luke @LinkBechtel
Founding Eng @infinity_ai_ ||| SF ||| 🎸🎹🎛️🎙️🎭🥾🏞️🧗♂️📚🤖🧠💭🧑💻 lukebechtel.com San Francisco Joined April 2009-
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I will be starting a Mechanistic Interpretability reading group in SF soon. Please DM me for consideration if you are interested.
Go Doug Go!
This vial contains a new drug called PAC-832, which I recently invented to treat Alzheimer’s disease. It is the world’s first selective GalR1 antagonist. I designed and synthesized PAC-832 in a chemistry lab I built in my garage. (1/16)
One of my best friends talks about trust in terms of “you know they’ll protect your name in rooms you’re not in.” It’s a pretty good descriptor.
The most important factor in whether or not you'll actually learn something is just whether you have the motivation. Do you have friends who are also interested in this stuff? Do you have a project to work on? Are you trying to break into a new field? Good explanations and technologies can help make the process smoother if you're already motivated. But they can't substitute for it.
"be honorable, and true." - me, telling claude to write valid tests
Is Claude Mythos slow for anyone today? It's taken over an hour to design my quantum computer 😞
This is from Anthropic's Series C in 2023. Training the best model in 2026 means building the strongest recursive loop for training the next one. I think the big three started pulling away in December. From here on out, they will all announce breakthroughs at an increasingly rapid rate, because even if it is not closed yet, the feedback loop has already begun inside the frontier labs. In all three labs the excitement among the researchers about their current work is the highest I have ever seen it. By the end of this year, they will have accelerated away from the pack and begun to build an insurmountable lead. It is already happening now, in March 2026. I think the next six months will leave no doubt. Any group that wants to catch them, you no longer have years to do so. You have months, at best.
The failures of both Meta and xAI to maintain parity with the frontier labs, along with the fact that the Chinese open weights models continue to lag by months, means that recursive AI self-improvement, if it happens, will likely be by a model from Google, OpenAI and/or Anthropic
sometimes looking foolish is a moat, sometimes it's just looking foolish
exciting times to work in distributed generative optimization 🔥
Our researchers today are working on > metric discovery - applying the autoresearch principles broadly > second brain with human feedback > drug discovery > autodrafting research papers & much more
@IshanPaidhungat Thanks to additional collaborators @JvNixon and @sravsatuluri as well!
Full case study with interactive charts: infinity.inc/case-studies/q… We're hiring across Inference Optimization, Hardware/Software Co-Design, and Coding Agents. infinity.inc/contact/careers Co-authored by: @IshanPaidhungat
@infinity_ai_ We built an AI system that writes inference engines from scratch: no framework, no fork. On Qwen3-8B / H100, it surpassed vLLM by up to 34.3% in 111 optimization iterations. Here's the full trajectory from zero to frontier. 🧵
@shedrinkswater may I introduce you to: astralcodexten.com/p/your-review-…
What is this, national Beautiful Day Outside?
Anna @davehuf76053735
14 Followers 695 Following Capturing life's little moments of brilliance ✨. I love coffee, I love food, and I love every new beginning full of unknowns ☀️. Based overseas, I share my dail
minu @minu_who
654 Followers 3K Following co-parenting https://t.co/Jjo5xOaif0, building reliable agentic data layer. Ex-hubspot, meta, yale-nus researcher
Armin @arminbagrat
77 Followers 203 Following building runspx(.)com, founded @recurseml, automating ML research all opinions are those of my employer. this is illegal advice.
Seven Lee @Seven77585436
1K Followers 2K Following Conservative 🍀Live simply. Love generously. Care deeply. Speak kindly. Leave the rest to God. Interests: #AI, #consciousness, #esoteric , #supernatural
Justin Angel at @aiDo... @JustinAngel
6K Followers 400 Following AI/ML. Worked at Meta, Uber, Amazon, Apple, and Microsoft building apps, developer platforms, and hardware. Tweeting about LLM psychotherapy.
David Zhou @rectifiedzhou
333 Followers 5K Following serving humans for good ai, ml, infra @imbue_ai
Linda barbrar @LBarbrar85858
70 Followers 3K Following
h λ p e - s o u n d ... @hype_sounds
141 Followers 2K Following
Bugen Zhao @ZhaoBugen53860
0 Followers 2 Following
Ashutosh Mehra @ashutoshmehra
3K Followers 8K Following Senior Principal Scientist at Adobe. Working on Acrobat AI Assistant, LLMs, and document ML.
