Thomas Paul @jmaykey

Wild to see $AMD now trading at nearly 3x $NVDA forward earnings multiple with Nvidia at ~20x despite 90% AI GPU share, 75% gross margins and a path to $1T in cumulative Blackwell and Rubin revenue through 2027. The market is paying AMD for rate of change after landing $META, $ORCL and OpenAI gigawatt commitments but the real decoupling came from the CPU bottleneck trade. GPU deals re-rated AMD but the CPU trade is what helped it decouple from Nvidia as EPYC gains pricing power into tighter supply and hyperscalers “gobbling CPUs” for agentic workloads.

While Bitcoin gets a lot of attention, it hasn’t played the safe-haven role many expected. In my view, there are a few reasons why. First, Bitcoin lacks privacy. Transactions can be monitored and potentially controlled, which is why central banks aren’t looking to hold it. Second, it also has a high correlation with tech stocks. When investors get squeezed in other areas of their portfolio, they sell their Bitcoin to cover it. Third, it’s a relatively small and controllable market, whereas gold stands alone. There is only one gold. Ultimately, gold is more widely held, deeply established, and still plays a central role in the global system.

Alex Karnal (@alex_karnal) is the most talented bio and healthcare investor I've ever met. He's spent 20 years in the industry and says 2025 was the single most exciting year he's seen. The start of a once-in-a-lifetime, trillion-dollar revolution in public health. He explains how few people realize we already have the medicines to prevent our deadliest diseases. The problem is that almost no one takes them. There's a population of people born with a mutation that means their bodies don't produce a protein called PCSK9. Their lifetime risk of cardiovascular disease is 88% lower than yours. Pharma turned that genetic advantage into a drug. It's been approved for years, but the number of people taking it is still vanishingly small. Partly because high cholesterol is a silent killer. You feel nothing, right up until you have a heart attack. And partly because the health system makes it punishingly hard to stay on a preventive drug like a PCSK9 inhibitor. In other words, the medicine works, but the system around it doesn't. That's what's starting to change, and in this episode, Alex explains why. We discuss the "health stack" he believes can add a decade to most lives, why oral GLP-1s are breaking every adoption record in pharma, peptides and citizen pharmacology, and what AI is doing to drug discovery. I wish I had an "Alex" for every interesting topic. We've been having versions of this conversation for over five years, and every single one is as clear and as useful as this one. Enjoy! Timestamps: 0:00 Intro 1:00 The State of Modern Medicine 5:00 Designing the Modern Health Stack 12:17 The GLP-1 Inflection Point 19:18 The Biological Mechanisms of GLP-1 30:36 Overcoming Frictions in Healthcare 34:19 Cardiovascular Disease 44:04 Addressing Alzheimer's 47:04 The Future of Cancer 57:33 Drug Discovery 1:05:25 AI and Scientific Super Intelligence 1:14:40 Citizen Pharmacology and the Peptide Movement 1:18:13 Background and Career Journey 1:31:09 Braidwell's Investment Approach 1:33:30 The Kindest Thing

$PLTR $AMD $TSLA $XYZ $GRAB $HIMS $META $GOOGL $AMZN The legend Howard Marks is back this morning on CNBC On Private Credit, Equity Market and Economy $QQQ $SPY $DIA Source: CNBC

Mike @MikeLongTerm

3 months ago

$PLTR $AMD $TSLA $XYZ $GRAB $HIMS $META $GOOGL $AMZN | Volatility is NOT Risk 🧵 It is Sunday, so we have to learn from the legand Howard Marks! Howard Marks has repeatedly argued that volatility is not risk despite it being the standard academic definition he was taught early

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This 1 hour Yale lecture will teach you more about options trading & the exact models Hedge Funds use than most people learn in their entire careers on Wall Street. Bookmark this & watch, no matter what. It’ll be the most productive start for your week. Then read article below.

