Pukkila-Worley Lab is also @rpwlab.bsky.social @RPWLab
Research Scientist. Infectious Diseases Physician. Professor. MD-PhD Program Director. Innate immunity, intestinal epithelial cells and worms. UMass Chan. umassmed.edu/pukkila-worley… Worcester, MA Joined May 2017-
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Congratulations to this 🌟!! @UMassChan @UMassMDPhD student @tse_elegans has achieved every measure of success possible during her MD and PhD training, culminating the the Dean's Award for best PhD thesis. Congrats Sammy. I couldn't be more proud. #UMassChan2026
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#PhDone! Congrats to @UMassChan @UMassMDPhD student Akshay Alaghatta on his successful defense today! PhD #6 for the @RPWLab
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Check it out!! Stellar matches for our MSTP students!! Congrats to our double docs on this milestone in their professional careers as physician-scientists! These sites are so lucky to have you. We are immensely proud! #Match2026 #MDPhD #UMassChanMatch
@BostonChildrens @MayoClinic x 2 @bcmhouston @BrighamWomens @MaineMed ! Incredible @UMassMDPhD graduates are heading your way!!
Beaming with pride this afternoon for @tse_elegans, a star MD-PhD student from my lab, and 5 other @UMassChan @UMassMDPhD students after INCREDIBLE Match Day Success! Sammy heading to the Pediatric Residency at Boston Children's Hospital!
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
New publication alert! Five MD/PhD students on the same paper? Now that's what we call collaboration! Congrats to our students, alum, and co-director Dr. Mark Johnson on their new publication!
2025 RPW Lab Outing! This year, a hike up Mt. Watatic on a blue bird day. Love our lab!!! :-)
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Read Pukkila-Worley, MD, is the new director of the MD/PhD program: direc.to/n8PN Dr. Pukkila-Worley has mentored dozens of MD/PhD graduate students since joining @UMassChan in 2014. The @RPWLab studies host-pathogen interactions and bacterial pathogenesis. @UMassMDPhD
Check out the cover of @TrendsImmuno !! Art by lab alumna @tse_elegans to highlight our lab's review in the issue by Khursheed Wani on enzymatic TIR proteins in innate immunity!!! cell.com/trends/immunol…
Incredibly proud of @Mo_AliNasrallah , a @UMassChan @UMassMDPhD graduate from my lab. So much fun to celebrate his accomplishments and those of his classmates this weekend. #UMassChan2025
Excited to share another review from the lab, out this week in @TrendsImmuno . Join us for a fun tour of what we think are the coolest proteins in all of innate immunity! cell.com/trends/immunol…
Excited to share our recent review out in @NatRevImmunol . We discuss mechanisms that identify patterns of pathogenesis -- specific ligands or symptoms in the host that indicate active infection with an infectious microorganism. @UMassChan
Patterns of pathogenesis in innate immunity: insights from C. elegans bit.ly/3YFbXzi
Back-to-back @UMassChan Dept of Medicine Halloween Party Costume Award Winners!!!
Absolutely bursting with C. elegans, @UMassChan , @MGHMolBio , Simches 7 pride this morning!!! Congrats Victor and Gary!!!!
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Looking for an up to date review on dna sensors and their role in autoinflammatory diseases check out this review from @Mingqi7up 👇
nature.com/articles/s4159… I hope this is a helpful review! Appreciate the opportunity to co-write this review in @NatImmunol with my mentor @FitzgeraldKate. Thanks to all the reviewers' comments which significantly elevated our work and thanks to the unsung artists for their art!
Welcome Karthik!!!
We are super excited to be welcoming @karthik_varanas to the Division of INnate Immunity @UMassChan this November to start his lab @UMassChanPII ---welcome to @UMassChan @UMassChanGSBS #newPI
Sharing a nice write-up from @UMassChan highlighting @tse_elegans and her recent companion papers from my lab that were published last week in @ImmunityCP and @CellReports . umassmed.edu/news/news-arch…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Online now: Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles dlvr.it/TDP14w
SARM - an enzymatic TIR protein. Perhaps the most ancient immune regulator in the Tree of Life and the origins of innate immunity itself. But, is it an immune sensor in animals?
UMass Chan Medical Sc... @UMassChan
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Vanni Bucci, Ph.D. �... @BucciVanni
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UMass Chan MD/PhD Pro... @UMassMDPhD
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