Lihan Zhang @npevolution
The Zhang lab studies (bio)chemical diversity of natural products and synthetic biology applications at Westlake University. Hangzhou, CN Joined March 2022-
Tweets49
-
Followers175
-
Following83
-
Likes77
We developed a prediction tool for the substrate amino acid of adenylation domains. Hope this can be helpful for NRPS analysis! nrpstransformer.cn
NRPStransformer, an Accurate Adenylation Domain Specificity Prediction Algorithm for Genome Mining of Nonribosomal Peptides | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
And appreciate this beautiful News&Views by Dr. Grininger for our works. nature.com/articles/s4158…
Also want to mention a recent great work by the Keasling lab about bioalcohol production by PKS! nature.com/articles/s4192…
Excited to share plug-and-play engineering of PKSs in two back-to-back papers! We demonstrate two conserved sequences in a PKS module as robust cut sites for PKS reprogramming (rdcu.be/eigV2) and show bioalcohol production by engineered PKSs (rdcu.be/eigVB).
Breakthrough in Enzyme Engineering! Researchers from Westlake University published two back-to-back papers in Nature Chemical Biology, unveiling a novel approach to enzyme engineering that could revolutionize the way we manufacture complex chemical molecules. 👉nature.com/articles/s4158… 👉nature.com/articles/s4158… #WestlakeUniversity #ResearchAtWestlake #Chemistry #Innovation #Enzyme @Nature
Out today at @ScienceMagazine - giant PKZILLA proteins spew huge polyketide marine toxins, just like #Godzilla! Witnessed by @photocyte & @VikShende at @Scripps_Ocean science.org/doi/10.1126/sc…
Excited to share our work on stereochemical prediction of cis-AT modular PKS. We found the KR motif-based prediction is affected by the module architecture and taxonomic origin of the PKS, and provided an update in stereochemical prediction. beilstein-journals.org/bjoc/articles/…
We are excited to finally publish the unprecedented biosynthetic origins of enediyne natural products: iodinated polyynes! This transformative discovery is a huge milestone for these clinical antitumor antibiotics. @Kalkreuter @guichun98 @nchembio nature.com/articles/s4158…
Move over titin... introducing PKZILLA as the largest protein in life that makes one the largest nonpolymeric compounds in biology, the marine polyether toxin prymnesin. Congrats to @photocyte & @VikShende and rest of team! biorxiv.org/content/10.110…
Interesting PKS and C domain reaction!
Our recent work published on @NatureSynthesis nature.com/articles/s4416…
Thank you Ben and the group for creating this >10k genomes (the number keeps increasing) and >100k strains database, whose strains are all available by request! npdc.rc.ufl.edu/home
Honored to have Prof. Ben Shen visit us at Westlake! NPDC is a truly wonderful resource and looking forward to exploring the strain collection. @lab_shen
Glad that our review has been selected as a VIP. Hope our bioinformatics-driven approach can be helpful in providing a clearer picture of T2PKS biosynthesis and the product molecules.
Type II Polyketide Synthases: A Bioinformatics-Driven Approach (Zhang and Xie) @npevolution onlinelibrary.wiley.com/doi/10.1002/cb…
This analysis includes more diverse T2PKSs, seemingly belonging to highly reducing T2PKSs, which we dropped in our ACIE work that focused on aromatic polyketides.
An updated catalogue of type II PKSs! (Charkoudian lab) microbiologyresearch.org/content/journa…
@CharkoudianLou @MicrobioSoc @haverfordedu @cmayemcbride In our ACIE paper we only focused on aromatic polyketide-producing T2PKSs, so we didn't include T2PKSs resembling highly reducing T2PKSs that produce polyenes. Great to see a more complete analysis!
@CharkoudianLou @MicrobioSoc @haverfordedu @cmayemcbride The 2015 PNAS paper inspired us so much and congratulations for another great work!