Roan @RohOnChain

3 months ago

x.com/i/article/2043…

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The market's character is still one of a bear market or cyclical correction; strong open, fade into close and major average living below the 200-day line. Before a reliable bottom can be established, we need to see better price and volume action, including better action from breakout names forming bases. We are clearly NOT out of the woods yet. The market backdrop is one where sentiment has improved with rising pessimism, but not a full capitulation. The VIX has reached bear warning levels, but remains below true washout extremes. A volatility washout is not required for a bottom, but would add conviction. Bullish Scenario --The war ends --Oil prices recede --Stagflation concerns ease --Central banks continuing their easing trajectory Under this scenario, we would expect: -A broadening market advance -Emergence of new leadership from sound bases -A Follow-Through Day (FTD) on the NYSE and/or NASDAQ confirming institutional buying with little in the way of immediate distribution -Significant drop in volatility Bearish Scenario --The war persists or escalates --The Strait of Hormuz remains disrupted --Oil prices make new highs --Stagflation becomes evident in hard economic data This would likely result in: -Limited general market rally attempts with most breakout stocks failing -Lack of follow-through from breakout names -Further deterioration in breadth and leadership -Dearth of setups in buyable position -Continued elevated volatility and distribution In that case, sentiment would likely need to reach higher levels of pessimism before a durable market bottom could form. In its absence, and end to the factors that are pressuring the market could cause the market to bottom in less dramatic fashion.

Ray Dalio gives a 39 minute master class on wealth creation.

Steve Jobs literally predicted the iPhone, the Internet, AI and the next 50 years of technology in a single speech from 1983:

Charlie Munger’s 1998 Harvard speech is the ultimate cheat code for life. He compressed 74 years of billionaire wisdom into just 30 minutes. Most people spend 4 years in college and learn less than what’s in this video. Save this video, you will come back to this.

My favorite @perplexity_ai prompt I’ve made for traders. Feel free to copy and use. ———————————————— Please analyze [TICKER] for me and provide the following, concise and clearly organized: 1. **Explain what the company does in like I'm 12 years old** - three short bullet points about what it does and any helpful relatable examples and analogies. 2. **Professional summary (max 10 sentences)** - industry, main products/services, primary competitors (list tickers), notable metrics or achievements, competitive advantage/moat, why they are unique and if they are a biotech provide if they have a commercial product or in clinical stages. 3. In a table, provide the follwoing: * Any hot theme, narrative or story of the stock * Any catalysts (earnings, news, macro) * Any significant fundamentals (huge growth in earnings or revenues, moat, unique product or service, superior management, patents etc) 4. **Show all the main news/events for the last 3 months:** - Use a bullet-point table for: - Date (YYYY-MM-DD) - Event type (Earnings, Product Launch, Analyst Upgrade/Downgrade, etc.) - Short summary (max 1-2 sentences) - Direct source link - Mark any major price-moving events (surprise earnings, large guidance shift, top-tier analyst actions). 5. **Mention any recent insider buys/sells or institutional filings if visible.** 6. **Summarize how the stock is moving vs. main competitors and overall sector trend in past month (up/down).** 7. **Flag upcoming catalysts (earnings, product launches, regulatory events) in the next 30 days.** 8. **Note any changes in analyst price targets for this ticker during the period above.** - Format for easy review. If possible, use tables for events and peer moves. - Respond in clear, concise, easily readable style for use in trading decisions. Overall, Focus on the reasons why the stock can make a big move in the future - earnings, sales, guidance, product launches, analyst upgrades/downgrades, insider buying especially from CEO/Founder and executive team, partnerships, and sector/news catalysts. I want to focus on stocks with catalysts and themes as catalysts are the cause of big moves in the stock market. Finally, discuss and bring up any relevant previous perplexity queries and conversations.

The Kobeissi Letter @KobeissiLetter

5 months ago

BREAKING: Perplexity announces an advanced version of Deep Research, which beats both OpenAI and Anthropic in benchmarking tests. The AI race just keeps on accelerating.

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AOT Top Pick strategy update Week 5 Top Pick: $HL +4.26% 2026 YTD: +14.42% AOT Top Pick returns since inception: 2022 Results: +115.74% 2023 Results: +131.86% 2024 Results: +37.46% 2025 Results: +10.19% In case you didn't know, we don't update the Top Pick results on Twitter/X each week so make sure to keep the link below handy to view the Top Pick strategy results. They're updated at the end of every week! artoftrading.net/post/aot-top-p…

