David S. Wishart @WishartLab

A promising step toward more accessible metabolic monitoring 🧪🌍 A recent study describes a rapid, low-cost colorimetric multimetabolite assay for the quantitative measurement of urinary keto acids associated with phenylketonuria (PKU) and maple syrup urine disease (MSUD). Unlike many current approaches that are either qualitative or require specialized laboratory equipment, this method was designed to support simple, at-home monitoring with quantitative readouts in just minutes. This kind of innovation has the potential to make a meaningful difference for individuals and families managing inborn errors of metabolism, particularly in settings where access to advanced metabolic clinics is limited. Expanding reliable, user-friendly tools for screening, detection, and dietary monitoring is an important step toward more equitable and proactive metabolic care. pubmed.ncbi.nlm.nih.gov/41767879/ #Metabolomics #PKU #MSUD #InbornErrorsOfMetabolism #Biomarkers #PrecisionMedicine #GlobalHealth #Diagnostics #TranslationalResearch

Because Parkinson’s biology can evolve long before clinical diagnosis, studies like this are essential for advancing early detection, risk stratification, and precision health in neurodegenerative disease. Congratulations to the authors on this valuable contribution. pubmed.ncbi.nlm.nih.gov/41565969/

🚨 New in #ParkinsonsResearch: A 5-metabolite blood panel + key non-motor features can distinguish early, intermediate & progressive PD. Minimal sample, brief interview, big potential! 👏 Congrats to the authors! #Biomarkers #NeuroScience Read the article here: nature.com/articles/s4159…

Join The Metabolomics Innovation Centre (TMIC) in a one-day symposium on the latest advancements in metabolomics, featuring 10 presentations, poster sessions and valuable networking opportunities. Don’t miss this opportunity to connect, collaborate, and explore cutting-edge research with the metabolomics community. Date: February 17, 2026 Location: Centennial Centre for Interdisciplinary Science (1-440) & PCL Lounge, University of Alberta Learn more: app.groupize.com/e/alberta-meta…

I’m deeply honoured to receive the 2025 University Cup, the University of Alberta’s highest award for excellence in teaching, learning, and research. 🎥 Watch this video to learn more about my work and the incredible community that makes it all possible: youtu.be/dPYfaWeyank?si…

🚨 New Publication Alert! 🚨We’ve comprehensively profiled NIST SRM 1950 using 4 powerful platforms and 8 assays, identifying 1058 metabolites! Check out our online database, SRM1950-DB, for the most complete quantitative characterization of SRM 1950 to date!🔗 Learn more here: pubs.acs.org/doi/10.1021/ac… #Metabolomics #Research #SRM1950 #Science #DataScience #MassSpectrometry #Metabolites

🔬 We’re Now on BlueSky! 🔬 Follow us for the latest updates, research findings, and insights in the world of metabolite profiling and more. Let’s connect, collaborate, and grow the metabolomics community together! 👉bsky.app/profile/wishar…

🚀 Unlock the Power of Quantitative Metabolomics with the GIGA KIT! 🔬 The GIGA KIT is your all-in-one solution for high-throughput metabolite analysis, quantifying up to 1780 metabolitesand 400 sums & ratios across 39 chemical families—all from just 40 μL of biofluid! 💡 Key Highlights: ✅ Tailored for serum/plasma, urine, and fecal extracts (urine & fecal version coming soon) ✅ 96 well-plate compatible for streamlined workflows ✅ Fast Prep Time – 3 hours for 96 samples ✅ LC-AutoFit Software for automated LC-MS data processing, compatible with major instruments Perfect for researchers aiming for precision, efficiency, and depth in metabolomic studies. See the brochure here: acrobat.adobe.com/id/urn:aaid:sc… 📞 +1 (780) 492-4005 | 📧 [email protected] | 🌐 metabolomix.ca #GIGAKIT #Metabolomics #LCMS #Biotech #ResearchTools #Innovation

New breakthrough in colorectal cancer (CRC) diagnostics. We've developed a simple, fast, and affordable colorimetric assay to detect N1, N12-diacetylspermine (DAS) in urine, a key biomarker for CRC. By using recombinant diacetylspermine oxidase (rDAS Ox) and a unique two-column method to concentrate DAS, we can now detect levels as low as <1 μM—a game changer for low-resource settings! This is the first reported enzymatic assay to accurately quantify DAS in urine, offering a quicker, cheaper alternative to traditional methods. Learn more here: sciencedirect.com/.../pii/S00032…... #colorectalcancer #CRC #CancerBreakthrough #cancerdiagnostics #Biomarkers #dasdetection #urinetest #colorimetricassay #AffordableDiagnostics #MedicalInnovation #biotechnology #lowresourcehealthcare #gamechanger #rDASOx #enzymaticassay #healthtech #fastdiagnostics #GlobalHealth #cancerresearch #urinebiomarker #ScientificDiscovery #MedicalAdvancements