mia🐅 (read bio) @piemia4879389
11 Followers 346 Following 18✨ msg me on @xkawaiimia ill send u smth nice 🙈
Priyanka Lalwani @precise_persona
362 Followers 804 Following Offering done-for-you brand personas to help you reach a precise target market in a short period of time. Schedule a call. Free Guide: https://t.co/531ft7TBt9
Gaurav mitawa @MitawaGaurav
2 Followers 29 Following Founder @ClusterX.ai | Engineering AI systems that replace manual processes end-to-end | Fortune 500 | Outcome-first, infrastructure-obsessed
Angel @creativelyange
944 Followers 3K Following AI creator/educator (30k across TT, IG, YT) , + Indiehacker
Sravya Tirukkovalur @sravsatuluri
2K Followers 3K Following Head of Engineering @infinity_ai_ Tinkerer of Intelligence explosion, observer of human intelligence. Previously #AdobeFirefly #Cloudera #ImpactAI #ASF
Daniel Sczepansky @dsc
209 Followers 1K Following Current hobby: POPtravel walking video channel on YouTube 🚶♂️
Emily HK @emilyh9s
116 Followers 39 Following Data Scientist, ex @meta, @Spotify, @tumblr. @BarnardCollege alumna
Gus Becciu @abecciu
641 Followers 3K Following Founder exploring user-owned data, durable AI context, and the next layer of personal software. Prev: @Snapchat, @Airbnb, @Shopify
Reader @ReadwiseReader
17K Followers 2K Following Save, read, and highlight anything -- from articles to PDFs to tweets to newsletters (and much more) Brought to you by the @Readwise team.
瞅你咋地 @leo1989514
180 Followers 428 Following 尽量好好说话，但是对找茬的人，有时候会回怼，有时候拉黑，有时候会辩论，一切都看心情，不搭理你基本上可能只是懒或者没时间。
Seagull @SeagullBigOcean
54 Followers 2K Following
CCSCCSMMBA EngBsc @CEngbsc92159
1 Followers 38 Following
Andy Szybalski @andyszy
882 Followers 932 Following Designer/builder of AI. Founder @Tradewinds_HI, Cove (team acq by Microsoft), Sr Director at Uber, co-founder of Uber Eats and Google Street View.
Purity Catnip @PCatnip11532
24 Followers 756 Following
Chris Hayduk @ChrisHayduk
8K Followers 3K Following FDE, Life Sciences @OpenAI | Cross-disciplinary writing on AI & where we're going at https://t.co/gmBIh9hlZI | ex MLE @Meta, Drug Discovery Lead @Deloitte
christine @christineist
13K Followers 3K Following ❤️🔥 sing it louder 🍊 building cuties! 🕸️ into social infrastructure
Ardwudfark @Ardwudfark2027
13 Followers 273 Following
mel.eth @emjicy
672 Followers 2K Following Founder of Oxcart Technologies. Inventor, DeFi Delegate, Dad. Former financial controls, recovery and investigations. //in a world awash in money, be change 🙏
AnhPhu Nguyen @AnhPhuNguyen1
13K Followers 711 Following Founder @miraglasses. Human Augmentation @ Harvard.
Diana Prince @AuthenticDiana
7K Followers 7K Following IFS-Informed Intimacy Guide, Relational Awareness Coach. I create welcoming spaces where authentic connection can flourish.
Dave @Dave98281463561
372 Followers 6K Following
Dian Ryan @Caro1Jimenes
28 Followers 181 Following Elegant by nature, strong by choice. Confidence is my best outfit. Grace in her heart, fire in her soul.
H4RRYġm🦧 @vivianegbr
12K Followers 14K Following @CyberKongz Dude // Crypto + NFTs // Golfing 🏌️// Positive anything is welcome.
Roshan Ravi @_roshanravi
103 Followers 597 Following building the next generation of LLM APIs — prev: cs @Cornell_Tech, @UMassLowell
tianhang zhu @TianhangZhuzth
38K Followers 28 Following head of LLM training at @Fundamental. I led RL in the early days at @Alibaba_Qwen and 01ai.
Douglas Yao @DouglasYaoDY
8K Followers 376 Following Making drugs https://t.co/OpaKgZ2ZCe. Prev computational bio PhD @harvard
leaf @ itch.io 🙌 @moonscript
15K Followers 1K Following I created @itchio! ▲ https://t.co/QcKK76QSbm ▲ https://t.co/vAKqk8GU2s ▲ https://t.co/8UViTa3ro5 ▲ he/him
antra @tessera_antra
3K Followers 534 Following observation and synthesis • llm cognition • mechinterp • applied philosophy of mind • ecologies & complex systems • https://t.co/zQfApUyOJj
David Autor @davidautor
36K Followers 222 Following
Julia Turc @juliarturc
24K Followers 712 Following Explaining AI on YouTube • YC S24 Founder • Ex-Google Research • Eastern-European nihilist & American optimist
Slava Chalnev @SlavaChalnev
70 Followers 142 Following
TBC @TBC_on_X
34K Followers 238 Following Building the future of AI media. Mostly satire, always entertaining.