Here are my 4 most important @tradingview stock screeners that I use daily & weekly for FREE 👇 1) Best Winners Screener This is my core screener. The strongest stocks. Real leaders. High momentum, strong relative strength, clean trends. These are the names that can become multi-week winners if the market allows it. 🔗 tradingview.com/screener/KZAnx… 2) Daily Strong Screener Pure market feedback. I run this daily to see where money flows today. It tells me if strength is expanding or drying up — without opinions, without noise. 🔗 tradingview.com/screener/FfS5r… 3) Short Screener Especially important in downtrends. Extended stocks losing momentum, weak reactions, failed highs. I don’t guess shorts — I prepare for them. 🔗 tradingview.com/screener/PgvR2… 4) Pre-Market Screener Gap-ups, unusual volume, fresh catalysts. Not to chase — but to observe and prepare structured plans before emotions kick in. 🔗 tradingview.com/screener/B3i61… All of these screeners are free. No secrets. No fancy tricks. But here’s the truth: A screener doesn’t give you an edge. Knowing how to read it does. That’s why I walk my members through them again and again. Dozens of videos. A full webinar. Live explanations. Real examples. Screeners are tools. Experience turns them into a weapon. These patterns repeat. I’ve taught this process to thousands. You can learn it too.

@StockSavvyShay @threadreaderapp unroll

@BourbonCap @threadreaderapp unroll

$AMZN is a privately run economy hiding inside one ticker: • AWS AI stack: Trainium, Inferentia, Graviton & Bedrock which is the AI leverage the market still underprices • Advertising plumbing: Amazon DSP + retail media network tied directly to purchase data • Logistics as a service: FBA, Buy with Prime, Amazon Freight becoming third-party commerce infrastructure • Project Kuiper: satellite broadband as a long-duration optionality play alongside AWS • Health + data: One Medical + pharmacy + Care AI (early innings but very Amazon-ish land grab Amazing really is compute, commerce, logistics & data fused into one operating system.

There is no avoiding pain, especially if you're going after ambitious goals. Believe it or not, you are lucky to feel that kind of pain if you approach it correctly, because it is a signal that you need to find solutions so you can progress. If you can develop a reflexive reaction to psychic pain that causes you to reflect on it rather than avoid it, it will lead to your rapid learning/evolving. After seeing how much more effective it is to face the painful realities that are caused by your problems, mistakes, and weaknesses, I believe you won't want to operate any other way. It's just a matter of getting in the habit of doing it. #principleoftheday

𝗧𝗵𝗲 𝗟𝗲𝗮𝗱𝗶𝗻𝗴 𝗦𝘁𝗼𝗰𝗸𝘀 𝗥𝗶𝗴𝗵𝘁 𝗡𝗼𝘄: 𝗠𝗮𝗿𝗸𝗲𝘁 𝗟𝗲𝗮𝗱𝗲𝗿𝘀 $BE Bloom Energy $NBIS Nebius $HOOD Robinhood $CLS Celestica $CRWV CoreWeave $SYM Symbotic $STX Seagate $CRDO Credo Technology $INSM Insmed $MU Micron $PLTR Palantir $UI Ubiquiti $FIX Comfort Systems $NET Cloudflare $AMD AMD $CCJ Cameco 𝗡𝗲𝘅𝘁-𝗚𝗲𝗻 𝗟𝗲𝗮𝗱𝗲𝗿𝘀 $IREN IREN $SNDK SanDisk $LEU Centrus Energy $VSAT Viasat $APLD Applied Digital $KTOS Kratos $PL Planet Labs $PGY Pagaya $KRMN Karman $NXT Nextracker $TEM Tempus Al $FUTU Futu $MVST Microvast $AMSC American Superconductor $AVAV AeroVironment 𝗦𝗽𝗲𝗰𝘂𝗹𝗮𝘁𝗶𝘃𝗲 𝗟𝗲𝗮𝗱𝗲𝗿𝘀 $BETR Better Home $BMNR Bitmine Immersion $OKLO Oklo $TMC TMC the Metals Company $LTBR Lightbridge $GRAL Grail $OPEN Opendoor $QBTS D-Wave Quantum $UUUU Energy Fuels $CIFR Cipher Mining $ASTS AST SpaceMobile $NVTS Navitas Semiconductor $QS QuantumScape $AEVA Aeva Technologies $EOSE Eos Energy Here's the full list: fullstackinvestor.co/watchlist

This is Howard Marks. He is one of the best value investors alive. He just went on the My First Million Podcast and shared his investment strategy. Here are the 7 things you can't miss: 🧵

History shows us that having too much debt during an economic downturn leads to a classic, self-reinforcing cycle where: 1) The empire can no longer borrow the money to repay its debts 2) It prints a lot of new money, which devalues the currency and raises inflation 3) Living standards decline, leading to the rise of political extremism 4) Turbulent economic conditions undermine productivity and there is conflict about how to divide the shrinking resources 5) Populist leaders emerge pledging to take control and bring about order #principles #raydalio #history #debt