Somatic Cell Genome Editing (SCGE) Outreach @somaticediting
The Somatic Cell Genome Editing Consortium is funded by the @NIH_CommonFund. Retweets ≠ endorsements. Visit the SCGE Platform https://t.co/HSVaRDh4B4 scge.mcw.edu Joined September 2019-
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Somatic Cell Genome Editing (SCGE) Outreach retweeted
📢 Registration and abstract submissions are officially open for Breakthroughs in Cell & Gene Therapy! Explore our 2026 program tracks, view abstract categories, and secure your spot today: asgct.org/breakthroughs
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We're excited to share the third edition of the SCGE Spotlight! Read the newsletter at linkedin.com/pulse/scge-spo…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
Great honor to receive this Outstanding Publication in Basic Research Award from our college UF COP. Our research lab published more than 10 journal papers in this fiscal year, showing our passion and dedication to R & D for finding the best cure ✊
A team of researchers employed tumor-tropic human mesenchymal stem cells as delivery vehicles for magnetotheranostic gold-iron oxide nanoflowers (GIONF), enabling widespread i.t. distribution and sustained retention in contrast to injection of naked GIONF. pmc.ncbi.nlm.nih.gov/articles/PMC12…
Industry News: Beam Therapeutics Announces Clearance of Investigational New Drug Application for BEAM-304 for the Treatment of Phenylketonuria (PKU) by the United States (U.S.) Food and Drug Administration investors.beamtx.com/news-releases/…
Dr. Clark is a Research Scientist at the Medical College of Wisconsin, and is part of the SCGE Translational Coordination and Dissemination Center (TCDC). Find the free resources mentioned in the video at scge.mcw.edu/platform/home
In this "Meet the Researcher Interview", hear from Karen Clark, PhD, as she highlights the free resources available on the SCGE platform. youtube.com/watch?v=O2gjl0…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
Today we provided a regulatory update on a path forward for AMT-130 for #huntingtonsdisease. Read the full update: uniqure.gcs-web.com/news-releases/…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
In 3 new studies, @davidrliu's lab has optimized key prime editing components (guide pegRNA motifs, reverse transcriptase stability and delivery via lipid nanoparticles), addressing bottlenecks that previously impeded its use in animals and human patients. broad.io/PrimeEditing3
Somatic Cell Genome Editing (SCGE) Outreach retweeted
FDA is accepting applications until June 30, 2026, for the Rare Disease Endpoint Advancement (RDEA) Pilot Program, which supports novel efficacy endpoint development for drugs that treat rare diseases. Learn more & submit your application today ➡️ fda.gov/drugs/developm…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
Today in @NatureNano, we report an all-RNA lipid nanoparticle (LNP) system for efficient in vivo prime editing (PE). We identify bottlenecks in transient prime editor delivery, develop a workflow for LNP optimization, and use it to rescue a mouse model of phenylketonuria. drive.google.com/file/d/1-rPAaa… 1/12
CRISPR-based gene editing therapies are entering the clinic, offering transformative potential but also presenting potential risks. Preclinical-to-clinical toolkits are needed to assess safety and efficacy of these new therapies and accelerate progress. nature.com/articles/s4157…
Dr. Pan is a Research Assistant Professor at the University of Florida College of Pharmacy, and is part of the SCGE project titled "Evaluation of High-throughput Extracellular Vesicle Loading Platform for Therapeutic Genome Editing INDs".
In this SCGE "Meet the Researcher" interview, hear from Dr. Xiaoshu Pan as she highlights the benefits of extracellular vesicles (EVs) as a delivery method for gene therapies, and discusses the next milestones in her SCGE project. Watch the interview: youtube.com/watch?v=0HTRPl…
Using a multifaceted approach, SCGE researchers identified reduced levels of SPTAN1, a cytoskeletal spectrin protein, as a key regulator of RAC1 activation and cystic pathology in autosomal recessive polycystic kidney disease (ARPKD). advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
Dr. He is an Associate Professor at the University of Florida College of Pharmacy, and is the PI on the SCGE project titled "Evaluation of High-throughput Extracellular Vesicle Loading Platform for Therapeutic Genome Editing INDs". scge.mcw.edu/phase-2-techno…
In this SCGE researcher interview, Dr. Mei He highlights how her teams' high-throughput extracellular vesicle loading platform improves the delivery of genome editors and discusses the breadth of expertise needed to build her research project. @UF_HE_LAB youtube.com/watch?v=cmoriI…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
Today, the FDA published a draft guidance that when finalized will outline how sponsors can use publicly available information and established platform knowledge to streamline the development of cell and gene therapy products. fda.gov/news-events/pr…
Somatic Cell Genome Editing (SCGE) Outreach retweeted
On Thursday June 4, 2026, from 11 am – 12 PM ET, the Office of Therapeutic Products will host a virtual town hall with experts from OTP’s Office of Review Management & Regulatory Review answering questions regarding Biologic License Application readiness. fda.gov/vaccines-blood…
Here, SCGE researchers present a biomimetic microcapillary network, high-speed imaging, and computational algorithms to analyze red blood cell capillary velocity profiles of the entire sample population at single-cell resolution. #PublicationFriday pmc.ncbi.nlm.nih.gov/articles/PMC12…
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