Guido Appenzeller @appenz

At a16z investing in AI & Infra. 2x founder & CEO. CTO at Intel & VMware. CPO at Yubico. Tweets are my own. guido.appenzeller.net Silicon Valley, CA Joined January 2008

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Guido Appenzeller @appenz

14 hours ago

Great article by @extrabrunch on Netris. GPU cloud networking really is different (and hard). techcrunch.com/2026/06/25/net…

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Guido Appenzeller @appenz

14 hours ago

@abenik @netris_io @alex_saroyan Yup, building networking management/control planes does not happen over night.

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Super excited to announce that we are leading the Series A in @netris_io. Every technology cycle changes the underlying infrastructure. And Netris has build the Networking Software Stack for AI. We are excited to partner with @alex_saroyan, Arsen Arakelyan and Tigran Martirosya! a16z.com/announcement/i…

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57 years ago

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Netris @netris_io

a day ago

Netris has raised its $15 million Series A, led by @a16z. Guido Appenzeller (@appenz) led the round and is joining our board, with fellow a16z partners Martin Casado (@martin_casado) and Raghu Raghuram (@RaghuRaghuram) behind the investment. Together, they're the team behind the network virtualization that reshaped the modern data center — Nicira, NSX, VMware. They solved networking for the data center. Netris is doing it for AI. Eight years ago, that bet looked wrong. We believed the network would become the hardest problem in computing, and that nobody outside the hyperscalers had the tools to solve it. The hyperscalers had built that automation for themselves — armies of engineers, custom systems. Everyone else was stuck. So we built a platform to put it within reach of any operator. Most investors didn't see it. Most of the industry didn't either. But the operators actually running networks did — they started choosing Netris long before AI was on anyone's roadmap. Then the AI buildout hit, and the network became the bottleneck for the entire industry. A single GPU cluster runs across multiple network fabrics at once — Ethernet, InfiniBand, NVL72 — each with its own control plane, spanning hundreds or thousands of switches. None of it was built to work as one, and the automation tools that came before were never designed for it. One misconfiguration can take an entire cluster down. It was the exact problem we'd spent years solving — and the platform was already built for it. Netris automates network operations across every fabric and delivers true multi-tenancy through hard isolation (enforced on networking hardware). Operators can now run shared GPU clouds, maximize GPU utilization, and provision new tenants instantly. In the last 12 months, Netris experienced 800% ARR growth and reached 35+ live deployments and growing — more live deployments than all other network automation vendors combined. The largest AI clouds in the world have chosen Netris: neoclouds, sovereign AI operators, and AI factories. Huge thanks to the Netris team, our customers, investors, @nvidia, and our ecosystem partners, including @MirantisIT, @rafaysystemsinc, @RedHat, @spectrocloudinc, @vclusterlabs, and @HPE. The AI buildout is just beginning. Netris has been ready for this for eight years. Read the press release: netris.io/blog/andreesse…

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Guido Appenzeller @appenz

2 days ago

@SemiAnalysis_ This would be a lot funnier if there were not for the number of start-ups that have pitched they will do this. Raise seed, tape-out after 9 month, first deliveries after 12. I want to believe, but chips are hard!

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Guido Appenzeller @appenz

2 days ago

@maticrobots Congratulations!

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Guido Appenzeller @appenz

2 days ago

Congratulations Matic Team!

Matic Robots @maticrobots

2 days ago

Congrats to the Production team on building 10k Matics!

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Guido Appenzeller @appenz

6 days ago

@maticrobots Free marketing for your robots on Reddit 😁 This is why home robots need to be vision based. reddit.com/r/shittyrobots…

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Mirelo @MireloAI

a week ago

Today, we launch Mirelo SFX Plugin for @Roblox You can now generate scene-aware, custom sound effects like collisions within seconds based on the context of your layout and objects #RobloxDev #RobloxDevs #gamedev #Roblox

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Guido Appenzeller @appenz

a week ago

@mlejva 100% agreed

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Guido Appenzeller @appenz

a week ago

This is kind of cool. Amazing how Sandboxes have evolved from a mini-VM to an management primitive for agents and tools.

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Guido Appenzeller @appenz

2 weeks ago

This is misunderstanding AI. It’s an infrastructure technology that will be used by everyone. When the CPU (in the 70s) or the internet (in the early 90s) proliferated, you could have written the same about home computer use or early web browsers. How it’s a choice, and some will use it some won’t. But that’s not what happened. Infrastructure technologies become ubiquitous. Everyone uses CPUs and networking today. The may just no longer notice.

Gabriel Weinberg @yegg

2 weeks ago

No, everyone is not using AI for everything. gabrielweinberg.com/p/people-are-c… People are consuming AI like they eat meat: some are embracing it, some are limiting their use of it, and some are avoiding it altogether.

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Guido Appenzeller @appenz

2 weeks ago

@pollenrobotics If you sign up for the Pollen Robotics Discord, you get a message that new accounts are read-only for a specific amount of time. You make users with a defective product wait to even file a claim.

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Guido Appenzeller @appenz

2 weeks ago

@pollenrobotics Asking your customers to submit warranty claims via Discord, and then disabling posting on your Discord for new accounts is a bit of a dick move. Is this is the reputation you want to build?

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Guido Appenzeller @appenz

2 weeks ago

@Bensign Yeah, Jetstream is doing funny things today.

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Guido Appenzeller @appenz

2 weeks ago

It's silly how the @arena and @ArtificialAnlys leaderboards for open-weights image generation differ right now. - @ideogram_ai is #1 vs. #8 (really?) - @nvidia Cosmos is #8 vs. #1 - @bfl_ai is #3 vs #6 I may be biassed, but @arena seems a lot closer to reality.

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Guido Appenzeller @appenz

3 weeks ago

There are good examples what happens if you don’t do this. I grew up in Germany and in the late 1980s/early 1990s it was illegal to operate private modems on the phone network. You had to rent them, and cost was prohibitive. The early ISPs (e.g. Subnet e.V. In Karlsruhe) had members live in fear of police showing up to confiscate their illegal modems. It seems silly today, but back then it inhibited Internet growth and Germany never caught up to the US.

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Shuo Yang @Andy_ShuoYang

a month ago

Flash-KMeans was only the beginning. Today, from the Flash-KMeans team, we are releasing FlashLib — a GPU library for fast, predictable, agent-ready classical ML operators. Up to 26× on KMeans, 19× on KNN, 40× on HDBSCAN, 208× on TruncatedSVD, 47× on PCA, 147× on exact t-SNE, and 49× on MultinomialNB over state-of-the-art (cuML). Blog: flashml-org.github.io Code: github.com/FlashML-org/fl…

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Genesis Molecular AI @genesismolai

3 weeks ago

Welcome to the team, Han Wang! Han joins as VP of Engineering, bringing expertise in computational mathematics, national security, and cybersecurity, with hands-on experience leading large-scale engineering infrastructure from Lawrence Livermore National Laboratory to the U.S. Army Reserve Cyber Corps. Han also co-founded YC-backed Upfort and most recently served as Head of Engineering, Infrastructure at Numeral. His expertise comes at a pivotal moment: as we build the infrastructure to train and scale our foundation models like Pearl, having the right engineering leadership in place is critical. Learn more and explore our open roles: genesis.ml/careers