Owen Hale @owenmicro
Grad student in @megbehri's lab studying the ecology, evolution, and health impacts of the human microbiome. GT alum 🐝 owenfhale.github.io Nashville, TN Joined April 2022-
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THIS WEEK: The next URIG Research Hour is this Friday, December 19 at 3:00 PM ET (2 PM CT | 12 PM PT) and will feature mentor/mentee duo Megan Behringer, PhD and Owen Hale (both at Vanderbilt University). More information: buff.ly/yVd9SrM @megbehri @owenmicro
#stachesofevolution24 Caught fan of the show @StarlCone between talks rocking some exquisite face foliage. If you're a fan of E. Coli be sure to catch his talk Monday at 1030 in 516B. Great work sir! #evolution2024 #Evol2024
Behringer lab is on our way to Montreal with an exciting lineup of talks and posters for #Evol2024! We are also recruiting Postdocs who are interested in bacterial mutation rates, experimental evolution, transcriptional regulation, and/or adaptation to resource limitation!
We're so excited for #Evol2024! Folks from the @RokasLab, @Ann_T_Tate lab, @megbehri lab, @CreanzaLab, @DeSantisLab, and @giannicast lab will all be in attendance! Don't forget to stop by our booth - hopefully our swag will make it over the border🤞😁
5 years ago I attended my 1st #ASMicrobe meeting in San Fran as a grad student poster presenter where I met my future post-doc advisor, @megbehri. Now, I’m back at #ASMicrobe in my home state and speaking in a great session! Come check out my talk! #fullcircle #growth #5yearplan
The Behringer Lab at Vanderbilt is looking to hire a research assistant! A great position for trainees interested in microbiology, evolution, & genetics while gaining experience in anaerobic cell culture, experimental evolution, & genome editing. Details at quote tweet below! ⬇️
Fwd: Job: VanderbiltU.ResearchTech.ExperimentalEvolution ift.tt/076sgUK
Hot off the presses! 📰📰 E. coli evolution in repeated 100-day Feast/Famine cycles is out in @CurrentBiology! We see high mutational order, extreme parallelism (nucleotide level!), & early mutations can ⬆️ fitness simultaneously for growth & survival! doi.org/10.1016/j.cub.…
Preprint Alert! 🚨🚨🚨 Exciting collaboration between my group, @MarcBoudvillain’s group and @bpbratton! From populations experimentally evolved to extreme feast/famine cycles, we find pH-sensing rho alleles that confer pH-dependent plasticity in transcription termination!
Evolution of pH-sensitive transcription termination during adaptation to repeated long-term starvation. biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Honored that our work was awarded the Zuckerkandl Prize by @JMolEvo. This was a terrific effort by Postdoc @sb_worthan and former undergraduate Robby McCarthy! A must read for anyone who performs lab cell culture, is interested in plasticity, or collects fitness measurements!
We're excited to announce the winner of the 2023 Zuckerkandl prize, given to the top paper in JME in the calendar year: “Case Studies in Microbial Fitness: Seemingly Subtle Changes Can Have Major Effects on Phenotypic Outcomes”, by @sb_worthan, Robert McCarthy, and @megbehri!
Good Morning! I’m excited to share our study in #mbio led by PhD candidate @StarlCone investigating 6mA evolution in E. coli! 🥳🧫🧬 Carl developed an R package (CoMMA) for differential methylation analysis of 6mA, so you can analyze differential 6mA too! journals.asm.org/doi/10.1128/mb…
August is already off to a strong start for the lab! Great presentations by postdoc @sb_worthan and Ph.D student @owenmicro at their respective GRCs! 🙌 Awesome poster by summer undergrad Briana Harness! 👏🧫🩺 Now, a ESI-MIRA NOA to start the fall semester!! 💪🥳🥳
Great day at the @VI4Research Symposium. Oven Hale (@owenmicro), a Ph. D. Student in our lab, got to share his research conducting mutation studies in Lactic Acid Bacteria.
👇Check out our most recent paper!
Excited to share our most recent paper led by postdoc @sb_worthan discussing case studies from assessing outcomes of exp. evolution. link.springer.com/article/10.100… One of most interesting findings: plastic & glass tubes are not interchangeable, E. coli acidifies LB in plastic tubes 🤯
New #preprint from our lab! Here, PhD student @StarlCone has developed an R package (CoMMA) to annotate and identify differential 6mA methylation in microbes from Nanopore data. With CoMMA he observes relaxed selection on 6mA in Exp. evolved E.coli clones without mismatch repair.
Differential adenine methylation analysis reveals increased variability in 6mA in the absence of methyl-directed mismatch repair biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Happy to share that a preprint is up for my 1st 1st-author publication! I wrote an R package for analyzing 6mA methylation in bacteria with Nanopore data. 6mA is dynamic! Less methylation around promoters, breakdown in 6mA over time w/o MMR. All the hits inside the paper!
Differential adenine methylation analysis reveals increased variability in 6mA in the absence of methyl-directed mismatch repair biorxiv.org/cgi/content/sh… #biorxiv_micrbio
New paper alert! @AReddiLab and colleagues describe differential use of exogenous and endogenous heme by M. tuberculosis in this offering. journals.asm.org/doi/pdf/10.112…
I am so proud to have the first major report of our #rUTI #metagenomics studies of the postmenopausal #urobiome published today in @CellRepMed #OpenAccess. Here's a quick summary of what we found in this @NIDDKgov and @WelchFoundation funded study. 1/7 cell.com/cell-reports-m…
So happy to finally make a thorough post about our new study with @wchoEvo, Complex Ecotype Dynamics Evolve in Response to Fluctuating Resources in @mbiojournal! (1/n) doi.org/10.1128/mbio.0…
So proud of @StarlCone! Did an amazing job at his quals today and is now a PhD candidate!!! Big day for the Behringer lab, our first grad student is now our first candidate! More good things to come! @VUGradSchool @VU_ASM @VandyBioGrad
4) We are also welcoming a new graduate student to the group, Owen Hale (@owenmicro)! Owen’s interests are metagenomics, evolution, and the microbiome. So stay tuned for great things from him!
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