Wishing you a wonderful spring for the new academic year! #WestlakeSeasons #WestlakeYunguCampus
See how Yajie Wang’s synthetic biology and protein engineering team at Westlake University’s WangSynbio Lab is exploring the use of engineered enzymes and modified microbes to create a healthier, cleaner and more sustainable world. #WomenInScience #WomensHistoryMonth #HerWestlake
NASIF ALI @Nasifali1998
11 Followers 96 Following PhD student, Total synthesis of Natural products, IACS, Kolkata
Leon @lei1231898
9 Followers 149 Following
Bin GAO (Gilbert) @sugitakagi
42 Followers 460 Following /undergraduate @hkust @yangjianquan CHEM 2026/ /2025 exchanged @NUSingapore @zhu_ruyi/ /2025 summer research @UChicago @GBD_Lab/
Anton Natter Perdigue... @AntonNatter
112 Followers 532 Following PhD Student @lab_adl @UZH_ch | Synthetic Biology enjoyer
Matthew Jenner @Jenner_Lab
824 Followers 562 Following UKRI Future Leaders Fellow, University of Warwick. Natural Product Biosynthesis, Protein Mass Spectrometry, Genome Mining.
Yunfeng Luo @Yunfeng_Luo1996
0 Followers 7 Following
Akimasa Miyanaga @miyaaki1978
240 Followers 305 Following Associate Professor at UTokyo, Structural biology, Natural product biosynthesis, Polyketide synthase
YindiJiang @JiangYindi
107 Followers 219 Following Assistant Professor at the Shenzhen Institute of Synthetic Biology, CAS
enoch amevor bibah @BibahEnoch
64 Followers 383 Following MPhilChem | Aspiring PhD. student | Natural Product Chemistry | Medicinal Chemistry | Metabolomics | Chelsea FC
Runze Liu @JamesLrzz
41 Followers 248 Following Phd student in @HKU_Science, Dept of Chemistry interested in chemical biology, enzymology.
S.F. @SF_np_af
301 Followers 607 Following D1, Natural products, Biosynthesis, Engineering enzymes, Artificial enzymes, Organic chemistry
kukudedandan @wobuzdxsm
0 Followers 111 Following
Xin Liu @XinLiu315
208 Followers 308 Following Postdoc at @ColoradoStateU 🇺🇸, Ph.D. at @likat_rostock 🇩🇪
Xinqi Fan @XinqiF
59 Followers 425 Following
Gavin Williams @ChemSynthBiol
1K Followers 746 Following Chemistry Professor at NC State. Accessing the next generation of antibiotics by reprogramming the chemistry of natural product biosynthesis.
billni905 @billni905
17 Followers 733 Following
Dong-Song Tian @DongSongTian1
15 Followers 118 Following
Fang Shaocong @Carousel_Fsc
10 Followers 242 Following PhD student in biology at Westlake university MRes in Synthetic Biology at UCL 🎵🎸
Okonkwo Nwachukwu Chr... @OkonkwoNwachuk3
14 Followers 187 Following Christian, Pharmacist, Researcher #MedicinalChemistry #NaturalProducts #DrugDiscovery
Anilsth @AnilShrestha11
48 Followers 459 Following Scientist #naturalproducts # Genetic engineering.Insearchof postdoc# interested in biology of actinomycetes and bacteria# actinobacteria#
SmartMat @SmartMat2
5K Followers 8K Following A @WileyVCH's flagship #OpenAccess journal (IF = 20.4 / 2022) aiming to address the growing scientific interests in intelligent materials @smartmat.bsky.social
chun gui @guichun98
4 Followers 72 Following
Philmus Lab @PhilmusLab
2K Followers 2K Following This is the lab account for the research lab of Dr. Benjamin (BJ) Philmus (he/him). College of Pharmacy at Oregon State and focusing on natural products.
