Sebastian Scheer @SebScheer
„Back off man, I’m a scientist.“ Epigenetic control of NK cell function @LIH_Luxembourg Esch-Sur-Alzette, Luxembourg Joined January 2012-
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@Dr_HeFeng @LIH_Luxembourg @FnrLux @lcsb_uni_lu Congrats! Well done!
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@HSudholz @Dr_Nick_Bikes What a pleasure it was! Congrats and well done!
Sebastian Scheer retweeted
NK cells are an important anti-cancer defense, but what happens if they turn into a different cell type? A new study from @SebScheer @Dr_Nick_Bikes identified a gene without which NK cells turn into a weaker cell type, making them worse at fighting cancer. bit.ly/3SKxSCl
Sebastian Scheer retweeted
Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." nature.com/articles/s4159…. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED
Sebastian Scheer retweeted
Thrilled to announce the publication of our latest research in Nature Immunology. Joining forces with 20 laboratories in Europe and USA, we identified the three prominent NK cell subsets in human: NK1, NK2, and NK3: rdcu.be/dMuAs
Sebastian Scheer retweeted
Junior Research Group Leader position: Join the Würzburg Infection and Immunology community! nature.com/naturecareers/…
In our review article, we now assess the current literature and highlight challenges and possibilities around the "conductor" DOT1L and its immunomodulatory functions, that may pave the way for innovative therapeutic approaches. bit.ly/3z9jYmg
...followed by @liamkealy and @KimLJacobson discovery of DOT1L's importance in B cells. bit.ly/3xrMrDl
After our discovery of DOT1L's role in NK cells bit.ly/3XsfSQc @CellReports, we now published the cherry on top of 7 years of research on DOT1L in the immune system @MonashBDI and @LIH_Luxembourg! @JessicaRunting @DrDThiele @liamckealy bit.ly/3z9jYmg @FnrLux
Sebastian Scheer retweeted
New publication from our lab 📣 cell.com/cell-reports/f… We demonstrate that Histone methyltransferase, DOT1L, limits NK cell conversion to ILC1s, a subset that can be observed in tumors in response to TGF-β and is correlated with poor tumor control @HSudholz @SebScheer
Sebastian Scheer retweeted
🖐A new #job opening for a 2-y position as a postdoc in my team! 🔺I'm considering only applications which include responses to the 3 questions I asked in the ad ;) So, read it before applying. 🙏 Help me circulate that job offer :) lih.lu/fr/job-fr/?val… @LIH_Luxembourg
Back home after a wonderful meeting of Functional Epigenomics in Saarbrücken. Going back to @LIH_Luxembourg with many new inspirations and the excitement that understanding and exploiting epigenetic mechanisms in immune cells will be key to solve many problems in the clinic.
@colbyzaph Big congrats to these exceptional students! However, also a big „well done“ to the PhD „dad“.
Sebastian Scheer retweeted
Huntington and colleagues describe the functions of Ikaros and Aiolos in NK cell development. Read it here: rdcu.be/dvLeC nature.com/articles/s4159…
What Harry says. Well done, team!
Excited to have our paper out in @NatImmunol IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development nature.com/articles/s4159…
Sebastian Scheer retweeted
I am hiring, please RT🙏🙏 POSTDOC: a molecular biologist to study the mechanism of chromatin modifiers in gene repression. careers.adelaide.edu.au/cw/en/job/5127… RA & LAB MANAGER: a protein biochemist & to lead the laboratory operations within a brand-new lab. careers.adelaide.edu.au/cw/en/job/5128…
Welcome to the @IEE_Research_Gp team, May Wantz! May will work on the epigenetic regulation of NK cell function as part of our @FnrLux and @FondationCancer funded EPICON project @LIH_Luxembourg. May you do well! 😉
Sebastian Scheer retweeted
A @MonashBDI study has found that a protective immune feature may be lacking in people with chronic infections caused by parasitic worms, which can help lead to improved #treatments and human vaccines. @MonashCCS #globalhealth Read it on @MucosalImmunol: pubmed.ncbi.nlm.nih.gov/37392971/#full…
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