Melanie Machiels @mchiels
Radiation Oncologist @ Iridium Network Antwerp | Associate Professor @ University of Antwerp | #breastcancer #gynaecologicalcancer #brachytherapy Antwerpen, België Joined January 2022-
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Following433
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Melanie Machiels retweeted
🚨Highlights from #SABCS2024! Prof Dr @mchiels explores breakthroughs from the Rapid Fire Session 2: - Axillary management: Alliance 11-202 findings - Micrometastases & DFS: German Breast Group analysis - Faster radiotherapy boosts: ULTIMATE trial outcomes - TILs in ER-negative patients: Prognostic insights - Managing chemotherapy nausea: Olanzapine's efficacy
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Very honoured to present the interim-analysis of our ULTIMO trial at #SABCS24
Rapid Fire 2 #SABC24 ➡️ Ultrahypofractionated versus conventional fractionated sequential boost after whole-breast radiation therapy in breast cancer patients. One-year cosmetic outcomes of a randomized, controlled, phase 3 trial (ULTIMO) ☢️ @OncoAlert #OncoAlertAF
Melanie Machiels retweeted
📌Does Postmastectomy Radiotherapy in 'Intermediate-Risk' Breast Cancer Impact Overall Survival? 👉🏻10-Year Results of the BIG 2-04 MRC SUPREMO Randomized Trial: On Behalf of the SUPREMO Trial Investigators by Prof Ian Kunkler #SABCS24 #day3 @OncoAlert #OncoAlertAF #GeneralSession2
The interim-analysis of the groundbreaking EUROPA trial demonstrates what we all have been thinking: ⁃Much less AE’s in the RT arm ⁃Better HRQoL preservation in the RT arm Time for a paradigm shift! Congratulations @Icro_Meattini #SABCS24
Melanie Machiels retweeted
Thanks to @komop_tgkanker and all the people supporting it, @gzaziekenhuizen and the Iridium Network will be able to conduct 2 new trials: PRADA (@mchiels) and OligoRare (me and @Mat_Guc with @EORTC), trying to improve outcomes for cancer patients!
Melanie Machiels retweeted
Check out Dr. Paolo Tarantino @PTarantinoMD @DFCI_BreastOnc discussing top 5 takeaways from #SABCS23 including KATHERINE & INAVO120 #bcsm #HER2 #TNBC #BreastCancer full📽️on #VuMedi 👇 bit.ly/TOP5SABCS23
Proficiat @joostverhoeff!
Succession planning is key. Very happy that, after leading the #radonc department at @amsterdamumc for almost 30 years, @joostverhoeff has taken over. I have peace of mind and time for other tasks!
Elective node irradiation including IMN for all high-risk #breastcancer patients from now on!
Virtual Grand Rounds in Radiation Oncology January 10th 17:00 - 17:30 CET Prof. Carolyn Taylor: Effect of regional lymph node radiotherapy. An EBCTCG meta-analysis of 14,324 women in 16 trials Link to Zoom Meeting 👇 usz.ch/veranstaltunge…
Melanie Machiels retweeted
Presented at #ESMO23 data from the #Keynote756 trial showing an increased pCR rate with the addition of #pembrolizumab to neoadjuvant chemotherapy in patients with high-risk hormone receptor-positive HER2-negative #BreastCancer @myESMO @OncoAlert #bcsm
@joostverhoeff @amsterdamumc @bslotman Proficiat Joost!! Welverdiend!!
The past is a place to learn from, not to live in 🧐 Onwards with #genomicclassifiers for individualization of #Radiotherapy
LUMINA: 2.3% 5-yr IBTR in women ≥55 w/ G1-2 pT1N0 luminal A (ER≥1%, PR≥20%, HER2-neg, Ki-67≤13.25%) #breastcancer s/p lump w/o #radiotherapy. Path forward: #Genomic classifiers of individual RT benefit, not omitting based on clinicopathologic features. nejm.org/doi/full/10.10…
Melanie Machiels retweeted
Happy to have contributed to this excellent review led by @mchiels focused on using #TILs and genomic #biomarkers to individualize #radiotherapy in #breastcancer. thebreastonline.com/article/S0960-…
Has the time come to individualize #radiotherapy using #TILs and genomic #biomarkers?
Happy to have contributed to this excellent review led by @mchiels focused on using #TILs and genomic #biomarkers to individualize #radiotherapy in #breastcancer. thebreastonline.com/article/S0960-…
Melanie Machiels retweeted
lack of RNI benefit in low genomic score disease irrespective of whether they got chemo or not #bcsm @AndrewKellerMD @CShahMD @ErinGillespieMD @Icro_Meattini #bcsm jamanetwork.com/journals/jamao…
Melanie Machiels retweeted
Magnificent overview on when and how to use a nodal boost performed by @IBCradiation Wendy Woodward #ESTRO23 @OncoAlert #OncoAlert #radonc #breastcancer
*thank you // note to self: do not tweet when sleep deprivated
Thank for discussing preoperative #breastcancer #radiotherapy with me @HospitalULaPaz. The future is now (and female) 🔥
Melanie Machiels retweeted
PRIME II trial long-term results on @NEJM - Outstanding results reinforcing the positive impact of postoperative RT on local recurrence regardless of age (9.5% vs 0.9% 10 years). I suggest reading this brilliant commentary by @jenniferbellon2 and Alice Ho nejm.org/doi/full/10.10…
Melanie Machiels retweeted
📣Twitter takeover,tomorrow at 11:45 CET with @P_Montay_Gruel! 📍Follow us online and share your questions. @P_Montay_Gruel will be answering #FRPT2022 #FLASHradiotherapy
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