Xixihqha @yizhicaoniao
2 Followers 171 Following
Xi Zhao @XiZhao276
3 Followers 107 Following
Qingyun Dan @qingydan1991
149 Followers 354 Following Asst Prof @JohnsHopkins, Postdoc - Jay Keasling Lab @UCBerkeley, PhD - Janet Smith lab @UMich, BS @PKU1898. Synthetic Biology/Natural Products.
jianxindong1997 @jianxindong1997
18 Followers 171 Following PhD candidate at Zhejiang University, graduating in December 2024.#microbiology #SyntheticBiology #MetabolicEngineering #bioinformatics
Chinese Chemical Lett... @ChinChemLett
13K Followers 10K Following A leading chemistry journal by @ChineseChemSoc covering the whole field of chemistry. IF = 9.5 (2025). Tweets by @Zhichang_Liu on behalf of the editorial office
haixin @haixin6
11 Followers 462 Following
Lei Zhong @leizhong94
51 Followers 159 Following Postdoc @LeibnizHKI. Research on ancient natural products.
Beilstein-Institut @b... @BeilsteinInst
4K Followers 4K Following Non-profit foundation for the promotion of the chemical sciences. Publisher of Beilstein Journal of Organic Chemistry and Beilstein Journal of Nanotechnology
Wenhui Xi @wuvV9Sieb5EUpHr
47 Followers 231 Following Fudan Undergrad ｜ucsb PhD student｜ natural product enzymology structural biology｜ AI for proteins｜biochem geek
Achilonu James @pharm_achilonu
36 Followers 290 Following Pharmacist 💊 Interested in #drugdiscovery #naturalproducts
Wangqiang @wangqiang9415
11 Followers 230 Following
Jianying Han @JianyingHan
73 Followers 301 Following Institute for Molecular Bioscience; The University of Queensland; Microbiology; Natural Product Chemistry
Wenbo Ning @wen_bo123
38 Followers 209 Following Enzymology, Genome mining, Natural product🦠🧑🏻🔬｜PhD candidate in chemistry department of University of Florida
Zining Li @lizining666
103 Followers 313 Following Organic Chemistry, Biochemistry, Natural product, Enzymology
Hongjie Li @HongjieLi1
305 Followers 815 Following Zhejiang University, studying insect symbiosis, evolution, and lignocellulose biodegradation.
Qingfei Zheng @QZ_ChemSynBiol
808 Followers 2K Following Assistant Professor @ Purdue BMCMP; Chemical/Synthetic Biologist interested in Protein PTMs, Epigenetics, Microbiome, Drug Discovery; Lifelong Guinea Pig Lover
Marc Chevrette @wildtypeMC
3K Followers 2K Following Microbiome gen(om|et)ics, secondary metabolism, comp bio, antibiotic/drug disco, evolution, & hockey. he/him.
Xiaoding Jiang @XiaodingJ
157 Followers 1K Following Currently Postdoc @Hsu_Lab_UVA; Postdoc @CUHKMedicine; PhD at SYSU. Chemical proteomics & Drug discovery.
Zhongyue (John) Yang @ZhongyueY
720 Followers 487 Following AP of Chemistry @Vanderbilt. “Intelligent” protein engineer. Into cooking and poetry writing.
artemis3k @artemis3k
0 Followers 63 Following
Akifumi Sugiyama @a_sugiyama
2K Followers 605 Following Prof. Kyoto University. Rhizosphere, Specialized Metabolites 京都大学生存圏研究所教授（農学研究科応用生命科学専攻）。植物と土壌微生物の相互作用を研究しています。ダイズ、トマト、コーヒーノキを育ててます。
Gavin Williams @ChemSynthBiol
1K Followers 746 Following Chemistry Professor at NC State. Accessing the next generation of antibiotics by reprogramming the chemistry of natural product biosynthesis.
Rudolf Lab @LabRudolf
1K Followers 245 Following Natural Products, Biosynthesis, Enzymology, Genome Mining, Bioengineering
Philmus Lab @PhilmusLab
2K Followers 2K Following This is the lab account for the research lab of Dr. Benjamin (BJ) Philmus (he/him). College of Pharmacy at Oregon State and focusing on natural products.
