Raanan Bar-Cohen @raanan

Today we're launching Intercept: a $500M philanthropic initiative to make respiratory infections, like the common cold and flu, a thing of the past. We treat respiratory infections as a minor nuisance, but that’s really not the case. Most of us will spend 5% of our lives (!) sick from these viruses, they kill 1M people a year, cost $600B annually in productivity, and periodically threaten civilization through pandemics. So, if they’re such a big problem, why haven’t we dealt with them yet? Last year we convened ~40 leading scientists, pharma R&D leaders, biotech investors, and regulatory experts to better understand that. We heard two main reasons: (1) First, it’s just technically very challenging: respiratory viruses represent hundreds of distinct, mutating strains across several families. Fortunately, recent breakthroughs make this newly possible. (2) Second is a lack of funding: broad-spectrum solutions have historically been underfunded, in part because they’re not a great fit for most philanthropic or commercial funding (and while COVID generated a burst of activity around preventing and understanding respiratory infections through an influx of new funding, that hasn't been sustained). We think that with enough focus and funding, this might be solvable. Intercept is a $500 million philanthropic initiative that will take advantage of new tools to catalyze the development and deployment of two types of products: broad-spectrum preventatives and air cleaning technologies. This problem is undoubtedly difficult. But it’s more tractable now than it’s ever been. We think we should give it our best shot. We’re enormously grateful to our anchor funders: @stripe, @AnthropicAI, @TheFluLab, @FoundationOAI and individuals from Jane Street. And, I’m very excited to be building this with @incredutility and the rest of the team.

Nan Ransohoff @nanransohoff

a day ago

interceptfund.substack.com/p/ending-respi…

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A true GOAT on all things consumer and much more. Great move by @a16z. Congrats Josh!!

Josh Elman @joshelman

2 days ago

1/ I’m thrilled to announce that I’m joining @a16z as a partner to help find and support building the next generation of great consumer companies. Let me talk a little about why.

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autonomous robot driving through the field at night. no chemicals. no pesticides. just UV light killing pathogens and pests while everyone sleeps. this is @tricrobotics. this is what chemical-free pest control looks like at scale.

I am GIVING + MATCHING $25,000 for this amazing organization (dollar for dollar; or shekel for shekel). Please consider... NIRIM🇮🇱 (we need more of this in America🇺🇸) they take very troubled youth headed for jail + turn them into elite humans via discipline, purpose & community Founded for fallen Navy SEAL Nir Krichman: 3-yr residential program, 23 community houses, night patrols & wilderness therapy. ~1000+ kids a year Match me here at any level 👇 web.causematch.com/donate/nirimis…

Every VC had a reason Vercel shouldn't exist. Guillermo Rauch heard a different reason from every investor he spoke to when building Vercel, and he kept going anyway. He joined us live at Mercury HQ in SF for Founders in Arms, and this was one of the sharpest moments in the conversation: the idea that consensus is a signal to walk away, not lean in. Full conversation with Guillermo Rauch (CEO, Vercel) on the latest Founders in Arms episode. Link in bio.

@ericwu01 Exciting!

Incredible founders can simply do incredible things. Way to go @AlexYancher. Congrats to you and the @PassportGlobal1 team.

Alex Yancher @AlexYancher

a month ago

Today marks one of the most meaningful milestones in Passport’s journey: we’ve signed an agreement to be acquired by Global-e Nine years ago, Passport started with a simple but ambitious vision: Help brands reach their global potential. Since then, we’ve built a proprietary

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This will bring AI to 42% of the web. Every model, every provider, every modality (text, image, video, audio).

Vercel Developers @vercel_dev

a month ago

The AI Gateway plugin for WordPress is here. Install it and any plugin using the WordPress AI Client can call text, image, and video models with one API key. vercel.com/changelog/verc…

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It is time for the United States Postal Service to ban junk mail. Unsolicited spam calls are already prohibited by the FCC. Emails are heavily regulated by the CAN-SPAM Act of 2003. Junk mail is the majority of mail, 100 million trees per year. Enough!

What you see vs what your Tesla is able to see

Elon Musk @elonmusk

2 months ago

The human-perceived RGB is image 1 and the Tesla AI photon count reconstruction is image 2. This is why Tesla FSD can see so well at night or through extreme glare.

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Even at 71, Paul still carries himself with the kind of energy and zest for life most people lose much earlier. I asked him what makes a great life: "God, family, friends, fun, and service." "My significance is not gonna be from being a trader. My significance is gonna be my family." "If I think about the end of my life and I look back, I'm not gonna be thinking about the 1987 crash or Bitcoin. I'm gonna be thinking about who I loved and who loved me, and what kind of times we had." "When I say legacy, I don't mean words. I mean deeds. What have you done that allowed other people to enjoy and better their station in life?"

