1/n 🚨 New Paper Alert 🚨. I am excited to announce a new piece of work in an emerging research area I am passionate about. We introduce FEET: A Framework for Evaluating Embedding Techniques, which provide a principled reporting method for evaluating foundation models...
Using complex models to detect genetic interactions (epistasis) can boost power, but how do we quantify their importance and interpret those 'epistasis signals'?
In our latest Genome Research paper, we revisit the simplest form—quadratic interactions—and introduce a scalable algorithm for in-depth epistasis quantification. Our findings highlight the unignorable and heterogeneous impact of epistasis in human genetics.
Many thanks to Prateek Anand, Aakarsh Anand, Dr. Joel Mefford, and my PI, Prof. @sr_sankararaman!
Full text: genome.cshlp.org/content/early/…
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