Karen Maxwell @theMaxwellLab
Phage biologist focused on virus-host interactions and bacterial pathogenesis. themaxwelllab.com Toronto, Ontario Joined January 2016-
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Karen Maxwell retweeted
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases. I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known. People can contact me directly at my first name (as written in my profile) at octant.bio.
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Karen Maxwell retweeted
New paper with @theMaxwellLab : Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication doi.org/10.1128/mbio.0…
Amazing work by @LandonGetz and team!
@JoeBMcPhee I agree. What kind of animal does that?
There are people that submit their grants more than 8 minutes ahead of the deadline???
If you submit your grants last minute, you're in good company. Half of the applications were submitted in the last two days, in the 2005 NIH Pioneer grant cycle. The red bars indicate the awardees; one of them submitted just 8 minutes before the deadline.
Karen Maxwell retweeted
🚨New preprint from our lab! We map the RNA interactions in E. coli infected by lambda, revealing an RNA-driven regulatory layer in phage-host dynamics. We find a phage-encoded sRNA hijacking host replication machinery, impacting the phage cycle.#microbiology #phages @MeetingRna
Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Karen Maxwell retweeted
We’re here at @WCHospital for the #GairdnerScienceWeek Women of Gairdner Event! High school students, researchers and local faculty are here with 2024 Canada Gairdner Award laureates Drs. Meghan Azad, Gagandeep Kang, and 2022 #GairdnerAwards winner Dr. Deborah Cook Watch the webinar now! us02web.zoom.us/webinar/regist…
Karen Maxwell retweeted
Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces. Postdoc: shorturl.at/f8NTN PhD position: shorturl.at/qCFmN Email me for more information.
Karen Maxwell retweeted
This was a wonderful meeting @SPP2330 again! Great kick-off of our second funding period! Amazing science going on in the phage field and great to see students/postdocs from the first funding period starting their independent labs. @dfg_public, @fz_juelich, @HHU_de
Karen Maxwell retweeted
Julia Frunzke @FrunzkeLab opening the annual @SPP2330 meeting! Looking forward to 3 exciting days of science! @dfg_public
Karen Maxwell retweeted
We are ready to go for the Annual SPP2330 Meeting on “New Concepts in Prokaryotic Virus-host Interactions”! With a fantastic line up of speakers: Alexander Harms @AHarms485, Karen Maxwell @theMaxwellLab, Samuel Kilcher @SamuelKilcher, and Mathias Middelboe @mmiddelboe1
@PRSecor @MSU_MicroImmuno @montanastate Wow! Congratulations Pat!!!!
@Bruce_G_Allen MID panel success rate was only 13.3% (8 of 60). I suspect that the 15.3% rate may be bolstered by one year bridge grants.
Karen Maxwell retweeted
Rare opportunity to join my team, as the @PLOSBiology in-house editorial team is growing! It's a great team in a great journal, if I say so myself 😆 Please reach out if your have Qs & apply if interested!! UK or US; assoc or senior Please RT us241.dayforcehcm.com/CandidatePorta…
Karen Maxwell retweeted
A supervisor, postdoc and the new PhD candidate x.com/i/status/18089…
@liyuping927 @biozentrum @NCCR_AntiResist @UniBasel_en @ElginKorkmazhan Congratulations! Looking forward to seeing some cool work coming out of your new lab!!
Karen Maxwell retweeted
Congratulations to @UofT_dlsph postdoc fellow @michelle_olding on receiving the 2024 EPIC Career Transition Award to lead an independent project looking at the role of prescribed safer supply programs in improving access to HIV and HCV care! Read more: bit.ly/45x0Quk
@MarraffiniLab @AKShilton Congratulations again Amanda - you did a wonderful job! Thanks again for inviting me to be part of your big day!!!
Karen Maxwell retweeted
Anti-phage defence through inhibition of virion assembly @theMaxwellLab @pramalpatel #phages #antiphage #prophages #phagedefence #bacteria #microbiology #virology nature.com/articles/s4146…
This is definitely one of the longest running projects in the lab b/c we were stuck in a trap of thinking about Sie proteins blocking competing phages. But wasn't a satisfying answer to fit the biology we observed - kudos to @vee_coli for persevering and figuring it out!
New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect. biorxiv.org/content/10.110…
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