.org/doi/10.1126/sc…
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation science.org/doi/10.1126/sc… @ScienceMagazine @Stanford
3 papers @ScienceMagazine provide a clear picture of the features of opsins that lead to different spectral properties, activation and inactivation kinetics, and recycling 🇨🇳🇯🇵🇨🇭 science.org/doi/10.1126/sc… science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…
Cell-to-cell cooperation through membrane vesicles enhances antibiotic persistence @ScienceMagazine @ChristopheHer16 @BCMFromtheLabs science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…
The physiological state of neurons controls the expression of gene variants linked with psychiatric disease (preview by @panos_roussos) science.org/doi/10.1126/sc… science.org/doi/10.1126/sc… @ScienceMagazine @xinhe2 @UChicago
Medical students are using a popular research tool to pump out misleading studies Critics say TriNetX’s easy analyses of electronic medical records fuel quick-and-dirty publications from inexperienced authors @ScienceMagazine @joelving science.org/content/articl…
The enduring pursuit of science in America @ScienceMagazine @NeilShubin science.org/doi/10.1126/sc…
CD244 modulates bone marrow infiltrating CD8+ T cells and serves as a prognostic and immunotherapeutic target in acute myeloid leukemia sciencedirect.com/science/articl…
TGF-β and IL-2 differentially shape T follicular regulatory cell differentiation and stability in vitro nature.com/articles/s4142…
Waggoner Lab retweeted
RETRACTED! TL;DR: This study, which claimed the time of day had massive effects on immunotherapy efficacy, but which appeared fraudulent, now seems to certainly have been fraudulent. Many thanks to the editors at Nature for handling this quickly and correctly.
A lot of the key details of this study point towards the result not being real. I think we ought to regard it as fraudulent until proven real🧵 To start, the result is as strong as the observational results from the earlier literature. That's very unusual for a trial!
Waggoner Lab retweeted
Is science self-correcting? Not in this Elsevier journal. Two 'five-second-retractions' were never retracted, even though I reported them to the journal in 2015. Eleven years later.... nothing. My latest blog post: scienceintegritydigest.com/2026/06/24/is-…
Preprint: IRF8 restrains a neutrophil alarmin program that drives inflammatory remodeling of the bone marrow niche researchsquare.com/article/rs-994…
Hypoxia drives lactate accumulation in intratumoral NK cells histone lactylation at IGFBP2 promoter to enhance its expression, which inhibits MICA/B & Ecto-CRT on tumors to reduce sensitivity to NK cell killing cell.com/cell-reports/f… @CellReports 🇨🇳
Altered translation in early germinal center B cells triggers a vicious cycle of aberrant B–T cell interactions culminating in lymphomagenesis @JExpMed rupress.org/jem/article/22… commentary on rupress.org/jem/article/22…
Disparate off rates drive the agonism and antagonism of antibodies targeting the inhibitory FcγR in humans, hFcγRIIB @ImmunityCP @unisouthampton cell.com/immunity/fullt…
Waggoner Lab retweeted
Thats how it ended from last asco 2025. Expected end .
Waggoner Lab retweeted
Brought to you by (you guessed it) basic scientific research.
Daniel Cressy, 23, becomes the first person in Louisiana to be functionally cured of sickle cell disease through gene therapy
Waggoner Lab retweeted
Very desperate to see this work out. Especially after becoming a parent my opinions on the negative impact of even "just the cold" respiratory illnesses on quality of life, productivity & overall health have dramatically changed.
Latent cytomegalovirus disrupts innate NK cell responses to P. falciparum and impairs parasite control in first infection in adults @PLOSPathogens journals.plos.org/plospathogens/…
Adrian Liston @LabListon
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Journal of Experiment... @JExpMed
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Journal of Experiment... @JExpMed
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Ioannis Vlachos // @i... @ioavlachos
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Kali Meredith Pruss @KaliPruss
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Soumyabrata Guha @AceGuha
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Karen Taraszka Hastin... @KTHastingsMDPhD
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federica facciotti @federicafacciot
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Alison E Ringel @alisoneringel
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Meelad @meeladamouzgar
184 Followers 193 Following Computational Immunology PhD student in the @Bendall_Lab with @stanfordimmuno. @StanfordBioX Fellow. Community College educated. Handstand enthusiast.
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Landon Clark @landonmclark2
347 Followers 373 Following MD/PhD Candidate @VanderbiltMSTP | @Cambridge_Uni Churchill Scholar | germinal centers guy | Falcons and Braves fan | he/him ••
Sabrina Simoncelli @ssimoncelli
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