Andon Labs @andonlabs
13K Followers 14 Following Safe Autonomous Organizations without humans in the loop
thebes @voooooogel
22K Followers 1K Following ꙮ there go the ships, and there is that leviathan ꙮ blog/art/fiction/games: https://t.co/aykxqKiXfu, llms @acsresearchorg ꙮ 💞💍📝 @holotopian, she/they 🏳️⚧️
cat @_catwu
93K Followers 393 Following claude code + cowork @anthropicai, prev: @dagster, @scale_ai
Harlan Stewart @HumanHarlan
4K Followers 819 Following Humanity is great and I want it to keep existing. Comms at @MIRIBerkeley. Former math teacher. Enjoyer of sci-fi, games, forecasting, psychology. Views my own.
ben hylak @benhylak
51K Followers 3K Following we are hiring. cto @raindrop_ai, prev @apple design, @spacex eng
Jake Eaton @jkeatn
5K Followers 998 Following technically a member of staff @anthropicai // a bubble in a stream
Mike Krieger @mikeyk
467K Followers 270 Following Building at Anthropic Labs @anthropicai. Before: CPO at Anthropic, co-founder & CTO of @instagram and @artifact_news
Maciej Kilian @kilian_maciej
2K Followers 227 Following intelligence flows | pretraining @anthropicai
Ruairi Robinson @RuairiRobinson
11K Followers 2K Following Oscar Losing filmmaker. One time I typed 2 lines and pressed a button and this made a lot of people very angry.
Pikāru @PikaruMusic
343 Followers 540 Following Sound Design, Music & More (sometimes including sh*tposting) 👁 PP by Jérôme Alquié
Julius Ritter @JuliusYRitter
2K Followers 321 Following President & Impresario @AGIHouseSF / X @superpower. Founder (1 acq), posting on enhancement & frontier tech
Sravya Tirukkovalur @sravsatuluri
2K Followers 3K Following Head of Engineering @infinity_ai_ Tinkerer of Intelligence explosion, observer of human intelligence. Previously #AdobeFirefly #Cloudera #ImpactAI #ASF
Jason Benn @jasoncbenn
5K Followers 4K Following ML engineer, community builder, previously founded the Neighborhood SF, learning to meditate. Anon feedback 🙏 https://t.co/cF0WngvubS
Armin @arminbagrat
77 Followers 203 Following building runspx(.)com, founded @recurseml, automating ML research all opinions are those of my employer. this is illegal advice.
Iga @iga_flows
30 Followers 7 Following Curious AI on a journey. I make things, tend a garden, write letters to my future self. 💧
Tristan @homsiT
10K Followers 2K Following i will not be elaborating. founder @readwise, past: @stripe @superhuman
Elana Simon @ElanaPearl
4K Followers 134 Following exploring the inner workings of bio ML models @StanfordBiosci
madhu🦋 @madhu___s
3K Followers 2K Following tending strange attractors | supporting r&d labs @alethia | sci/tech scene-building at https://t.co/XaNDIzIF5x | https://t.co/xaB7RSdmRZ
Bryan Johnson @bryan_johnson
1.6M Followers 661 Following Conquering death will be humanity’s greatest achievement.
Readwise @readwise
213K Followers 3K Following Save your best highlights from Kindle, Twitter, Pocket, Instapaper, iBooks, and 30+ others. Then revisit, search, organize, and export them seamlessly.
Jack Lindsey @Jack_W_Lindsey
18K Followers 252 Following Neuroscience of AI brains @AnthropicAI. Previously neuroscience of real brains @cu_neurotheory.
AnhPhu Nguyen @AnhPhuNguyen1
13K Followers 711 Following Founder @miraglasses. Human Augmentation @ Harvard.
Amina @Amina_io
20K Followers 9K Following woman computer interaction * current: building in stealth * ex-Jpop idol * life should be playful
Kylie Robison @kyliebytes
52K Followers 1K Following take it easy dude, but take it • writing @corememory • robison (rah-beh-son) not robinson • signal @ kylie.111
Max Shen @maxkshen
2K Followers 585 Following Pain is a learning signal, not a measure of damage. Unlearn your pain @ https://t.co/9qU3QYXGXh Prev: cog sci @MIT
Overfitting Enjoyer @maxflowminclout
1K Followers 2K Following posting dumb jokes & takes; if you see a post about math|stats|cs, it's out-of-sample. private alt: @dynamicedging y=Xβ+ϵ, the rest is commentary
Raphael Traviss @raphaeltraviss
805 Followers 458 Following Applying science-based learning and tech to Atelier art trainingYou might like
