Jonathan Silverberg, MD, PhD, MPH @JonathanMd
Dr. Silverberg is a Professor of Dermatology at the George Washington University School of Medicine and Health Sciences Joined January 2019-
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Join the Revolution next month in Nashville. You can register for FREE using the code: Silverberg at checkout #PER #eczema #dermatology
Join me in Music City June 6–7 for the Revolutionizing #AtopicDermatitis conference! Immerse in Nashville’s unique charm. Earn CME over two days of cutting-edge derm education. Use Silverberg at checkout for free registration bit.ly/4iN3X7a #RAD2025 #gotoper
The Revolutionizing Atopic Dermatitis Conference in in Nashville, TN on June 6–7 this year! Join me and leading experts for two days of learning, networking, and AD insights. Use my code Silverberg for free registration! bit.ly/4iN3X7a #RAD2025 #AtopicDermatitis #gotoper
Thrilled to share that Dr. Chovatiya will be joining me at Revolutionizing Atopic Dermatitis (RAD) on June 6-7 in Nashville, TN! Use my code Silverberg for free registration and save your spot now: bit.ly/41D2vwU #RAD #AtopicDermatitis #gotoper
Join me at Revolutionizing Atopic Dermatitis (RAD) on June 6-7 in Nashville, TN! We will be discussing groundbreaking concepts in AD—where medicine meets Nashville’s rhythm. Use my code Silverberg for free registration: bit.ly/41D2vwU #RAD #AtopicDermatitis #gotoper
You’re invited to the December virtual update on Revolutionizing Atopic Dermatitis! Get ready for CME/CE with practical patient-centered conversations and presentations on late-breaking research. Join us on December 8: bit.ly/3Z1YMaW @JonathanMd , @RajMDPhD
Check out this study of the validity of ICD10 codes for identifying #atopicdermatitis in health services research. You can learn more about these results at the @RevAtopicDerm conference on December 11th. rdcu.be/cZv7g #eczema #dermtwitter #allergy #dermatology
New Directions in Atopic Dermatitis Management: Harnessing the Power of Social Learning to Improve Patient Outcomes medicallogix.gathered.com/invitation?ref…
Stay tuned for more programs.
33) And that's it! You just earned 0.5h CE/#CME just by following this 🧵. Accredited education on Twitter! What a concept! I am @JonathanMd inviting you to FOLLOW @derm_ce for more #tweetorials in #dermatology from expert authors. #dermtwitter #FOAMed @derminterest @DermNPPA
It is an exciting time in #dermatology.
31) There is growing evidence that JAK inhibitors are efficacious in #atopic_dermatitis, #alopecia_areata, #psoriasis, & #vitiligo. Additional evidence suggests that JAK inhibition may be broadly useful in dermatology, with early reports of efficacy in several other conditions.
29) Studies in Japanese adults with #AD of #topical #delgocitinib 0.5% ointment have been promising. See 🔓jaad.org/article/S0190-…
25b) Significant itch reductions versus vehicle were reported within 12 hours of first application of 1.5% RUX (P < .05). Application site reactions were infrequent (<1%) and lower with RUX versus vehicle; none were clinically significant.
24a) Indeed, there are 2⃣: Topical #Ruxolitinib Evaluation in #Atopic_Dermatitis Study 1 (NCT03745638) & Study 2 (NCT03745651) #TRuE_AD enrolled patients aged ≥12 yrs with AD for ≥2 yrs, an Investigator's Global Assessment score of 2/3, and 3%-20% affected body surface area.
Welcome back everyone! If you missed yesterday's posts, all you have to do is scroll up. Enjoy!
21) Welcome back! I am @JonathanMd and we are all about #topical #JAK inhibitors for atopic dermatitis #AD on your ONLY source for CE/#CME #accredited #tweetorials in #dermatology. Your link to your 🆓credit is at the end of this 🧵! 👏@eczemasociety @nationaleczema
See you back here tomorrow
20) Show us what you learned by marking your best answer. Correct responses--and your link to 🆓CE/#CME to follow when we see you here tomorrow. 👍to @DrCandriceHeath @nationaleczema @DrJanPeds @aaron_drucker @JosephMerolaMD @paller_lab @Dr_BaderAlOmair @DrJoelGelfand
See how much you know about JAK-inhibition in AD
19) Follow-on Ph 3 studies yielded similar results. We'll address those TOMORROW and also talk about potential emerging topical #JAK inhibitors still to come. Meanwhile, which JAK receptor/s does #ruxolitinib inhibit?
10a) Thus #JAK inhibition can block the effects of multiple cytokines that are major players in #AD pathophysiology & ⬇️symptomatology. As per previous expert tweetorials from @DrStevenTChen @itchdoctor @Aller_MD (still available for CE/#CME credit at academiccme.com/dermatology-tw…)...
9) The #JAK-#STAT signaling pathway mediates effects of several key #cytokines on immune cells, keratinocytes, and peripheral sensory neurons that lead to inflammation and itch, including IL-4, IL-5, IL-13, IL31, IL-22, and TSLP See pubmed.ncbi.nlm.nih.gov/34437922/.
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