Serini Lab @adhynamic
Our lab tries to grasp the molecular mechanisms by which cells adhere to and move through the body environment in cancer, vascular and rare genetic diseases irccs.org/cell-adhesion-… Candiolo Cancer Institute, IT Joined March 2013-
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Serini Lab retweeted
Mechanobiological mechanism of cyclic stretch-induced cell columnarization dlvr.it/TKdwss
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Serini Lab retweeted
Local weakening of cell-extracellular matrix adhesion triggers basal epithelial tissue folding Andrea Valencia-Expósito, María Martín-Bermudo et al embopress.org/doi/full/10.10…
@paoloarmando83 @VersitiResearch @ZanivanLab Thank you Paolo!
Glad to share our last manuscript on a luminescent sensor we created to unveil novel potentially actionable regulators of β1 integrin activation in vascular endothelial cells and angiogenesis. Great collab w/ Jieqing Zhu Lab @VersitiResearch @ZanivanLab doi.org/10.1016/j.celr…
Serini Lab retweeted
September issue of @JCellBiol also contains our new paper on TLNRD1 (talin rod domain containing 1) protein and its role in the Cerebral Cavernous Malformation complex. rupress.org/jcb/article/22… @guijacquemet @LivUniISMIB @biokent @UniTurku
Our September issue is out! hubs.la/Q02N4zdK0 🔬 The cover shows the heart (cardiac tube) of a 20-day old adult #Drosophila stained with phalloidin (red), while adjacent pericardial cells are marked by dorothy-GFP (green). From @gera_jayati et al (hubs.la/Q02N4zxk0)
Serini Lab retweeted
Our paper is now out!! Great and exciting collaborative work. Thank you all. PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination aacrjournals.org/cancerimmunolr…
Serini Lab retweeted
We just updated our preprint, "The structure of an Amyloid Precursor Protein/talin complex indicates a mechanical basis of Alzheimer's Disease" to include beautiful new proximity ligation data of talin and APP in neurons. 😍 @jcl_lambert @LivUniISMIB biorxiv.org/content/10.110…
Serini Lab retweeted
Now online! Ligand binding initiates single-molecule integrin conformational activation dlvr.it/T791P4
Serini Lab retweeted
Rab7 deficiency induces lysosome formation from recycling endosomes leading to an increased degradation of cell surface proteins biorxiv.org/content/10.110…
Serini Lab retweeted
Check out our latest review in which we discuss the recent exciting discoveries on single-cell and collective ERK signaling dynamics!
Check out our recent review on the ever-evolving #MAPK/#ERK signaling dynamics. It never ceases to amaze me how one of the most studied signaling pathways continues to deliver new surprises. Thanks to @paoloarmando83 for writing this with me. sciencedirect.com/science/articl…
Serini Lab retweeted
Very pleased to share our latest preprint on MAPK dynamics and cell fate decisions in lung cancer biorxiv.org/content/10.110… . Does EGFR mutation mean MAPK is always on? NO, it shows dramatic pulses👇1/4
Serini Lab retweeted
💥Check out our latest work just out @NatureComms 🔬#Platelets shape the outgrowth of #metastasis, even growing & established foci. 🎯We further identified #targets and tools with therapeutic potential rdcu.be/dHL7i #mouse #zebrafish #imaging #Immunology #hemostasis
Serini Lab retweeted
Thrilled to announce our latest research just published in @NatureComms! We investigated how therapy induces therapy resistance via cell state transition and vessel co-option in glioblastoma. (1/11) nature.com/articles/s4146… #GBM #btsm #Research
Serini Lab retweeted
Our latest paper! A promising avenue for therapeutic intervention in fibroses, characterized by excessive ECM production, via targeted inhibition of TANGO1-mediated ER export. TANGO1 inhibitors reduce collagen secretion and limit tissue scarring nature.com/articles/s4146…
Serini Lab retweeted
Thrilled to see our latest work “Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function” led by Alice Santi and @emilyjkay1 on the cover of @scisignal. Beautiful images by @BairBeatson Paper here 👇🏻 science.org/doi/10.1126/sc…
Serini Lab retweeted
Looking very much forward to my visit to @CIBIO_UniTrento of Thu July 20th, meeting and discussing with its scientists
We are glad to host "In search of normality: looking for molecular strategies to repair #cancer blood vessels" a seminar by @gserini 🗓️ July, 20th at 2.30pm 🏛️ Room A104, Povo 1 ℹ️ webmagazine.unitn.it/node/117297/ #blood #bloodtumor
Serini Lab retweeted
We are glad to host "In search of normality: looking for molecular strategies to repair #cancer blood vessels" a seminar by @gserini 🗓️ July, 20th at 2.30pm 🏛️ Room A104, Povo 1 ℹ️ webmagazine.unitn.it/node/117297/ #blood #bloodtumor
Serini Lab retweeted
Interested in a Post-doc @IvaskaLab @BioscienceTurku working on novel anti-invasive barriers in BrCa - cutting edge cell biology/imaging/HTS/clinical collaboration? Watch this space! We will be shortly opening a call a post-doc @WorldwideCancer granted 3 year funding
Serini Lab retweeted
Online today! 👉Mutated #AxonGuidance gene #PLXNB2 sustains growth and invasiveness of stem cells isolated from #CancerOfUnknownPrimary By @GiraudoEnrico, L. Tamagnone & colleagues @fpoirccs @unito @Unicatt 🗞️Read #openaccess: doi.org/10.15252/emmm.…
Serini Lab retweeted
Our paper is now out!! Great and exciting collaborative work. Thank you all. x.com/EmboMolMed/sta…
Online today! 👉Mutated #AxonGuidance gene #PLXNB2 sustains growth and invasiveness of stem cells isolated from #CancerOfUnknownPrimary By @GiraudoEnrico, L. Tamagnone & colleagues @fpoirccs @unito @Unicatt 🗞️Read #openaccess: doi.org/10.15252/emmm.…
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