Subramaniam Lab @arvind_rasi
We study mRNA translation rasilab.github.io Seattle Joined December 2015-
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The era of coding agents is here. How do we approach this as scientists? Wednesday Dec 10th at 9am PT I'll livestream an interactive demo of what I have learned (matsen.group/agentic.html) about how to leverage agentic coding to do rigorous science. youtube.com/watch?v=Rbhs7C…
The Mahan postdoctoral fellowship offers 21 months of support to develop your own research with Fred Hutch computational biology faculty-- lots of excellent labs to choose from! Apply: apply.interfolio.com/172697 Faculty: fredhutch.org/en/research/di…
We are hiring a postdoc to work on ribosome quality control and ribosome-mediated stress signaling. Start date is expected to be Fall- Winter 2025. More information can be found here: rnasociety.org/fully-funded-p…
Biorxiv preprint: biorxiv.org/content/10.110…
Excited to share the work of postdoc Rachael Bakker in collaboration with @C_P_Lapointe lab! We show that RNA base editors can be repurposed for deep mutational scanning of RNA-RBP interactions at scale both in vitro and in vivo.
Our latest preprint, regarding endogenous RQC substrates, is online! This is a wonderful collaboration with Taku Ito lab from RIKEN BDR!
Sense codon-misassociated eRF1 elicits widespread ribosome stalling and induction of quality control biorxiv.org/cgi/content/sh… #biorxiv_molbio
We think this GitHub-based workflow will make bench research more reproducible, collaborative, and efficient—saving time and money. We found this to be the case after 9+ years of using it in our group!
You can find examples of these steps and more in our demo GitHub repository: github.com/rasilab/github…. Feel free to copy it to your GitHub account, ping us for help, or provide feedback by opening a new issue in the repo.
In our new manuscript with @klathrin_chen and Maria Toro-Moreno arxiv.org/abs/2408.09344, we show how wet-lab research groups can use GitHub to replace electronic lab notebooks, Slack-like collaboration tools, and software package managers. Here are the first three steps:
Thanks to our wonderful co-authors and collaborators including @klathrin_chen and @HsiehLab ! 11/
You can find more details in our bioRxiv manuscript: biorxiv.org/content/10.110…. 10/
RNAs are spliced, translated, and degraded in cells. How do we identify the cellular factors that control these RNA metabolic events in human cells? To tackle this question, grad student Patrick Nugent has developed an RNA-linked CRISPR screening technology called ReLiC. 1/
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