Andrew Balmer @Quackscience
Senior Data Scientist @sangerinstitute | Antimicrobial resistance evolution | Researcher and coffee drinker andrewbalmer.mystrikingly.com Cambridge, UK Joined June 2013-
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Most AMR data is still collapsed to “resistant vs susceptible.” But resistance often shows gradual shifts before cut-offs. AMR Cartography maps full profiles in 2D — revealing co-resistance, sub-breakpoint changes & lineage patterns. 🔗 biorxiv.org/content/10.110…
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🚨 New paper in eLife! We analysed >100k malaria parasite samples to track the rise of artemisinin resistance. Resistance is now emerging in Africa, echoing SE Asia 10–15 yrs ago. Genomic surveillance is key to staying one step ahead! elifesciences.org/articles/10554…
The framework works across species & drug classes — and the code is open-source. Would love feedback from anyone working in AMR surveillance! Preprint: biorxiv.org/content/10.110…
Applied to 3,600+ pneumococcal isolates, AMR Cartography revealed lineage-specific resistance and the genetic changes driving multidrug resistance.
New Preprint! 🚨: Most AMR data gets collapsed into “resistant” vs “susceptible.” But resistance isn’t a simple switch — it changes gradually, and often in correlated ways across drugs.
Andrew Balmer retweeted
[New pre-print🚨] When a single genotype (pbp) confer resistance to multiple antibiotics (penicillin and cephalosporins), how do we make sense of genetic changes and their impact on AMR? A new concept - AMR cartography is invented by @Quackscience biorxiv.org/content/10.110…
We’ve just posted AMR Cartography on bioRxiv: a way to study multivariate drug resistance and connect it to genotypes. Would love feedback from people working with surveillance MIC data! @AntibioticResis @crypticproject biorxiv.org/content/10.110…
Just posted our new preprint: Antimicrobial Resistance Cartography – A generalisable framework for studying multivariate drug resistance @CamInfectDis @CambridgeDDU biorxiv.org/content/10.110…
AMR Cartography lets us visualise how different pneumococcal lineages have distinct multivariate resistance phenotypes. @pneumowatch
New preprint: Antimicrobial Resistance Cartography — a simple way to map multivariate drug-resistance phenotypes, using data from @CDCgov. biorxiv.org/content/10.110…
Andrew Balmer retweeted
Antimicrobial Resistance Cartography: A Generalisable Framework for Studying Multivariate Drug Resistance biorxiv.org/content/10.110… #biorxiv_genomic
Andrew Balmer retweeted
Introducing AMR cartography - brilliant work by @Quackscience
Antimicrobial Resistance Cartography: A Generalisable Framework for Studying Multivariate Drug Resistance biorxiv.org/content/10.110… #biorxiv_genomic
Andrew Balmer retweeted
Announcing the latest version of MalariaGEN’s world-leading malaria parasite data resource: Pf8! 📢 In this release, you’ll find: 🦠 33,325 parasite whole genomes 🌍 Samples from 122 different locations 🗓️ 56 years of data Read more: malariagen.net/article/pf8-re…
Andrew Balmer retweeted
Our next Journal Club will be all about the new Pf8 data release! Join Dr Nina White, Senior Data Scientist at the Genomic Surveillance Unit (@sangerinstitute) to learn to make the most of this unique malaria parasite data resource. 📅July 22, 1:30pm sanger.zoom.us/webinar/regist…
Andrew Balmer retweeted
morning coffee and @Quackscience Global Spread of Artemisinin Resistance: Insights from over 100K P falciparum Samples Thx @MESAmalaria @ChatWithChauke @ninawaleEEB @eselimnl @cl32_sanger @RichardDPearson @ingeneswetrust @cristina_ariani youtube.com/watch?v=s0by0c…
Andrew Balmer retweeted
Egypt declared malaria-free after 100-year effort, BBC reports. bbc.com/news/articles/…
Andrew Balmer retweeted
Our October Journal Club is all about drug-resistant #malaria parasites💊 Dr Andrew Balmer will delve into a recent review that maps data from 112,000+ P. falciparum genome sequences worldwide to track kelch13 mutations: biorxiv.org/content/10.110… Register: sanger.zoom.us/webinar/regist…
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