Nicole Pek (she/her) @two_cells
PhD Candidate @cincychildrens @UcincyMedicine •@AHAScience Fellow •Albert J. Ryan Fellow •@NUSingapore Young Fellow •Founder @npbiomeds (Views = my own) twocells.medium.com Cincinnati, OH Joined August 2020-
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Excited to share that my PhD thesis work is now available as a preprint! shorturl.at/vgfzv This work represents a long but rewarding journey. Grateful to my PIs @MingxiaGu and @ZornLab, and all our collaborators for their help and guidance. #organoids #NAMs #iPSCs
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@jgomezarroyo @MingxiaGu @ZornLab Thank you Jose!
Nicole Pek (she/her) retweeted
Online Now! Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia dlvr.it/TQ0H2z #stemcells
Join me next week in @vascularbiology's InFocus Session, where I'll be giving a short presentation on my thesis project 'Distinct Functional Consequences of FOXF1 Mutations in Capillary Development'. Registration is free: shorturl.at/T12dx
Nicole Pek (she/her) retweeted
Drs. @SimonMiao6, Nicole Pek (@two_cells), and Drs. Minzhe Guo and @MingxiaGu's labs co-differentiated mesoderm and endoderm in the same spheroid to vascularize lung and intestinal #organoids! @CellCellPress article: bit.ly/3H1ar4V Discussion: bit.ly/44YrzjU
Thrilled to share that I’ve been selected as one of 19 recipients for the 2025 @GenScript Life Science Research Grant (First Award Cycle). This grant will support our efforts to validate the utility of LNP-mRNA in treating vascular diseases.
Nicole Pek (she/her) retweeted
@MingxiaGu @CellCellPress @CuSTOM_CCHMC @UCLAstemcell Read more at our Research Horizons science blog: scienceblog.cincinnatichildrens.org/first-lung-org…
Nicole Pek (she/her) retweeted
Excited to share our recent work on organoid vascularization, now out in @CellCellPress! Grateful to all our amazing collaborators who made this possible! @CuSTOM_CCHMC @UCLAstemcell
Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! "Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids" cell.com/cell/fulltext/…
By employing developmental principles, we were able to overcome long-standing challenges in the field - 1) inadequate vascularization of gut organoids, 2) ECs and mesenchyme void of organ-features. A major milestone in vascular biology organoid research!
Our Cell paper is now online!! 💡We share a mesoderm-endoderm co-differentiation strategy to achieve organ-specific #endothelial & #mesenchymal cells in vascularized #lung and intestinal #organoids. 🔗sciencedirect.com/science/articl…
Nicole Pek (she/her) retweeted
Excited to share our latest study showing that restoring the balance between NTRK2 isoforms offers a promising therapeutic approach to promote pulmonary vascular regeneration! biorxiv.org/content/10.110…
Nicole Pek (she/her) retweeted
Your lungs make blood too. UCSF scientists just discovered lung stem cells that produce blood, just like bone marrow. This could change how we treat blood and immune disorders. tiny.ucsf.edu/Pwa7qn
Nicole Pek (she/her) retweeted
Our new metabolic method to generate highly-pure hepatocyte-like cells is out in @biorxivpreprint where we study the effect of biosafety-level-4 viruses using these purified hepatocyte-like cells. biorxiv.org/content/10.110….
Thankful for the partnership with @miltenyibiotec , whose cutting-edge products are vital to my research. Their solutions are key to my work on stem cell-derived vessel organoids for modeling disease and development, making a huge impact on my progress. shorturl.at/0zs2v
Nicole Pek (she/her) retweeted
@WindDustStars Women are naturally less interested in these fields and that’s why they are less active in STEM? That’s total bs. For one, maybe look up the misogyny women in STEM experience - from daily interactions all the way up to the Nobel! education.nationalgeographic.org/resource/women…
Curious about how our brain distinguishes 'doorbells' from 'eggs' or know when words are gibberish? Don't miss my latest blog article where I dissect a recent study that uncovered how our brain processes semantic information at a single-cell level - shorturl.at/Re6rh
Nicole Pek (she/her) retweeted
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Amazing to see Dr. @TakebeLab and team's study on 'butt-breating' receive such an incredible accolade and recognition. If you'll like to learn more about anal breathing, I wrote a an article on my blog a couple months back on this - shorturl.at/LS0h9 Please check it out!
Can people really breathe through their butts? Mammals can. So people probably can, too. Congrats to @TakebeLab @CuSTOMOrganoids @CincyChildrens One of 10 winners of a 2024 #IgNobel Prize! Read more: scienceblog.cincinnatichildrens.org/ig-nobel-prize… Watch the ceremony: improbable.com/ig/archive/202…
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