Spike Tree Lab @SpikeTreeLab

Bioinformatics, genomics and autism research from a parent's perspective. Joined May 2026

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Spike Tree Lab @SpikeTreeLab

2 months ago

Checking out HISAT-genotyping for DNA profiling (forensic markers). Got 12 out of 13 markers matching for NA12878 and for personal DNA. Here is pipeline github.com/SpikeTreeLab/h… #DNA #Bioinformatics #Genomics

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Spike Tree Lab @SpikeTreeLab

2 months ago

Tested with whole genome sequencing data from @SequencingCom and a forensic DNA profile from @AlphaBioLabs. 17 of 22 CE/CODIS STR markers matched, demonstrating that the pipeline can detect agreement between WGS data and a reference forensic profile.

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Spike Tree Lab @SpikeTreeLab

2 months ago

🧬 Just published an open-source pipeline to verify whether a whole genome sequence matches a known forensic DNA profile (CE/CODIS STR markers). Useful for confirming sample identity before downstream analysis. github.com/SpikeTreeLab/f… #Bioinformatics #Genomics #OpenSource

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