Patrick OShaughnessy @patrick_oshag

2 months ago

My guest today is Paul Tudor Jones (@ptj_official), one of the greatest macro traders of all time. He correctly predicted the 1987 stock market crash and shorted the Japanese bubble in 1990. For over 40 years, his flagship fund has had a negative correlation to the S&P 500. 100%

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Idea for the @Tesla and really @Tesla_AI team. In Tesla cars without an FSD subscription, when a supercharger location is selected from the navigation, prompt the driver to turn on FSD (for free) about 1/2 mile before, so they can drive in and park on autopilot. Makes things safer and previews FSD to folks who don’t have it yet. I’m seeing some wild driving behavior as people manually back in reverse to some of the chargers.

Pumped to back @seapitch. When founder, product, and opportunity line up this well, it's an easy yes. Let's go!

Chris Pitchford @seapitch

2 months ago

I'm excited to share that Brev.io has raised a $3.3M pre-seed round, led by @ResoluteVC to build the AI-native layer between business goals and work. Most AI today is doing execution work in a vacuum. Without your goals, metrics, and live progress in the context

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@mitchellh @wholemars It’s amazing! but also wild that even existing owners of slightly older Teslas don’t know how far it’s come. I even noticed the difference going from a 2023 to a 2025 Juniper Model Y. That front bumper camera seems to make a huge difference - much smoother FSD.

Every.Single.Word. Just wow! A must-listen:

Shane Parrish @shaneparrish

3 months ago

My conversation with @jliemandt on why the future of education is better than you think. 0:00 The current education system 7:01 What makes Alpha School different 11:01 What are the results 23:20 Current classroom struggles 26:40 What does mastery mean? 35:37 Changing the

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BREAKING: WHOOP RAISES $575M AT $10.1B VALUATION  I am pleased to announce that we’ve raised $575M at a $10.1B valuation to accelerate our mission of unlocking human performance and healthspan globally. This round was led by Collaborative Fund with participation from 2PointZero Group, Qatar Investment Authority (QIA), Mubadala Investment Company, Abbott, Mayo Clinic, Macquarie Capital, Glade Brook, B-Flexion, IVP, Foundry, Accomplice, Affinity Partners, Promus Ventures, and Bullhound Capital alongside a group of individual investors including Cristiano Ronaldo, LeBron James, Rory McIlroy, Virgil van Dijk, and Mathieu van der Poel. This investor group and this moment reflect a powerful evolution underway for Whoop and the broader healthcare market. Whoop was born in performance - trusted by the best athletes in the world to train, recover, and compete at the highest level. That foundation remains core to who we are. You see that in the iconic athlete investors joining this round.  But it also represents our push into broader health.  In the past 12 months, WHOOP has received medical clearances, launched blood testing, and created a platform that has saved lives. Abbott and Mayo Clinic - two of the most respected and influential institutions in global healthcare - are now investors in Whoop. These are organizations that have shaped modern medicine. Their decision to partner with us is a clear validation of where our technology is headed. Healthcare systems around the world are reactive. For too long, they have waited for people to get sick, then intervene. Chronic disease is rising and costs continue to climb. At Whoop, we believe the future looks fundamentally different. We are building the most powerful, personal, preventive health platform in the world - powered by continuous biometric data, advanced analytics, and AI to help people understand their bodies and improve their health in real time. I am grateful to our team, our members, and our partners for believing in this vision. I’ve been building this company for 14 years and I’ve never been more excited for the future.

Very cool!

Cheng Lou @_chenglou

3 months ago

My dear front-end developers (and anyone who’s interested in the future of interfaces): I have crawled through depths of hell to bring you, for the foreseeable years, one of the more important foundational pieces of UI engineering (if not in implementation then certainly at

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I would like to offer to pay the salaries of TSA personnel during this funding impasse that is negatively affecting the lives of so many Americans at airports throughout the country

Vercel now powers the Notion agent platform. Not only are they a great company and product I use daily, I think they're going to be one of the big winners of the agent era. The main 'runtime' of an agent is English (natural language) documents and specs. The other ingredient is access to data and integrations. Notion is at the center of both.

Vercel @vercel

3 months ago

Vercel powers @NotionHQ's developer platform. Notion Workers use Vercel Sandbox to safely run code, giving agents the power to sync data, trigger automations, and call any API. vercel.com/blog/notion-wo…

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Incredible write up from our founder @dorna_at_gavel - those on the inside building with AI are trying to help everyone prepare for some massive changes:

Dorna at Gavel @dorna_at_gavel

4 months ago

x.com/i/article/2031…

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