Jamesb @experilearning

biocompute experimentallearning.xyz London, UK Joined October 2020

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Jamesb @experilearning

2 weeks ago

I stopped here because the dataset started to feel like the main limiting factor. I would be keen to people's ideas about what sort of setup could elicit a truly interesting language with novel ideas?

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Jamesb @experilearning

2 weeks ago

It did come up with some more interesting ideas, eg. adding unions and intersections to combine and subtract shapes. It chose to use signed distance fields for its CAD engine. To bootstrap programs for each target it used program search over its DSL.

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Jamesb @experilearning

2 weeks ago

Quick experiment - a CAD language is a compressor for geometry; if you ask claude to design a language to maximally compress a set of STLs, what language does it come up with?

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Jamesb @experilearning

2 weeks ago

@yeahwouh nice, definitely gonna check it out

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Jamesb @experilearning

3 months ago

Science begins with myths becuase by the standards of the consensus "best current theory" which defines what we think of as "real" any deviation will appear like fantasy

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Jamesb @experilearning

3 weeks ago

@fsfarimani I'm sure you can! I used build123d because that's what I used in the past but I imagine it would work with any code -> CAD language

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Jamesb @experilearning

3 weeks ago

you can convert pesky STL files into human editable STEP files using claude + build123d

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Jamesb @experilearning

3 weeks ago

@makeshifted Oh interesting I didn’t know build123d had a function for that. I checked the logs and scripts it made - can’t see any references to those docs or detect_primitives

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Jamesb @experilearning

4 weeks ago

bit dramatic but I do feel neglecting any kind of reading / learning in favor of frantic MAN OF ACTION over the past 3+ years has caused significant brain shrivel, please send material (blogs/books/whatever) to restore me to full turgidity

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Jamesb @experilearning

4 weeks ago

experimentallearning.xyz/p/vibe-coding-… 2/2

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Jamesb @experilearning

4 weeks ago

Did a quick blog post about the rise of vibe hardware, featuring my dad who's been flexing on me with some modular synthesiser stuff I don't understand (what's a vactrol?) 1/2

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Seth Howes @SethSHowes

3 months ago

I’ve wanted to do this for a decade. But I never did - I refuse to give any company my DNA. It is me. So this week I sequenced my genome entirely at home. Literally on my kitchen table. I never exposed my DNA sequence to the internet. Not at any point. I used a MinION to do the sequencing (it’s smaller + weighs less than an iPhone). I used open-source DNA models for the analysis (Evo2 and AlphaGenome) running locally on a DGX Spark and Mac Studio. I traced mechanisms behind my family’s multigenerational autoimmune conditions that no clinician has been able to understand. When I set out to do this I didn’t know if it would actually work. It does. Your genome is the most private data you will ever have. You probably shouldn’t let it leave your house.

Patrick Collison @patrickc

3 months ago

I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that

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Jamesb @experilearning

3 months ago

Top centaur-era skill = leveraging massive search. How fast can you spam attempts in parallel and trial and error your way to success. Make trials as fast+cheap as possible, learn from failure, apply computational approaches creatively to domains people aren't using them

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Jamesb @experilearning

3 months ago

Daily progress #6 + utilisation rate is going up, the goblin is satisfied - but more can be done - the big unlock is going to be increasing walkaway time so I can run overnight with 100% confidence

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Jamesb @experilearning

3 months ago

@iRammohanSharma the set of automated lab equipment we have

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Jamesb @experilearning

3 months ago

Daily progress #5 + made a script to track what % of the day our workcell is running + my sole aim is to make number go up + had fun benchmarking claude against himself at colour mixing optimisation + the system feels robust enough to leave running overnight 💪