Seth Cheetham @SethCheetham
Cheetham Lab @AIBNatUQ |Director @NationalBiolog2 | ARC Future Fellow | #mRNA drug discovery | https://t.co/UCsRaX8MG2 researchers.uq.edu.au/researcher/196… Brisbane, Queensland Joined July 2017-
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To accelerate #mRNA vaccine and therapy research, I'm excited to share our end-to-end protocol for #mRNA design, synthesis and encapsulation in @NatureProtocols. Protocol development by @LauraJLeighton, Natasha Chaudhary and Tim Mercer. @BASEmRNA nature.com/articles/s4159…
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A huge milestone for personalised #mRNA therapeutics for inherited disease! A baby with an ultra-rare mitochondrial disease was treated at UPenn with an mRNA-encoded gene-corrector. The mRNA was made to treat a single individual in just 7 months! nejm.org/doi/full/10.10…
The technology is programmable and works with other targeting arms including anti-PSMA (highly expressed on prostate cancer cells) bispecifics.
Systemic mRNA-LNP delivery beyond the liver? Check out our recent paper demonstrating cell-specific mRNA-LNP delivery using PEG- and target cell-specific antibodies. This approach can customised to any target cell-type with off-the-shelf mRNA-LNPs. 1/ sciencedirect.com/science/articl…
Exited to share our latest preprint! mRNA-LNPs are efficiently delivered to healthy livers, but what about liver tumours? Our postdoc Laura Leighton found liver tumours efficiently take up mRNA, enabling next generation mRNA-LNP cancer therapeutics. biorxiv.org/content/10.110…
Interested in undertaking a #PhD in the transformative field of #mRNA cancer vaccines? I have an earmarked PhD #scholarship available for an outstanding domestic student to join our team at @UQ_News and @BASEmRNA . If this sounds like you, get in touch. study.uq.edu.au/study-options/…
Seth Cheetham retweeted
Opportunity for a bioinformatician to join the lab @PeterMacRes to help us identify new Immunotherapies. Please reach out for further details. Ad is for a post doc but research assistants considered. 💻 🧬. See link below.
Wow this is super cool! Single-cell resolution imaging of #mRNA-LNP biodistribution in cleared mouse bodies. nature.com/articles/s4158…
Exciting news! @BASEmRNA and Vaxxas have been awarded the $2M USD Biomedical Advanced Research and Development Authority (BARDA) Patch Forward Concept Stage Prize to develop thermostable needle-free mRNA vaccines! @AIBNatUQ uq.edu.au/news/article/2…
Awesome work from @MJMitchell_Lab at UPenn in @Nature identifies novel LNPs that can deliver #mRNA to the placenta. Using the placenta-targeting LNPs to deliver VEGF mRNA improves pre-eclampsia in animal models. nature.com/articles/s4158…
Earlier this year I had the opportunity to present a TEDx talk on the transformative potential of personalised #mRNA vaccines for cancer. The recording is out now: youtube.com/watch?v=BnSOgJ… @AIBNatUQ @BASEmRNA @UQ_News
@BASEmRNA Work led by Helen Gunter @Mercerlab1, @AIBNatUQ @TRI_info @UQ_News Try it out here: basefacility.org.au/software/
There are more ways to design an mRNA than atoms in the universe, so how do you choose the best one? Our new @BASEmRNA software, mRNArchitect enables you to tune expression, stability, reactogenicity and synthesisability to design more potent #mRNA drugs biorxiv.org/content/10.110…
@andreabrandlab Congratulations all. Very cool to see a resolution to this longstanding mystery.
BASE mRNA Facility @BASEmRNA
1K Followers 1K Following A federally-funded RNA Manufacture and Research Hub located at @AIBNatUQ | Tweets about the all latest mRNA news | Retweets are not endorsements.
Mark Dawson @MAF_Dawson
5K Followers 969 Following Fully support🇺🇦 Haematologist & Scientist @PeterMacCC and @UMCCR Group Leader @TheDawsonLab - views expressed are my own
UQ News @UQ_News
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Geoff Faulkner @Faulkner_Lab
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Translational Researc... @TRI_info
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Anthony Beckhouse @AntoBeck
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Mark Dawson @MAF_Dawson
5K Followers 969 Following Fully support🇺🇦 Haematologist & Scientist @PeterMacCC and @UMCCR Group Leader @TheDawsonLab - views expressed are my own
UQ News @UQ_News
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Institute for Molecul... @IMBatUQ
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1K Followers 753 Following Head of Infection, Immunity and Metabolism. Professor at Univ of Queensland. Global health matters, #TB #diabetes #viral infections. Views my own.
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AIBN Research @AIBNatUQ
3K Followers 407 Following This account has been archived. Visit https://t.co/PjCeuoqhM9 for the latest updates.
Translational Researc... @TRI_info
5K Followers 1K Following This account is no longer active. Posts are retained as a record. For updates, please follow us on LinkedIn, Instagram & Facebook. https://t.co/WFxZ3vvmEy
Anthony Beckhouse @AntoBeck
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