MinneBIO @MinneBio

Empowering Biotech Excellence 🌱 | Leading Supplier of Bio-reagents | Your partner in protein preparation🏆 | Let's innovate together! 💡 #BiotechInnovation minnebio.com Saint Pau, Minnesota 55114 Joined August 2023

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李老师不是你老师 @whyyoutouzhele

4 months ago

台州街头“安全教育”：没戴头盔，先挨两巴掌网友投稿：3月2日，浙江省台州市黄岩区诚新广场，一名群众因骑电动车未佩戴头盔被交警拦下检查。在执法过程中，当事人进行陈述申辩时，被交警狂扇耳光。

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MinneBIO @MinneBio

6 months ago

Thank you & Happy Holidays from MinneBio!

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MinneBIO @MinneBio

6 months ago

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MinneBIO @MinneBio

6 months ago

@Mishi_2210 116

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MinneBIO @MinneBio

7 months ago

@Matt_Pinner 17

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Eric Topol @EricTopol

7 months ago

Engineering T cells (CAR T) for treatment of solid cancers has had mixed success to date. Two reports today raise the promise of using interleukin-9 as a way to raise efficacy @ImmunityCP cell.com/immunity/fullt… cell.com/immunity/fullt…

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MinneBIO @MinneBio

7 months ago

@Brandon_Beaber Great achievement in developing the antivirus vaccine!

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MinneBIO @MinneBio

7 months ago

@QianXuyu @ChildrensPhila @PennMedicine Congrats！

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Silvi Rouskin @silvirouskin

8 months ago

As I’ve said multiple times , postdoc is the worst job you can have with a PhD in these times. I try hard to soften this blow for anyone in my lab and it barely scratches the surface..

Andrew Akbashev @Andrew_Akbashev

8 months ago

Postdoc time is often harder than PhD. You have little time. Competition is higher. And you MUST stand out. + Your contract may end any moment. + Your salary is often low (for your age/education). + You’ve just relocated and prepare to relocate again. No wonder that Max

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William A. Wallace, Ph.D. @WilliamWallace

8 months ago

Your immune system doesn't only defend, it remembers This diagram maps how the body’s innate and adaptive immune systems work together to identify, attack, and remember pathogens. It shows how different immune cells, antibodies, and signaling molecules coordinate to protect against infection while maintaining balance. 1️⃣ Innate immunity: the immediate response The innate system acts within minutes, providing broad defense through physical, chemical, and cellular barriers. 🟢 Example: Skin, mucus, and stomach acid block pathogens, while macrophages, neutrophils, and natural killer cells identify and destroy invaders using pattern-recognition receptors. 🟢 Example: The complement cascade amplifies inflammation and flags pathogens for destruction by immune cells. 2️⃣ Adaptive immunity: the targeted response The adaptive system learns to recognize specific antigens and produces lasting protection through specialized B and T cells. 🟢 Example: B cells release antibodies (IgM, IgG, IgA, IgE, IgD) that neutralize toxins and tag microbes for clearance. 🟢 Example: T cells coordinate and execute defense—helper T cells activate macrophages and B cells, while cytotoxic T cells trigger apoptosis in infected cells. 3️⃣ Antibody specialization and immune memory Each antibody class has a unique role in defense and long-term immunity. 🟢 Example: IgM is the first antibody made in infection, IgG provides long-term protection and crosses the placenta, IgA guards mucosal surfaces, and IgE mediates allergic reactions. 🟢 Example: Memory B and T cells remain after infection or vaccination, allowing faster and stronger immune responses upon re-exposure. 4️⃣ Active and passive protection Immunity can be acquired through natural infection, vaccination, or temporary antibody transfer. 🟢 Example: maternal antibodies passed through breast milk provide short-term passive defense. The immune system’s strength lies in its coordination—an instant, non-specific response that buys time for a targeted, adaptive defense that remembers what it has seen.

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Derya Unutmaz, MD @DeryaTR_

8 months ago

Is it okay if I call this article bullshit?! They didn’t ask me about this; I’m a scientist too, you know😅 I love it here on X, but I find Bluesky boring & depressing. Also, I dislike it when they strongly imply that all scientists must share the same ideology or think/act same!

Andrew Akbashev @Andrew_Akbashev

8 months ago

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MinneBIO @MinneBio

8 months ago

@yisongyue @klbouman @Caltech Congrats!

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MinneBIO @MinneBio

8 months ago

The Extracellular Matrix is a complex protein network that supports cells, regulates signaling and migration, and, together with neighboring cells and factors, shapes the microenvironment, influencing behavior in cancer, fibrosis, and tissue remodeling. minnebio.com/blog/ecm-cell-…

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MinneBIO @MinneBio

8 months ago

A seminar on ECM Proteomics Research by Prof Alexandra Naba from U Illinois Chicago. We greatly appreciated the insightful presentation & also thank Prof Ying Ge from U Wisconsin - Madison for organizing the seminar. minnebio.com/blog/extracell…

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MinneBIO @MinneBio

8 months ago

@CFI_UMN @briantfife @fifelab Congratulations!

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MinneBIO @MinneBio

8 months ago

CD8⁺ T cells remain overactive and exhausted long after COVID-19 infection, keeping the immune system in a chronic inflammatory state. This persistent immune dysregulation could drive Long COVID symptoms by sustaining low-grade inflammation and disrupting normal immune balance.

Jon Douglas @atranscendedman

8 months ago

Researchers analyzed 73,000 immune cells from COVID-19 patients. They found that memory CD8+ T cells stay overactive and exhausted long after infection, keeping the immune system in a low-grade inflammatory state that may drive Long COVID. frontiersin.org/journals/immun…

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MinneBIO @MinneBio

8 months ago

COVID-19’s fight isn’t over; Long COVID is real and growing. Calling it an “Airborne AIDS” reflects scientific concern, highlighting the struggle to stay transparent without spreading fear—and exposing society’s deep divides over chronic illness.

David It Up! @Dave_it_up

8 months ago

Eight Billion COVID Infections a Year: What the “Airborne AIDS” Debate Reveals About Long COVID Advocacy (Based on : AJPM Focus study “COVID-19 is ‘Airborne AIDS’: provocative oversimplification, emerging science, or something in between?”) A strange thing is happening in

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MinneBIO @MinneBio

8 months ago

It’s a good start. Rational design could yield improved material properties, bringing us closer to the realization of a true “Egg Computer.”

LaurieWired @lauriewired

8 months ago

Every year, we get closer and closer to a true “Egg Computer”. We’ve already made: - Egg Transistors - Egg Resistive Memories - Egg Supercapacitor electrodes Albumin is a hilariously good organic semiconductor material.

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MinneBIO @MinneBio

8 months ago

Structure is only part of the story— ~30% IDRs. PeptoneBench & PepTron tackle this complexity: PeptoneBench connects machine learning & experiment to assess ensemble realism, while PepTron, trained on synthetic IDRs, matches BioEmu on DR & performs strongly on folded proteins.

Kyle Tretina, Ph.D. @AllThingsApx

8 months ago

Structure is not even half of a protein's story; ~30 % of proteins are disordered. 🧬 PeptoneBench bridges ML and experiment (CS/SAXS/RDC/PRE) to test ensemble realism. 🧬 PepTron learns from synthetic IDR ensembles, matching BioEmu on disorder while staying strong on folded