Team Fox @TeamFoxDetroit

Everyone has a reason for showing up. In this video, you'll hear why our Team FOX members are attending the 10th anniversary Team FOX Detroit Gala and what this incredible evening means to them. Now we want to know... who are YOU coming for? • Join us for an unforgettable night of hope, impact, and community. Every ticket helps make a difference. Get your tickets today before they're gone! Link in bio. share.google FTfitygfu7sYOSzlv#teamfoxdetroit #parkinsonsawareness #teamfoxmjff #parkinsonsresearch

Parkinson’s is part of my story, but purpose, hope & community write the next chapter. We raise funds for MJFF because research gives hope—and hope keeps us believing in what’s possible. #michaeljfoxfoundation #teamfoxmjff #teamfoxdetroit

Join us for the Team Fox Detroit Gala as we celebrate 10 years of impact in support of The Michael J. Fox Foundation. Together, we are raising critical funds for Parkinson’s research and honoring the power of community, hope, and action. We would love to see you there!

“When we imagine a future of disability and decline, we're taking steps to prepare for that—rather than taking steps to live fully today." 👉 Watch the full episode here: buff.ly/v3FhbI8

Focused ultrasound and pallidotomy: what can lesions teach us that DBS cannot? A lesion means creating a permanent interruption in a brain circuit. Deep brain stimulation (DBS) uses electricity to modulate and reshape abnormal circuits without destroying tissue and importantly it can be adjusted, optimized and reversed if needed. Adam Zaidel and colleagues described in a fascinating paper (2008) in the European Journal of Neuroscience how prior pallidotomy lesions altered the physiology of the subthalamic nucleus (STN) years later in folks living w/ Parkinson's disease. As focused ultrasound lesioning rapidly expands across the globe, this older work may provide important clues into how lesion therapies and DBS differ in their effects on brain circuits. Thanks to my friend Hagai for reminding me about this one. Key points: - Prior pallidotomy reduced abnormal activity and oscillations in the STN, suggesting that lesioning one node in a network can reshape activity in distant connected regions. - The effects were durable and measurable years later, supporting the idea that lesion therapies may permanently reset portions of dysfunctional brain circuitry. - Despite these changes, STN DBS remained effective in many individuals, highlighting that lesioning and stimulation may improve symptoms through overlapping but distinct mechanisms. My take: The recent enthusiasm surrounding focused ultrasound is exciting and appropriate. For carefully selected folks, lesion therapies can be transformative. However, focused ultrasound and DBS are fundamentally different interventions and should not be viewed as interchangeable. DBS is more like installing a dimmer switch in a room. You can turn it up, turn it down, move the settings around and adapt as the disease evolves. Focused ultrasound is more like removing a wire from the circuit entirely. Sometimes that may be exactly the right strategy, however, once the wire is cut there is no putting it back. Here are 5 points that resonated w/ me: 1- Lesions teach us important aspects of neuroscience because they reveal what happens when a node in a brain network is permanently removed. 2- DBS teaches us something different because it allows us to observe and manipulate brain networks in real time. 3- Parkinson's disease and tremor are network disorders and not simply diseases of one structure or one target. 4- The reversibility and programmability of DBS remain major advantages, especially for younger folks and for diseases that evolve over decades. 5- Focused ultrasound and DBS should not compete against one another. The future is matching the right therapy to the right person at the right time in their disease journey. The next decade will likely teach us that lesioning and stimulation are complementary tools. Understanding when to use each may be every bit as important as understanding how they work. onlinelibrary.wiley.com/doi/10.1111/j.… #parkinson #tremor

Join the revolution in interdisciplinary neurological care at the Norman Fixel Institute for Neurological Diseases at the University of Florida. We believe the person living w/ disease is the sun, and every member of the care team orbits around helping them live their best possible life. If you are a social worker who believes care should be coordinated, compassionate and deeply human, this is your opportunity to help redefine what Parkinson’s disease, dystonia, Alzheimer's, ALS and movement disorders care can look like. Work side-by-side w/ neurologists, therapists, neuropsychologists, nurses, researchers and families in one truly integrated environment. If you believe the person w/ disease is the sun, then apply for this job: explore.jobs.ufl.edu/en-us/job/5394…

Amazing!!

Michael Okun @MichaelOkun

5 months ago

Tears of alpha synuclein? Parkinson’s disease detected in your tears: a new window into brain biology? What does alpha synuclein seeding mean? It refers to a process where tiny misfolded proteins act like templates that trigger other proteins to misfold, allowing scientists to

2 21 58 4K 17

The people have spoken and the company is listening. We have reached a public health milestone. “For decades we have warned that certain pesticides increase the risk of Parkinson’s and other serious diseases. This moment proves that advocacy, data and courage can change the trajectory of disease.” "Fewer people are going to develop Parkinson’s disease in the future.” "The voices of the Parkinson’s community, the voices of those who’ve been highlighting the toxic effects of this weed killer … are being heard and they’re having an impact.” Folks w/ Parkinson's, "tell your story," as that is the best way to create impact and contribute to the PLAN. pdplan.org theguardian.com/environment/20…

Hey friends,, Jumping on the trend and having fun with this caricature trend… hope you like it and stay tuned for some fun flashbacks of the 10 years. #teamfoxdetroit10 #michaeljfoxorg #teamfoxmjff #parkinsonsdisease #followers

10 years strong! Save the dates as we celebrate a decade of impact, community, and movement in support of Parkinson’s community in the Metro Detroit area &The Michael J. Fox for Parkinson’s Research. #teamfoxdetroit10 #10yearsstrong #act4pd #parkinsonsawareness #strongtogether

The vestibular system.