AYA YOSHIMURA @yoshimura_aya
130 Followers 116 Following Assistant professor @ Hokkaido University Interests: Natural Products, Chemical Communications, Membrane Vesicles, Biosynthesis
Heng Chooi @YitHengChooi
975 Followers 833 Following Group leader, UWA School of Molecular Sciences... a fun-guy who loves fungi and the amazing small molecules they make
Qingfei Zheng @QZ_ChemSynBiol
808 Followers 2K Following Assistant Professor @ Purdue BMCMP; Chemical/Synthetic Biologist interested in Protein PTMs, Epigenetics, Microbiome, Drug Discovery; Lifelong Guinea Pig Lover
Zhongyue (John) Yang @ZhongyueY
720 Followers 487 Following AP of Chemistry @Vanderbilt. “Intelligent” protein engineer. Into cooking and poetry writing.
Akifumi Sugiyama @a_sugiyama
2K Followers 605 Following Prof. Kyoto University. Rhizosphere, Specialized Metabolites 京都大学生存圏研究所教授（農学研究科応用生命科学専攻）。植物と土壌微生物の相互作用を研究しています。ダイズ、トマト、コーヒーノキを育ててます。
Kounosuke OISAKI | �... @K_Oisaki
3K Followers 3K Following GroupLeader CCRI-@AIST_JP / DeputyDirector FoodMedOIL /SAB @ChemRxiv / DeputyDirector @chemstation / AssocProf @UNIV_TSUKUBA_JP / SynOrgChem, Catalysis, Protein
Eustaquio Lab @EustaquioLab
1K Followers 345 Following The Eustaquio lab aims to contribute to natural product drug discovery and development by applying genomics and biosynthetic engineering approaches.
Hang Li @HangLi13
128 Followers 162 Following Now faculty @sysu_1924, #alumnus Postdoc & PhD @UWA, Master by research @sysu_1924, China. Interested in #naturalproducts #biosynthesis. Tweets my own.
Funsho Joshua PhD @FunshoJoshua11
57 Followers 224 Following Mum, wife of a seaman and researcher. postdoctoral fellow NWU#natural products chemistry #pharmacognosy. #3D cancer cells modelling
Paul Boudreau @CatsAreFish
359 Followers 180 Following I like science and the ocean, I think natural products are cool, I am an Assistant Professor at Ole Miss School of Pharmacy. (Personal account) (He/him)
Min Lyu @Min_Lyu600
41 Followers 673 Following Deputy Director of the Office of International Affairs/Head of International Undergraduate Admissions at Westlake University, China.
Sangeet Sangroula @SangeetJourno
2K Followers 1K Following Currently @Westlake_Uni | Formerly @Tsinghua_uni @RepublicaNepal | RT ≠ endorsement
Yokoyama lab @Yokoyama_Lab
378 Followers 512 Following We study cofactor and natural product biosynthesis and enzyme mechanisms.
Duncan Kountz @14Kountz
971 Followers 1K Following Biochem and physiology of microbes | PhD with @BalskusLab | Undergrad with Joe Krzycki
Annu Chandra @Annuchandra16
272 Followers 1K Following Medicinal Chemist, Biocatalysis ,Enzyme engineering, Natural Product biosynthesis, metabolic engineering. Researcher who loves coffee and nature.
