Wennerberg Lab @WennerbergLab
#UCPH_BRIC bric.ku.dk/research-group… Copenhagen, Denmark Joined June 2017-
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Great to see the work by talented @SarangTalwelkar in collaboration with @WennerbergLab now in press. Biggest thanks to all the funders, particularly @SuomenAkatemia and @HiLIFE_helsinki HIPOC. @FIMM_UH
🌷Our May issue is out🌼 📙buff.ly/3VMvKdx 🧬Cover: #cfDNA shallow whole-genome sequencing monitoring of tumor fraction & somatic copy number 📷Explore Articles on #Immunology #Chromatin #PDL1 #LCSM #NSCLC #BrainMetastasis #ALKfusion #Mitochondria #Immunotherapy #qPCR
We would also like to thank all of our great collaborators, our funding and all of the #ovariancancer patients who kindly agreed to provide the tissue for the study. (3/3) @AnnaVaharautio @Sampsa_H @mijohy @matiasmfalco @KariLavikka @KaisaHuhtinen @OlliCarpen
Here’s the thread describing the results of the work, from when we published it as a preprint: (2/3)
We’re very happy to see our work developing what we think is a new state-of-the-art approach to develop high-grade serous ovarian cancer organoids now out in Developmental Cell. The efforts were brilliantly driven by @wojtsen with the support of many great collaborators. (1/3)
Online now: A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids dlvr.it/Snbt6K
Nice work by the @WennerbergLab: A platform for efficient establishment and drug-response profiling of high-grade serous #ovariancancer @wojtsen @AnnaVaharautio organoids cell.com/developmental-…
Out in @Dev_cell: Massive effort by @wojtsen from @WennerbergLab led to >50% success rate in #organoids growing in #OvarianCancer. Genomics and #scrnaseq data show close resemblance to tumors. Glad to be a part of this study. @deciderproject in action 💪 authors.elsevier.com/sd/article/S15…
For those at #AACR2023, @wojtsen will present some exciting HGSC organoid data. Starts at 16:07 local time. #FPMatAACR23 #HGSC #ovariancancer #organoids
Don't miss this important session today on Novel Targets, Biomarkers, and Models for Cancer, with a presentation by @wojtsen, info below! #FPMatAACR23 #AACR23
The Minisymposium on Novel Targets, Biomarkers, and Models for Cancer (MS.TB05.01) will include a talk from @wojtsen on an ovarian cancer organoid-based platform for patient stratification When: April 18, 2023, 2:30 PM - 4:30 PM Where: Room W304 A-D abstractsonline.com/pp8/#!/10828/s…
We’re looking forward to another day of discussions and planning for the second half of the project today!
Midterm evaluation meeting for the PARIS (Precision drugs Against Resistance In Subpopulations) project - On the way to Institute Pasteur campus. #ovariancancer @bennos @AnnaVaharautio @WennerbergLab @erapermedparis @Gynkreft @reachoutinova @PrecosL @haukeland_no @medofak_uib
@afarkkila @ronny_drapkin @kristerwennberg @Cancerfonden @karolinskainst An outstanding meeting so far. Eagerly anticipating day 2, including a presentation by @afarkkila!
“Giantly” inspired by being part of a winning team at the @OvaCure_COCT Innovation Challenge 2022! #OvCa @rottapel, @regenberg_lab, @AnilSoodMD, Jinsong Liu,@wvdriel, Marie Krarup, @m_boegsted
A great symposium that unfortunately was over much too fast. Next time I’m Copenhagen!
Functional precision medicine for blood cancer symposium ongoing in Helsinki @HelsinkiUniMed @EHA_Hematology @iCAN_Finland helsinki.fi/en/conferences… Great speakers and presentations, keynote talk by @RaviMajetiMD @majetilab
It's that time of the year again! The DHL relay 2022! Great team effort and thanks for a good time! @WennerbergLab @UCPH_BRIC #DHLstafetten
Summer vacation times are coming and it’s also time to think about what to do after the summer. There’s a position open in the BRIC high content CRISPR screens core facility! employment.ku.dk/staff/?show=15…
This should be an outstanding meeting. Very much looking forward to it!
Functional precision medicine for blood cancer symposium ongoing in Helsinki @HelsinkiUniMed @EHA_Hematology @iCAN_Finland helsinki.fi/en/conferences… Great speakers and presentations, keynote talk by @RaviMajetiMD @majetilab
Excited to give a talk at Corning’s 3D Cell Culture Day tomorrow :).
Dr. Wojciech Senkowski has a decade of experience in 3D cell cultures. In the upcoming Corning 3D Cell Culture and Bioprocess User Days, he will present a novel approach for HGSC organoid model development, validation and profiling. Join the discussion: ms.spr.ly/6013br3JJ
This time we are looking for candidates too!
Dr. Wojciech Senkowski has a decade of experience in 3D cell cultures. In the upcoming Corning 3D Cell Culture and Bioprocess User Days, he will present a novel approach for HGSC organoid model development, validation and profiling. Join the discussion: ms.spr.ly/6013br3JJ
For more details, check out the preprint! PS. Some organoid cultures will soon be available to everyone through @AuriaBiopankki biobank! (The end)
Finally, limitations of the work: 1. We still don't know how to grow 45% of HGSC samples as organoids in a long-term. Probably a 3rd medium will be needed🤷 2. More extensive in vitro/in vivo drug response correlation study is needed for #precisionmedicine applications (15/n)
❓Why is it important to design new methods for #organoid culture? ❓How much should we validate our experimental models? ❓What about correlating #organoid drug responses to patient outcomes? A🧵on the results in our newest preprint on high-grade #OvCa organoids⬇️ (1/n)
Our next-gen method for generating #organoids from high-grade serous #OvCa is now available on @biorxivpreprint. Genetically and phenotypically relevant stable organoids from cryopreserved material. Great effort led by @wojtsen. biorxiv.org/content/10.110…
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