Fix your sleep before it fixes you. ✅

The brain cleans itself during sleep. 🧠💤 📹: xavork

Does deep brain stimulation change your dreams? When brain circuits meet the night shift what happens?Deep brain stimulation or DBS refers to a therapy where small electrical signals are delivered to specific brain areas to change possibly abnormal activity. Joswig and colleagues describe in a new paper in World Neurosurgery how deep brain stimulation may influence dream content in folks w/ Parkinson’s disease by altering brain networks involved in dreaming. Key points: – Dream and nightmare frequency did not change significantly after deep brain stimulation. – Dream content shifted toward fewer negative emotions and aggressor themes and more positive elements such as more friendly roles familiar settings as well as 'dreamer success.' – Sleep duration interruptions and REM sleep behavior disorder symptoms remained largely unchanged after surgery. My take: This is a fascinating window into how neuromodulation may reach beyond movement and into the emotional landscape of sleep. Deep brain stimulation did not simply turn dreams up or down. It appeared to reshape their tone. This reminds us that Parkinson’s is a whole brain condition and that therapies may influence lived experience in unexpected ways. Of course the study was a very small sample. Here are 5 points that resonated w/ me: 1- Dreams may reflect underlying brain network health, not just sleep quality. 2- Deep brain stimulation can shift emotional balance in dreams even when sleep metrics stay the same. 3- Reduced negative dream themes may matter for mood well being and caregiver experiences especially at night. 4- These findings highlight how potentially closely motor limbic and default mode networks are linked. 5- Larger studies are needed but this work opens the door to thinking about nighttime experiences as meaningful outcomes for folks receiving advanced therapies. sciencedirect.com/science/articl… @FixelInstitute @ParkinsonDotOrg @DBSThinkTank @SfNtweets @neurosurgery @TheJNS

Can Christmas calm the Parkinson's brain? Spoiler alert: YES, we can prove it w/ brain signals recorded from actual persons w/ Parkinson's implanted w/ DBS devices. Beta activity refers to a brain signal measured in the subthalamic nucleus that frequently rises when Parkinson’s symptoms are worse and falls when symptoms improve. Feldmann, Neumann colleagues describe in a paper in Movement Disorders how Christmas alters brain signals recorded from deep brain stimulation systems in the setting of Parkinson’s disease. Key Points: - Christmas Eve was associated w/ a consistent reduction in subthalamic beta activity when compared to non festive days. - The strongest signal changes occurred in the late afternoon and early evening, which is a common time for social gathering and celebration. - Brain network analyses showed these changes were linked to motor circuits targeted by deep brain stimulation. My take: Social context matters when it comes to brain signals and to disease. I love this paper and for those of you celebrating Christmas today just know it is good for your brain. Here are 5 points that resonated w/ me: 1- Everyday life events like holidays can change brain signals tied to Parkinson’s symptoms. 2- Positive experiences such as social connection, food, music and celebration may increase dopamine related activity. 3- Brain sensing technology facilitates health care providers seeing how real world behavior can affect the Parkinson’s brain. 4- Adaptive DBS systems will need to account for lifestyle patterns, not just for symptoms on clinic visits. 5- Joyful activities are not just meaningful emotionally, they may also influence brain biology in the setting of Parkinson’s and likely beyond. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md… @movedisorder @FixelInstitute @ParkinsonDotOrg @PdAvengers @DBSThinkTank @SfNtweets @JAMA_current @NEJMClinician @NEJM

Give today. Share the mission. Help change the future of Parkinson’s. teamfoxinthed.com #GivingTuesday #TeamFoxDetroit #MichaeljFoxOrg #EndParkinsons #HopeInProgress

keyboard_arrow_left Previous keyboard_arrow_right Next

Small habits, big changes, start today

#Coffee & Parkinson’s, what’s the connection? ☕ Hear from Dr.@MichaelOkun and learn more in THE PARKINSON'S PLAN. @RayDorseyMD Preorder now + get 5 FREE items from the 'Parkinson’s 25' checklist: bit.ly/4nCvN9d #Parkinsons #Parkinsonism #Parkinsonsdisease

@MichaelOkun Thank you for peeling back another layer of Parkinson’s.

Do you know the 2025 update on vestibular dysfunction in Parkinson’s? Does dizziness plague you? New evidence highlights how the balance system (vestibular system) may play a bigger role in Parkinson’s than we thought. A systematic review was conducted on over 100 studies revealed that vestibular signs and symptoms were common, however too often overlooked in both diagnosis and care. Key Points: - Nearly 40% of folks w/ Parkinson’s showed vestibular dysfunction, including nystagmus, oculomotor changes, abnormal vestibular evoked potentials and postural control challenges. - Dizziness was the most frequently reported vestibular symptom and this was followed by vertigo and balance problems. - Six clinical tools were rated as recommended for evaluating vestibular issues in Parkinson’s. - These included the sensory organization test, DHI, ABC scale, BBS, TUG and MiniBESTest. My take: We get a ton of questions at the Parkinson's Foundation about vestibular dysfunction and dizziness. I was grateful to see this article appear in the literature. Here are 5 points that resonated w/ me from their work: 1- Vestibular dysfunction is common in Parkinson’s and may result in dizziness, imbalance or falls. 2- Not all dizziness in Parkinson’s comes from having a 'low blood pressure.' The vestibular system could be a hidden culprit. 3-Balance relies on vision, sensation and vestibular input. When vestibular function falters, falling becomes more likely. 4- Specialized tests can help uncover vestibular challenges, however awareness is the first step. 5-Addressing vestibular dysfunction will likely open new treatment and rehabilitation pathways for Parkinson’s. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md… @ParkinsonDotOrg @FixelInstitute @SfNtweets @movedisorder @AANmember