Stanford Snyder Lab @TheSnyderLab

Check out @SnyderShot's chat @ The Rose Woman Podcast: You as a #Data Stream the New World of #Multiomics and Optimizing #Healthspan christinemariemason.com/podcast/you-as… The Rose Woman Podcast

Featured on the cover of Genome Research journal, our new study reveals that ULI-HiFi improves the characterization of genetic variants in dark regions of genomes. lnkd.in/gUBABTh2 @SnyderShot @grahamserwin Katherine Wang @Baylor @StanfordMed @Stanford

Should Everyone Be Taking GLP-1s? (link at the end) 1/7) Over the past few years, we’ve witnessed a massive societal shift in opinion on GLP-1s: from supreme skepticism to the provocative question: “Should almost everyone be taking a GLP-1?” Honestly, my own perspective leapfrogged from: “These are overhyped” to “Maybe they’re not being hyped enough” Or more precisely:  The benefits people ARE hyping may only be the tip of the iceberg. These aren’t just weight-loss drugs. Today’s 6,000-word deep-dive (link at the end) is intended to be your one-stop shop for understanding GLP-1s. So, let’s start with a few fascinating facts you may not have heard.

What if your smartwatch could tell you were sick before your first symptom? npr.org/2026/07/10/nx-… Genetics professor Michael Snyder: wearables are ushering in an era of highly-personalized, precision medicine. @SnyderShot #2 of TED Radio Hour "Tracking what your body needs"

Actually, here is my TED NPR interview with Mannish. It was a ton of fun! npr.org/2026/07/10/nx-… Don't forget to visit MySuppleHub for info on supplements. Getting lots of great comments! mysupplehub.org/#/

We launched a new website to a) Provide information about supplements b) find out what people are using and c) share their experiences. Check it out: mysupplehub.org/#/

go.ted.com/michaelsnyder ✨ The TED Talk of the year! with @SnyderShot Michael Snyder, PhD: "Why I’m obsessed with health wearables (and you should be too)" Genome researcher Michael Snyder believes health wearables can transform medicine, shifting from reactive to predictive.

Behind our every breakthrough to improve outcomes for cancer patients is our incredible team. Continuing our 2026 #EmployeeSpotlight series is Chris Rife, Senior Software Engineer. Chris’ role focused on the development and maintenance of our robust lab systems.👇 “Software engineering is as much about communication as it is coding. There are many subtle details around the various processes and data flows, and we need a comprehensive understanding of those things to successfully translate them into software.” #LifeAtPersonalis #TeamAppreciation #CompanyCulture #HealthcareInnovation

Folks, Do not forget to check out this supplement web site. We want your feedback: mysupplehub.org/#/

Snyder Lab Publishes Global Multiomics Study Revealing How Geography and Ethnicity Shape Human Biology sciencedirect.com/science/articl… International research team completes one of the most comprehensive molecular studies of human diversity cell.com/cell/fulltext/… @SnyderShot

Our consortium paper on deep profiling of individuals of different ethnicities located across continents just came out. I HPP initiative involving many different labs from aorund the world and an amazing open access resource. Full of cool results. cell.com/cell/fulltext/…

Watch Yesterday's GenomeWeb Webinar : Disrupting Healthcare Using Deep Data, Remote Monitoring, and AI - event.on24.com/wcc/r/5286131/… @SnyderShot @GenomeWeb @DailyScan @DailyNewsGW @GenomeWeb🧬🧬🧬

We just launched MySuppleHub, a database for supplements mysupplehub.org Search for any supplement question. We also want to hear your experience. Please fill out the survey--we can let you know what others think.