I’m truly grateful for the opportunity to be the first guest featured in MetaboNews’ new Perspectives section! This exciting initiative will offer a unique look into the evolution of metabolomics, as well as its future directions, through interviews with key figures in the field. In my interview, I reflect on the growth of metabolomics, share insights on where it’s headed, and discuss the role of technology, like AI, in shaping its future. facebook.com/TMICCanada/pos…

🌟Did you know our MEGA Kit can measure over 700 metabolites in fecal samples?🌟 Unlock key insights into gut health with our advanced MEGA Kit for fecal sample analysis. 💡 Why Choose MEGA Kit? Powerful Analysis: Quantifies 726 metabolites across 21 chemical families. Minimal Input: Just 100 mg of fecal material needed for comprehensive results. Wide Applications: From gut disorders (IBS, IBD) to gut-brain axis research (ASD, Parkinson’s). 🚀 Seamless Workflow: Fully compatible with 96-well plates for efficient, accurate results. 💻 LC-AutoFit: Easily analyze data with our tailored tool for quick, actionable insights. 📞 Learn More Here: acrobat.adobe.com/id/urn:aaid:sc… Contact Us: metabolomix.ca or email [email protected]. #GutHealth #Metabolomics #Microbiome #BiomedicalResearch #FecalMetabol

Unlocking the Power of Homoarginine (hArg) Homoarginine (hArg) is a lesser-known metabolite with big potential! From protecting cardiovascular health to possibly serving as a biomarker for diseases, hArg plays a crucial role in our body. In this article, you can find: -How low hArg levels are linked to heart disease and higher mortality risk. -Its potential as a diagnostic tool for immune, liver, and pregnancy complications. More research is needed, but hArg may soon be a game-changer in healthcare! Learn more here: onlinelibrary.wiley.com/doi/10.1111/ap… #HealthScience #Metabolomics #CardiovascularHealth #PregnancyResearch #AminoAcids #MedicalResearch #Wellness

As we reflect on an incredible year, we’re proud of what we’ve achieved at the Metabolomics Innovation Center. Despite challenges, we continued pushing the boundaries of metabolomics research and technology. Next year promises even more success, developments, and breakthroughs. We’re excited to continue advancing science, empowering researchers, and exploring new frontiers in metabolomics! Here’s to a year full of discovery and collaboration! 🚀 #Metabolomics #Innovation #Research #Science2025 #TMIC

🌐 Introducing NP-MRD: A cloud-based, FAIR database for managing & analyzing NMR data from natural product research! 🚀 Key features: ✅ Raw & processed data support ✅ Fast & easy data submission (<5 min/spectrum) ✅ Advanced validation & DFT calculations ✅ High data integrity Start using NP-MRD today: pubmed.ncbi.nlm.nih.gov/39590858/ #NP_MRD #NMRData #NaturalProducts #ResearchTools #DataScience #Metabolomics

This talk by Navdeep Singh offers a comprehensive overview of fine-tuning generative AI models. It covers essential tools and methodologies, the mechanics of weight updates, and various fine-tuning strategies. Listeners will gain insights into practical use cases, evaluation methods, and common challenges, providing a thorough understanding to enhance model performance effectively. youtu.be/qfJvXxE1zZY?si…

🚀 MarkerDB 2.0 is here! 🚀 We're excited to roll out major updates to MarkerDB, featuring: 🔬 Thousands of new biomarkers 🧬 Expanded categories & types 🔍 Improved search & filtering 📊 Enhanced tools for exploring biomarker panels Explore more here: 👉academic.oup.com/nar/advance-ar… #Biomarkers #Genomics #MedicalResearch #MarkerDB #HealthcareInnovation #OpenDat

Incredible to see the groundbreaking work in metabolomics, especially from our team. Well done, everyone! #MetabolomicsDay2024 #Innovation

Wishart Node of The Metabolomics Innovation Centre @WishartNode

2 years ago

🌟 Thrilled to participate in Metabolomics Day 2024! Our team showcased exciting new research through posters and Dr. David Wishart’s keynote on "Metabolomics, Metabolites, and Medicine." Huge thanks to everyone who attended! #MetabolomicsDay2024 #Innovation #Research

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