Safavi Lab @SafaviLab
Exploring and developing applications of biomedical peptides from marine venoms | Tweets by lab members. #conesnails #venom 🇩🇪🇵🇭🇩🇰🇭🇰🇺🇸🇫🇷🇦🇺 helenasafavi.com Salt Lake City, Utah, USA Joined January 2021-
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Another news piece on why cone snail venom is an untapped source of drug discovery. Thanks for covering our studies!
A deadly sea snail has evolved a unique method of hunting that uses insulin-like compounds as a biological weapon. Research reveals that the geography cone snail releases a mix of mimic molecules into the water, altering its prey’s #metabolism and inducing a state of stupor. This
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A very nice piece covering our story on the unusual glucose-lowering hunting strategy used cunningly by the fish-hunting cone snail, Conus geographus. Check it out!
Cone snails in the tropical waters of Palau have a secret weapon. Researchers (@UUtah) found that one cone snail deploys insulin- and somatostatin-mimicking toxins that crash fish blood glucose levels. bit.ly/3CrY5A9
A great cover story in @nytimes magazine showcasing how venomous animals provide ingenious solutions to solve some of the long-standing problems in drug development. It was great showing Kim our cone snail aquarium, and our exciting research. nytimes.com/2024/11/13/mag…
Another example of why cone snails are rich drug source! Another great collaboration with the Toto Olivera lab at @UUtah
Cone snails produce χ-conotoxin to hunt other snails. These toxins are potential anti-pain drugs. Funtastic work from Sam Espino and collaborators of the Olivera Lab! academic.oup.com/mbe/article/do… #ConeSnails #conotoxin #venom
Safavi Lab retweeted
"What do online grocery shopping, venomous snails, and foot biomechanics have in common?" Find out! Largest-Ever @UofUDMRC @UofUHealth Retreat Tackles Problems from Public Health to Drug Development uofuhealth.utah.edu/newsroom/news/…
Don’t miss out on this seminar featuring our very own Dr Thomas Koch!
Join us on 9 October at 5pm CET for a new EUVEN seminar featuring Thomas Koch discussing cone snail venom evolution, and Schyler Ellsworh discussing mechanisms of venom resistance in flies. Register at bit.ly/3EUvDVe @Schy_Ellsworth @LundKoch
Great opportunity to work in a great lab with a great mentor!
Interested in #pain #pharmacology and structural biology and looking for a master's thesis project in Copenhagen? Read here to see more and apply for an intriguing project: ucph.jobteaser.com/da/job-offers/…
Helena gave a stellar tenure talk today, drawing different examples of prey-hormone mimicking, doppelgänger toxins found in cone snail venoms!
Safavi Lab retweeted
On Thurs Sept 12, Helena Safavi @SafaviLab will give her tenure talk entitled "Insights from the Biology, Behavior, and Evolution of Venomous Animals for Drug Discovery." 12pm at HSEB Alumni Hall!
Many thanks also to @EivindUndheim and @PoulNissen for being amazing PhD assessors!
Proud to present our newly minted Dr Sophie PhD of the Safavi lab! 🐚🎓🎈🎉🎊 very well deserved for all her hard work! Also nice to see past members of the Safavi lab in Copenhagen!
What a great time at Yellowstone 🌋with @StingScience, @waldensciencing, @LundKoch, @yeung_hyw, @irisbeara and other amazing people (Lars, Celeste, Vanessa) from 🇩🇰🇦🇺who are not on the X universe. Looking forward to your next visit in Salt Lake City!
@LairmoreDVMDean @OneHealthUCD @onehealth_csu There are surely yet more nature's secrets to be unveiled. Thank you for your interest in our work!
@SimoneCappelli6 Very much agree! Thank you for mentioning our work!
@ChrisStringer65 Thank you so much for noticing our work!
@dr_muniyappa thank you so much for your interest in our work!
Safavi Lab retweeted
Be sure to check out the full article by @SafaviLab @LundKoch @UofUBiochem: Prey Shifts Drive Venom Evolution in Cone Snails buff.ly/4dw4t6C
@DanielJDrucker @NatureComms thank you for mentioning our work!
🧵5/5 Special thanks to @janetiwasa for creating this wonderful animation!
🧵4/5 This work is led by @yeung_hyw, @irisbeara, @LundKoch and @waldensciencing from our lab. Also amazing collaborations from groups at UCPH @UCPH_health 🇩🇰@Alphacell_metab, @H_Brauner, @kattesch, Jens Juul Holst and Toto Olivera's lab at the U of Utah 🇺🇸 @UUtah @UofUBiochem!
Excited to share our latest story on how fish-hunting cone snail uses a combination of weaponized insulin and somatostatin-like toxins to disrupt glucose level in its fish prey 🐚⚡️🐠🍬 Check out our paper and animation to learn more: nature.com/articles/s4146… @NatureComms 🧵1/5
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