Excited to share that our team (Decode ALS) has been awarded the Longitude prize to fight ALS using AI. Our lab will be responsible for designing AI to discover new drug targets. Stay tuned for more cool stuffs from us! @Yale @YaleMed @YaleBIDS

Longitude Prize on ALS @longitude_prize

3 months ago

We're proud to announce the 20 Discovery Award winners have been selected for the #LongitudePrizeOnALS – each receiving £100k to use AI to identify new drug targets for the disease. Find out more 👉 als.longitudeprize.org @Challenge_Works @mndassoc

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@patientled and RTHM Clinic recently released the Long COVID Treatment Guide to support more informed conversations between patients and their clinicians. The guide covers over 30 different interventions. Today, we’re highlighting maraviroc, a medication that has shown promise for people with Long COVID, especially those experiencing cognitive impairment, fatigue, post-exertional malaise, and other inflammation-related symptoms. Maraviroc may help by targeting immune dysregulation through the monocytic-endothelial-platelet axis, a pathway believed to play a role in Long COVID symptoms. In research, maraviroc paired with pravastatin was associated with improvements in neurological, autonomic, respiratory, cardiac, and fatigue symptoms, along with vascular markers. A patient survey found 64% of people reported a slight to significant improvement with maraviroc. In the Harvard/Stanford TREATME study, 42% of individuals with Long COVID who tried maraviroc reported moderate to much better improvement in symptoms. A clinical trial is also underway at Mount Sinai to further evaluate its potential in Long COVID. As with all treatments in the guide, maraviroc is prescribed off-label and should be discussed with a clinician to determine whether it is appropriate for an individual case. The treatment guide is an evidence-based resource hub designed to make research easier to understand so patients and clinicians can make informed decisions together. Download the guide here: rthm.com/treatmentguide

Comprehensive combined #germlinetesting & #somatictesting in #patients w/ 33 types of #cancer found: 100% of #patients positive for an actionable #germline variant (#PGx) 42% were positive for an actionable #somatic variant matched to a #precisiontherapy 8% were positive for a pathogenic #germline cancer predisposition variant (PGV) in the same cohort (cell.com/cell/fulltext/…) #PGx, one more reason #Universal combined #germline & #somatic #sequencing in #oncology should be implemented to enhance #therapeutic precision, minimize #adverse effects, & inform #individualized treatment decisions. c/w ascopubs.org/doi/10.1200/PO… @EdEsplin et al. @JCOPO_ASCO ascopubs.org/doi/10.1200/JC… @VivekSubbiah @Dr_R_Kurzrock @JCO_ASCO #access #reducedisparities #precisionmedicine #clinicaltrials #precisionprevention ascopubs.org/doi/10.1200/PO… #VaiPathak et al. @JCOPO_ASCO @ASCO

Big news: Our Virtual Embryo project has been selected as a Laude Institute Moonshots Seed Grant winner — chosen from 125 proposals evaluated by 600+ leading researchers. I’m deeply honored to be recognized alongside a remarkable community that includes Fields Medalists like Terence Tao, Nobel laureates like Michael Kremer, Turing Award winners like Raj Reddy, and creators of transformative tools such as Jupyter Notebook. We are now building (1) the largest time-resolved organism-level 3D perturbation atlas of mouse embryogenesis; (2) what could become the first digital twin of mammalian embryogenesis — a predictive model of development designed to uncover the mechanisms of congenital disease and ultimately help ensure that every newborn has the healthiest possible start in life. If this vision excites you, come build with us — alongside Emily Fox, James Zou (@james_y_zou), and Marinka Zitnik (@marinkazitnik). Thank you to @LaudeInstitute for believing in this vision. We also welcome industrial and philanthropic partners who want to help shape the future of developmental biology and human health.

The Quest to Predict Disease Before Symptoms Strike Could the signs of a heart attack months away be hiding in your watch? @SnyderShot reveals in @Medscape Learn more: medscape.com/viewarticle/in…

"Our #Multiomics integration study...underscores the potential of #Multiomics profiling to improve risk estimation & disease stratification in #pediatric B-cell precursor #acute #lymphoblastic #leukemia (BCP-ALL)." cit. "#Multiomic analysis of #familialadenomatouspolyposis reveals molecular pathways associated with #early #tumorigenesis" nature.com/articles/s4301… @EdEsplin et al. @NatureCancer #genetic #genomic #transcriptomic #proteomic #metabolomic #lipidomic #precancer #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention nature.com/articles/s4385… #OlgaKrali et al. @CommsMedicine

🔥 Last Day to Register! AI Longevity Course - How We Age Enrollment Open to Everyone: genetics4.eventbrite.com - Human Organ Health in Focus - Unique Opportunity Taught by Stanford Genetics Professors - Begins Thurs, Apr 2 at 4:30 pm PST @SnyderShot