Tristan de Rond @Tristan_enzymes
661 Followers 795 Following Senior Lecturer @SCSatUoA @ScienceUoA @AucklandUni Previously: @Scripps_Ocean @Moorelabsio, @Keasling_Lab @jbei @UCB_Chemistry Loves enzymes
Anne Osbourn @AnneOsbourn1
2K Followers 721 Following Scientist and poet. My prize-winning poetry book ‘Mock Orange’ is now out
Chad Johnston @EvolvedChem
165 Followers 146 Following Assistant professor and CPRIT Scholar at the Baylor College of Medicine in Houston, starting Jan 2022. Discovery and directed evolution of natural products 🦠
TaGulder Group @biomicat
2K Followers 576 Following Organic Chemistry and Biomimetic Catalysis @ Leipzig University
Xin Zhang @kfzhangxin
2K Followers 1K Following Chemistry of Biological Aggregates; Westlake University
Jason C Kwan @kwan_lab
1K Followers 331 Following Associate Professor of Drug Discovery at the University of Wisconsin-Madison studying marine natural products, biosynthesis and metagenomics. He/him
Takeshi_Tsunoda @2nd_Tk4
239 Followers 230 Following Biosynthesis/Enzymology/Chemical Ecology/Synthetic Biology/Tokyo Tech(MSc)→U Tokyo(PhD)→Oregon State U(PD)→Hokkaido U(PJ. Asst. Prof.)→Shizuoka U(PI) , YSファン
dr. g. e. kenney is p... @kenneylab
115 Followers 69 Following microbial metalloenzymes: a tragicomedy; or, a friday night in lab. weird microbial chem fan & assistant prof @Pitt_Chemistry alum @BalskusLab @RosenzweigLab
NRPSpapers @NRPS_papers
766 Followers 0 Following Twitterbot of nonribosomal or nrps or non-ribosomal in #Pubmed created and curated by [email protected]
PKSpapers @PKS_papers
501 Followers 0 Following
Marc Chevrette @wildtypeMC
3K Followers 2K Following Microbiome gen(om|et)ics, secondary metabolism, comp bio, antibiotic/drug disco, evolution, & hockey. he/him.
Constance Bailey @CBBaileyLab
2K Followers 2K Following #SynBio and #naturalproducts. Enzymology, heterologous expression, and bioengineering. Senior Lecturer in Chemical and Synthetic Biology @SydneyChemistry.
Yuxuan Ye @YuxuanYe2
277 Followers 330 Following Assistant Professor at Westlake University; @Hysterlab postdoc; @BuchwildGroup alumni
Yang Hai @yanghaiBioChem
480 Followers 806 Following Assistant professor @UCSB_Chemistry, Structural Biochemistry, Biosynthesis and Biocatalysis
Wei li Thong @WeiliThong1
87 Followers 206 Following Biosynthesis | Synthetic Biology | Bioengineering.
Pieter Dorrestein @Pdorrestein1
7K Followers 516 Following I enjoy chemical analysis by mass spectrometry associated with microbes, microbiome, forensics, agriculture, drug discovery and metabolism.
Helfrich Lab @Helfrich_lab
921 Followers 225 Following Explorative #naturalproducts genomics at #goetheuni Frankfurt and #LOEWE_TBG. Institute for Molecular Bio Science I Tweets by lab members
Nat. Prod. Reports @NatProdReports
3K Followers 771 Following This account has been archived. Stay connected with us on https://t.co/jbOqX1hd5u, Bluesky and LinkedIn.
Yi Tang @yitang_ucla
2K Followers 181 Following Professor, UCLA. EIC, Journal of Industrial Microbiology and Biotechnology.
Bode Lab @HelgeBode_Lab
556 Followers 56 Following Run by members of the Bode Lab. Doing all things related to natural products.
ZiemertLab @ZiemertLab
1K Followers 112 Following Interested in the evolution and distribution of bacterial secondary metabolites
Alison Narayan @AlisonNarayanUM
7K Followers 1K Following Mary Sue Coleman Collegiate Professor & Director of the Program in Chemical Biology @umich working with @NarayanLab editing @ACSCentSci #biocatalysis she/her
David H. Sherman @davidhsumich
2K Followers 240 Following Hans W. Vahlteich Professor of Medicinal Chemistry, Research Professor, Life Sciences Institute; Focuses on Natural Product Sciences and Drug Discovery
O'Connor Lab @OConnor_lab
3K Followers 526 Following https://t.co/gFDz17426M A group of chemists and biochemists trying to understand how and why plants synthesize complex natural products.
Challis Group @Challis_Group
1K Followers 195 Following Research in the Challis group encompasses diverse aspects of the chemistry and biology of natural products
Craig A Townsend @CATLab20
349 Followers 50 Following advances in natural products chemistry, biology and their relation to medicine; and a laboratory to do great scienceYou might like
