Gene Tools support @GeneTools
Gene Tools, LLC manufactures Morpholino antisense oligos for binding RNA and blocking processes. gene-tools.com Philomath, Oregon Joined October 2011-
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Spermine oxidase promotes oxidative stress during islet inflammation doi.org/10.1016/j.jbc.…
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Architecture of distal tips of motile cilia is shaped by the pseudoenzyme Jhc1 in non-mammalian vertebrates doi.org/10.1016/j.celr…
Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody–Oligonucleotide Conjugates with High Drug-to-Antibody Ratios doi.org/10.1021/acs.jm…
Astrocyte activation mediates UV filter PBSA-induced impairment of neurogenesis via the rxrga/tsp-1 axis during a sensitive developmental window in early life stage zebrafish doi.org/10.1016/j.cbi.…
Structural Optimization of Guanidinium-Linked Morpholino Phosphorodiamidate Morpholino Oligonucleotide Chimeras to Improve In Vitro Antisense Efficacy doi.org/10.1021/acs.bi…
A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts doi.org/10.1111/gtc.70…
Splice-altering TP53 missense mutations as drivers of dysfunction and targets for RNA-based therapy link.springer.com/article/10.118…
Targeted α-synuclein mRNA degradation by PMO-based RNA-degrading chimeras doi.org/10.1073/pnas.2…
Oxidized PDI promotes thrombus formation in oxidative stress doi.org/10.1182/blood.…
SIX1 branchio-oto-renal syndrome variants have different effects on embryonic craniofacial gene expression and cartilage formation doi.org/10.1242/dev.20…
LINC00607 facilitates endothelial VEGF-A receptor FLT1 splicing doi.org/10.1016/j.ymth…
ATP6V1B2 Regulating Autophagy Flux To Affect Abnormal Auditory Development link.springer.com/article/10.100…
A Splice-Site Variant in ACY1 Associated with Congenital Hearing Loss: Clinical, Biochemical, and Zebrafish Functional Evidence link.springer.com/article/10.100…
The Versatile Applications of Antisense Oligonucleotides in Modern Medicine mdpi.com/1422-0067/27/1…
Kinetic and thermodynamic properties of phosphorothioate and phosphorodiamidate morpholino oligonucleotides binding to target RNA doi.org/10.1093/jb/mva…
A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy link.springer.com/article/10.100…
The ezrin Gene Regulates Early Cardiac Morphogenesis and Contractile Function in Zebrafish Through the Coordinated Regulation of Apoptosis, Calcium Homeostasis, and the MAPK Signaling Pathway doi.org/10.3390/cells1…
An aquaglyceroporin governs cellular water and CO2 conductance relevant for vesicular mineral formation in a marine calcifier doi.org/10.1073/pnas.2…
ZL006 Treatment Reduces Inflammation, Oxidative Stress, and Brain Aβ1–42 Accumulation and Rescues the Loss of PSD95 Synaptic Marker in Familial Alzheimer’s Disease-Associated psen1-Deficient Zebrafish Model doi.org/10.3390/ijms27…
Gene body methylation suppresses intragenic transcription and permits epigenetic inheritance in a cnidarian nature.com/articles/s4155…
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