Artzi Lab @ArtziLab
Biomaterial design for diagnosis and therapy to bring new technologies to patients. Cambridge, MA Joined May 2023-
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From #CancerEngineeringSummit: Natalie Artzi, PhD (@NatalieArtzi), of @harvardmed, shares how structural nanomedicine can maximize the safety and efficacy of cancer therapies, including mRNA-based treatments.
New work using cGAS #LipidNanoparticles shows how cancer cells can be used to contribute to their own elimination. Check out the work from Drs. @Alex_Cryer and @NatalieArtzi at the @wyssinstitute and @BrighamWomens: bit.ly/49terHm
💡 Researchers from the @wyssinstitute have showed they can use messenger RNA to activate the pathway and trigger the immune system to attack tumors! Check out the work from Dr. @NatalieArtzi's lab in PNAS: bit.ly/4oBNqGe Press release: bit.ly/447OtFD
Cancer's Own Machinery 'Hijacked' to Spark Anti-Tumor Response The immune-activating molecule cGAMP reacts to the presence of dsDNA in the cells’ cytoplasm, causing the #immunesystem to fight the tumor @NatalieArtzi @MassGeneralNews #melanoma #tumors hubs.li/Q03SgL_k0
Grateful to @EricTopol for highlighting the special issue on #Structural #Nanomedicine featuring our work on cGAS mRNA delivery to cancer cells to trigger immune activation. Exciting opportunities ahead! Thank you @DrMTeplensky and @CHADNANO for including us in this issue!
We keep getting better at controlling the immune system, with big implications for treating diseases 1. cGAS delivery via mRNA/nanoparticle revs up cancer immunotherapy pnas.org/doi/suppl/10.1… 2. Off-the-shelf CAR-T as good as patient-specific for lymphoma
Researchers harness tumor cells to boost antitumor immunity in preclinical cancer models, in a new @PNASNews study. Read more: massgeneralbrigham.org/en/about/newsr… pnas.org/doi/10.1073/pn… @NatalieArtzi @wyssinstitute
We keep getting better at controlling the immune system, with big implications for treating diseases 1. cGAS delivery via mRNA/nanoparticle revs up cancer immunotherapy pnas.org/doi/suppl/10.1… 2. Off-the-shelf CAR-T as good as patient-specific for lymphoma x.com/adamfeuerstein… @adamfeuerstein 3. Structural immunotherapy pnas.org/doi/10.1073/pn…
Caribou Biosciences $CRBU said Monday that its off-the-shelf CAR-T therapy induced complete and durable remissions in patients with advanced B-cell lymphoma. The study results, while preliminary, are comparable to benchmarks set by currently approved, patient-specific CAR-T
Cancer Cell Enzyme Activates Antitumor Immune Pathway Tumors were eradicated in 30% of mice receiving cGAS #LNPs injected into the tumor, in combination with immune checkpoint blockade @NatalieArtzi @MIT_IMES #immuneresponse #cancercells #cancertherapy hubs.li/Q03RzhD20
Restoration of cGAS in cancer cells promotes antitumor immunity via transfer of cancer cell-generated cGAMP pnas.org/doi/10.1073/pn… @NatalieArtzi @MIT
Precision medicine meets biomaterials - @harvardmed ’s Prof. @NatalieArtzi joins us to share cutting-edge insights. #ConwayFest25 #Biotech
I’m delighted to share our new perspective article, “33 Unresolved Questions in Nanoscience and Nanotechnology,” just published in ACS Nano. This work charts a bold vision for the future of nanoscience and nanotechnology. pubs.acs.org/doi/10.1021/ac…
Congratulations to @NatalieArtzi for being appointed Associate Institute Director of the @wyssinstitute at @Harvard! wyss.harvard.edu/news/wyss-inst…
On my way to UCSD, I spotted myself on the screens at Logan Airport—so happy and proud to represent Mass General Brigham! @MGBResearchNews
Structure is the secret. In today’s ACS Nano perspective, Chad Mirkin and a team of scientific leaders explain how carefully engineered nanomedicines could make treatments safer, smarter, and more effective. pubs.acs.org/doi/10.1021/ac…
In a new commentary, researchers from the @BrighamWomens @wyssinstitute discuss the emerging era of structural nanomedicine. Read more: nature.com/articles/s4422… @NatalieArtzi
"The emerging era of structural nanomedicine" A new perspective from @CHADNANO, Milan Mrksich, and @NatalieArtzi (@Harvard) reveals that the structure of #nanomedicines is key to their therapeutic potency and regulatory success—not just their components. nature.com/articles/s4422…
The emerging era of structural nanomedicine bit.ly/4cO80hz
When women spend 25% more time in poor health than men, the news that the government is slashing funding to the pivotal Women's Health Initiative highlights the importance of supporting & talking about women's health. Read more from @statnews: bit.ly/448WOtF
A new perspective from Chad Mirkin (@CHADNANO), Milan Mrksich, and Natalie Artzi (@NatalieArtzi) charts a bold future for precision nanomedicine. Out now in Nature Reviews Bioengineering: nature.com/articles/s4422…
Our first panel session, Bold Science from ARPA-H, discussed how ARPA-H funding is pushing the limits of healthcare tech by embracing high-risk, high-reward research💥Thank you to panelists Natalie Artzi, R. Todd Constable, Clark Hung, and Mark Skylar-Scott 🙌 #BMEII2025
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